Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrus blythi) in Pakistan as confirmed by detection of antigen and antibody - PubMed (original) (raw)

Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrus blythi) in Pakistan as confirmed by detection of antigen and antibody

Muhammad Abubakar et al. Trop Anim Health Prod. 2011 Apr.

Abstract

An outbreak resulting in mortality in Sindh Ibex (Capra aegagrus blythi) was investigated. There was a history of about 36 deaths (both young and adult) during the period of 1 month. Disease appeared in a generalized form, affecting the respiratory and digestive systems. Major lesions were respiratory distress, pustules on and in the mouth, ocular-nasal discharges, and severe diarrhea. The most significant lesion was the oculonasal discharges and diarrhea. Deaths were mainly due to blindness, anorexia, diarrhea, and respiratory arrest. Both adult (mortality = 21) and young (mortality = 15) animals were affected with the disease. Peste des petits ruminants virus (PPRV) antigen was detected in the spleen, lung, lymph node, and swab samples by immunocapture enzyme-linked immunosorbent assay. Spleen and lung samples were also tested and found positive for the presence of F-gene of PPRV by polymerase chain reaction. Thirteen of 20 serum samples from nearby sheep and goats were found positive for antibodies to PPRV. The disease threatened the huge population of ibex in the wild life park, which was spread over a large area, but vaccination of the domestic population of sheep and goats in the surrounding villages appeared to control the disease.

PubMed Disclaimer

Similar articles

• Evidence of peste des petits ruminants in serology of sheep and goats from Sindh, Pakistan.
  Abubakar M, Arshed MJ, Hussain M, Ali Q. Abubakar M, et al. Transbound Emerg Dis. 2011 Apr;58(2):152-6. doi: 10.1111/j.1865-1682.2010.01193.x. Epub 2010 Dec 20. Transbound Emerg Dis. 2011. PMID: 21167015
• Prevalence and distribution of peste des petits ruminants virus infection in small ruminants in India.
  Singh RP, Saravanan P, Sreenivasa BP, Singh RK, Bandyopadhyay SK. Singh RP, et al. Rev Sci Tech. 2004 Dec;23(3):807-19. doi: 10.20506/rst.23.3.1522. Rev Sci Tech. 2004. PMID: 15861876
• Molecular characterization of peste des petits ruminants viruses from outbreaks caused by unrestricted movements of small ruminants in pakistan.
  Munir M, Saeed A, Abubakar M, Kanwal S, Berg M. Munir M, et al. Transbound Emerg Dis. 2015 Feb;62(1):108-14. doi: 10.1111/tbed.12089. Epub 2013 Apr 17. Transbound Emerg Dis. 2015. PMID: 23590481
• Peste des petits ruminants virus (PPRV) infection; its association with species, seasonal variations and geography.
  Abubakar M, Jamal SM, Arshed MJ, Hussain M, Ali Q. Abubakar M, et al. Trop Anim Health Prod. 2009 Oct;41(7):1197-202. doi: 10.1007/s11250-008-9300-9. Epub 2009 Jan 7. Trop Anim Health Prod. 2009. PMID: 19130284
• Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control.
  Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Banyard AC, et al. J Gen Virol. 2010 Dec;91(Pt 12):2885-97. doi: 10.1099/vir.0.025841-0. Epub 2010 Sep 15. J Gen Virol. 2010. PMID: 20844089 Review.

Cited by

• Early events following experimental infection with Peste-Des-Petits ruminants virus suggest immune cell targeting.
  Pope RA, Parida S, Bailey D, Brownlie J, Barrett T, Banyard AC. Pope RA, et al. PLoS One. 2013;8(2):e55830. doi: 10.1371/journal.pone.0055830. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418464 Free PMC article.
• Evaluation of Risk Factors for Peste des Petits Ruminants Virus in Sheep and Goats at the Wildlife-Livestock Interface in Punjab Province, Pakistan.
  Aziz-Ul-Rahman, Abubakar M, Rasool MH, Manzoor S, Saqalein M, Rizwan M, Munir M, Ali Q, Wensman JJ. Aziz-Ul-Rahman, et al. Biomed Res Int. 2016;2016:7826245. doi: 10.1155/2016/7826245. Epub 2016 May 15. Biomed Res Int. 2016. PMID: 27294134 Free PMC article.
• Expanding Diversity of Susceptible Hosts in Peste Des Petits Ruminants Virus Infection and Its Potential Mechanism Beyond.
  Dou Y, Liang Z, Prajapati M, Zhang R, Li Y, Zhang Z. Dou Y, et al. Front Vet Sci. 2020 Feb 28;7:66. doi: 10.3389/fvets.2020.00066. eCollection 2020. Front Vet Sci. 2020. PMID: 32181263 Free PMC article. Review.
• A predictive analysis on the risk of peste des petits ruminants in livestock in the Trans-Himalayan region and validation of its transboundary transmission paths.
  Zeng Z, Gao S, Wang HN, Huang LY, Wang XL. Zeng Z, et al. PLoS One. 2021 Sep 10;16(9):e0257094. doi: 10.1371/journal.pone.0257094. eCollection 2021. PLoS One. 2021. PMID: 34506571 Free PMC article.
• A comparative phylogenomic analysis of peste des petits ruminants virus isolated from wild and unusual hosts.
  Rahman AU, Munir M, Shabbir MZ. Rahman AU, et al. Mol Biol Rep. 2019 Oct;46(5):5587-5593. doi: 10.1007/s11033-019-04973-7. Epub 2019 Jul 17. Mol Biol Rep. 2019. PMID: 31317455

References

1. 1. J Vet Med B Infect Dis Vet Public Health. 2004 Mar;51(2):68-71 - PubMed
2. 1. Vet Rec. 1997 Nov 29;141(22):573-4 - PubMed
3. 1. Vet Rec. 1994 Mar 19;134(12):300-4 - PubMed
4. 1. Virus Res. 1995 Dec;39(2-3):151-63 - PubMed
5. 1. Epidemiol Infect. 1994 Feb;112(1):225-31 - PubMed

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Ovid Technologies, Inc.
  • Springer