Liquid chromatographic and mass spectral analysis of N-substituted analogues of 3,4-methylenedioxyamphetamine - PubMed (original) (raw)
Liquid chromatographic and mass spectral analysis of N-substituted analogues of 3,4-methylenedioxyamphetamine
F T Noggle Jr et al. J Chromatogr Sci. 1988 Aug.
Abstract
The C1 to C3 N-alkyl, N,N-dimethyl, and N-hydroxy analogues of 3,4-methylenedioxyamphetamine (MDA) are identified by high performance liquid chromatographic (HPLC) and spectrometric techniques. The compounds are separated using reversed-phase procedures on C18 stationary phase with an acidic (pH 3) aqueous methanol mobile phase. The mass spectra of the compounds are distinctive and reference spectra are provided. The N-hydroxy derivative is unstable at high temperatures and decomposes to MDA and the oxime of 3,4-methylenedioxyphenyl-2-propanone.
Similar articles
- Liquid chromatographic and mass spectral analysis of 1-(3,4-methylenedioxyphenyl)-3-butanamines, homologues of 3,4-methylenedioxyamphetamines.
Noggle FT Jr, Clark CR, DeRuiter J. Noggle FT Jr, et al. J Chromatogr Sci. 1989 May;27(5):240-3. doi: 10.1093/chromsci/27.5.240. J Chromatogr Sci. 1989. PMID: 2745665 - Spectrophotometric and liquid chromatographic identification of 3,4-methylenedioxyphenylisopropylamine and its N-methyl and N-ethyl homologs.
Noggle FT Jr, DeRuiter J, Long MJ. Noggle FT Jr, et al. J Assoc Off Anal Chem. 1986 Jul-Aug;69(4):681-6. J Assoc Off Anal Chem. 1986. PMID: 2875058 - Liquid chromatographic and mass spectral analysis of 1-(3,4-methylenedioxyphenyl)-1-propanamines: regioisomers of the 3,4-methylenedioxyamphetamines.
DeRuiter J, Clark CR, Noggle FT Jr. DeRuiter J, et al. J Chromatogr Sci. 1990 Mar;28(3):129-32. doi: 10.1093/chromsci/28.3.129. J Chromatogr Sci. 1990. PMID: 2273067 - Methods for the analysis of 1-(3,4-methylenedioxyphenyl)-2-butanamine and N-methyl-1-(3,4-methylenedioxyphenyl)-2-propanamine (MDMA).
Noggle FT Jr, Clark CR, Andurkar S, DeRuiter J. Noggle FT Jr, et al. J Chromatogr Sci. 1991 Mar;29(3):103-6. doi: 10.1093/chromsci/29.3.103. J Chromatogr Sci. 1991. PMID: 1676403 - Techniques for the detection and identification of amphetamines and amphetamine-like substances.
Rasmussen KE, Knutsen P. Rasmussen KE, et al. Bull Narc. 1985 Jan-Mar;37(1):95-112. Bull Narc. 1985. PMID: 3904880 Review.
Cited by
- A synthetic cannabinoid FDU-NNEI, two 2_H_-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative _N_-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products.
Uchiyama N, Shimokawa Y, Kikura-Hanajiri R, Demizu Y, Goda Y, Hakamatsuka T. Uchiyama N, et al. Forensic Toxicol. 2015;33(2):244-259. doi: 10.1007/s11419-015-0268-7. Epub 2015 Feb 11. Forensic Toxicol. 2015. PMID: 26257833 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous