Adipocytic tumors in Children: A contemporary review - PubMed (original) (raw)
Review
Adipocytic tumors in Children: A contemporary review
Juan Putra et al. Semin Diagn Pathol. 2019 Mar.
Abstract
Adipocytic neoplasms in the pediatric population demonstrate a different histologic spectrum and frequency than in adults. The vast majority of these tumors are benign, with lipoma being the most common entity. The identification of signature cytogenetic and molecular alterations for certain lesions, such as PLAG1 gene rearrangement in lipoblastoma and FUS-DDIT3 fusion in myxoid liposarcoma, has been helpful in approaching these neoplasms and aiding in confirming the diagnosis. Furthermore, it is important for pathologists to recognize that adipocytic neoplasms may be associated with different syndromes with potential impact in managing such patients. This review provides a summary of the clinical pictures, histologic characteristics, molecular alterations, differential diagnoses, and syndromic associations of the commonly encountered fatty tumors in children.
Keywords: Adipocytic; Lipofibromatosis; Liposarcoma; Myxoid liposarcoma; Pediatric.
Published by Elsevier Inc.
Similar articles
- A contemporary review of myxoid adipocytic tumors.
Creytens D. Creytens D. Semin Diagn Pathol. 2019 Mar;36(2):129-141. doi: 10.1053/j.semdp.2019.02.008. Epub 2019 Feb 28. Semin Diagn Pathol. 2019. PMID: 30853315 Review. - [Adipocytic tumors].
Stock N. Stock N. Ann Pathol. 2015 Jan;35(1):41-53. doi: 10.1016/j.annpat.2014.12.001. Epub 2014 Dec 20. Ann Pathol. 2015. PMID: 25533918 Review. French. - [Tumors with predominantly adipocytic morphology].
Wardelmann E, Hartmann W. Wardelmann E, et al. Pathologe. 2019 Jul;40(4):339-352. doi: 10.1007/s00292-019-0624-1. Pathologe. 2019. PMID: 31240452 German. - Lipoblastoma and liposarcoma in children: an analysis of 9 cases and a review of the literature.
Miller GG, Yanchar NL, Magee JF, Blair GK. Miller GG, et al. Can J Surg. 1998 Dec;41(6):455-8. Can J Surg. 1998. PMID: 9854536 Free PMC article. Review. - What's new in adipocytic neoplasia?
Thway K. Thway K. Histopathology. 2022 Jan;80(1):76-97. doi: 10.1111/his.14548. Histopathology. 2022. PMID: 34958506 Review.
Cited by
- An Unusual Paediatric Neck Mass: Cervical Lipoblastoma with Spinal Involvement.
Quah GXP, Aziz A, Mohamad H, Sheikh Ab Hamid S, Ang SY. Quah GXP, et al. Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4673-4676. doi: 10.1007/s12070-024-04766-w. Epub 2024 Jun 6. Indian J Otolaryngol Head Neck Surg. 2024. PMID: 39376358 - Insights on Lipomatosis after Platinum-Based Chemotherapy Use in Pediatric Oncology: A Case Report.
Boeriu E, Boc AG, Borda A, Negrean RA, Feciche B, Boeriu AI, Horhat FG, Mot IC, Horhat ID, Ravulapalli M, Sabuni O, Adi A, Anjary A, Arghirescu ST. Boeriu E, et al. Medicina (Kaunas). 2022 Nov 23;58(12):1715. doi: 10.3390/medicina58121715. Medicina (Kaunas). 2022. PMID: 36556917 Free PMC article. - Lipoblastoma in one adult and 35 pediatric patients: Retrospective analysis of 36 cases.
Zhang W, Zhang S, Yang Z, Zhang Y, Wang Z. Zhang W, et al. Exp Ther Med. 2022 Nov 16;25(1):11. doi: 10.3892/etm.2022.11710. eCollection 2023 Jan. Exp Ther Med. 2022. PMID: 36561624 Free PMC article. - Lipoblastomas and liposarcomas in paediatric patients: A case series.
McRae JJLH, Hashmi A, Radulescu A, Carter CS, Khan FA. McRae JJLH, et al. J Int Med Res. 2021 Mar;49(3):300060520981362. doi: 10.1177/0300060520981362. J Int Med Res. 2021. PMID: 33730887 Free PMC article. - Update of pediatric soft tissue tumors with review of conventional MRI appearance-part 1: tumor-like lesions, adipocytic tumors, fibroblastic and myofibroblastic tumors, and perivascular tumors.
Porrino J, Al-Dasuqi K, Irshaid L, Wang A, Kani K, Haims A, Maloney E. Porrino J, et al. Skeletal Radiol. 2022 Mar;51(3):477-504. doi: 10.1007/s00256-021-03836-2. Epub 2021 Jun 30. Skeletal Radiol. 2022. PMID: 34191084 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials