Directing alternative splicing: cast and scenarios - PubMed (original) (raw)

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Directing alternative splicing: cast and scenarios

B Chabot. Trends Genet. 1996 Nov.

Abstract

Recent progress in the study of alternative RNA splicing indicates that the interaction of RNA-binding proteins with specific target elements modulates splice site recognition and spliceosome assembly. The identity of splicing signals, the presence of modulating elements and differences in the distribution of RNA-binding proteins are key determinants involved in the tissue-specific regulation of splice site selection.

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