[Purulent pericarditis and colonic infiltrating to Salmonella enteritidis complicated by acute intussusception in a case of IL-12Rβ1 deficiency] - PubMed (original) (raw)
Case Reports
. 2014 Dec;21(12):1348-52.
doi: 10.1016/j.arcped.2014.09.009. Epub 2014 Nov 4.
[Article in French]
Affiliations
- PMID: 25445126
- DOI: 10.1016/j.arcped.2014.09.009
Case Reports
[Purulent pericarditis and colonic infiltrating to Salmonella enteritidis complicated by acute intussusception in a case of IL-12Rβ1 deficiency]
[Article in French]
F Ailal et al. Arch Pediatr. 2014 Dec.
Abstract
IL-12 receptor β1 deficiency (IL-12Rβ1) predisposes patients to mycobacteria and Salmonella infections. We report a case of IL-12Rβ1 deficiency with a fatal multi-resistant Salmonella enteritidis infection. This boy was born after from a consanguineous marriage, and diagnosed as having a IL-12Rβ1 deficiency since the age of 3 months. He presented with recurrent Salmonella enteritidis essentially digestive localization, complicated by purulent pericarditis at the same germ at the age of two and a half years. At the age of 3, a colonic infiltration due to a Salmonella enteritidis resistant to antibiotics, was complicated by acute intussusception, and the child died. The IL-12Rβ1 deficiency is considered as having a good prognosis, in contrast to what happened in our patient. We review therapeutic issues in these patients.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.
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