No TP53 mutations in neuroblastomas detected by PCR-SSCP analysis - PubMed (original) (raw)

No TP53 mutations in neuroblastomas detected by PCR-SSCP analysis

J S Castresana et al. Genes Chromosomes Cancer. 1994 Jun.

Abstract

We have analysed 29 neuroblastomas for TP53 mutations in exons 5 to 8 by means of the polymerase chain reaction in combination with the single-strand conformation polymorphism technique. We could not detect any mutation. These results indicate that, in contrast to the majority of tumors so far studied, TP53 mutations do not seem to be important for the development of neuroblastomas.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Wiley

• Medical

  • MedlinePlus Health Information

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal