Peptides by activation of amino acids with CO on (Ni,Fe)S surfaces: implications for the origin of life - PubMed (original) (raw)
Peptides by activation of amino acids with CO on (Ni,Fe)S surfaces: implications for the origin of life
C Huber et al. Science. 1998.
Abstract
In experiments modeling volcanic or hydrothermal settings amino acids were converted into their peptides by use of coprecipitated (Ni,Fe)S and CO in conjunction with H2S (or CH3SH) as a catalyst and condensation agent at 100 degreesC and pH 7 to 10 under anaerobic, aqueous conditions. These results demonstrate that amino acids can be activated under geochemically relevant conditions. They support a thermophilic origin of life and an early appearance of peptides in the evolution of a primordial metabolism.
Comment in
- A sulfurous start for protein synthesis?
Vogel G. Vogel G. Science. 1998 Jul 31;281(5377):627, 629. doi: 10.1126/science.281.5377.627a. Science. 1998. PMID: 9714669 No abstract available.
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