Leila Ghalichi | Tehran University of Medical Sciences (original) (raw)

Papers by Leila Ghalichi

Research paper thumbnail of Booster dose vaccination for preventing hepatitis B

… Database Syst Rev, Jan 1, 2010

Research paper thumbnail of Incidence, Severity and Risk Factors for Retinopathy of Prematurity in Premature Infants with Late Retinal Examination

Bina Journal of …, Jan 1, 2010

Research paper thumbnail of The Effect of MRI 3 Tesla in Diagnosis and Treatment of Neurological and Heart Diseases: Systematic Review

Journal of Isfahan …, Jan 1, 2011

Research paper thumbnail of Retinopathy of prematurity in infants with late retinal examination

Journal of Ophthalmic & …, Jan 1, 2009

Purpose: To report the incidence, severity and risk factors of retinopathy of prematurity (ROP) i... more Purpose: To report the incidence, severity and risk factors of retinopathy of prematurity (ROP) in premature infants with late ROP examination in Farabi Eye Hospital. Methods: In a retrospective study from January 2001 to July 2007, hospital records of premature infants who were examined later than 9 weeks after birth were reviewed to determine the incidence, severity and possible risk factors of ROP including gender, singleton or multiple gestations, gestational age (GA), birth weight (BW), oxygen therapy, blood transfusion, phototherapy, respiratory distress syndrome (RDS), mechanical ventilation, intraventricular hemorrhage and sepsis as well as age at initial examination. Results: Out of a total of 797 infants referred for ROP screening during the study period, 216 (27.1%) had late examinations at a mean age of 141.7±150.4 (range 64-1,460) days. Of these, 87 (40.3%) had different stages of ROP, 65 (30.1%) had stage 4 or 5 disease including 34 (16.2%) infants with stage 5 ROP in both eyes which was untreatable. Lower GA (P<0.001), RDS (P=0.041) and blood transfusion (P=0.009) were associated with the development of ROP. Conclusion: The overall prevalence of ROP and the incidence of severe ROP in particular, were unacceptably high in premature infants with late screening. These findings necessitate interventions to optimize timely referral for screening of premature infants.

Research paper thumbnail of Screening for retinopathy of prematurity: the role of educating the parents

Iranian Journal of …, Jan 1, 2010

Purpose: Childhood blindness due to retinopathy of prematurity (ROP) is an important concern, but... more Purpose: Childhood blindness due to retinopathy of prematurity (ROP) is an important concern, but this blindness or severe visual impairment may be prevented if at risk infants are screened before occurrence of advanced stages. In this study, we tried to find the role of parental education about ROP in parents' compliance for on-time attendance for ROP screening. Methods: Demographic factors and clinical information of all the consecutive infants screened for ROP in Farabi Eye Hospital during 2003-2007 were recorded and analyzed using independent sample T-test, chi-square and multiple logistic regressions.

Research paper thumbnail of Characteristics of Advanced Stages of Retinopathy of Prematurity

Iranian Journal of …, Jan 1, 2010

Purpose: To evaluate the incidence and risk factors of severe visual impairment and retinopathy o... more Purpose: To evaluate the incidence and risk factors of severe visual impairment and retinopathy of prematurity (ROP)-related blindness in a tertiary eye hospital in Iran Methods: In a cross-sectional study, clinical data of premature infants screened for ROP in Farabi Eye Hospital during 2003-2007 were reviewed. Characteristics of advanced stages of ROP (stage 4 or 5) were determined and compared to other stages of ROP.

Research paper thumbnail of Seroprotection of hepatitis B vaccine and need for booster dose: a meta-analysis

Hepatitis Monthly, Jan 1, 2009

Hepat Mon 2009; 9 (4): 293-304 Background and Aims: The duration of protection provided by hepati... more Hepat Mon 2009; 9 (4): 293-304 Background and Aims: The duration of protection provided by hepatitis B (HB) vaccine is still unknown but can be estimated indirectly by measuring the anamnestic immune response to booster doses of the vaccine. Methods: We searched electronic databases and conference databases up to December 2008. We also screened reference lists of articles and contacted the authors and vaccine manufacturers for additional references. We included randomized and nonrandomized studies assessing the anamnestic immune response to the booster of HB vaccine in healthy participants 5 years or more after initial vaccination. Results: The meta-analysis included 34 studies with 53 intervention groups and 4,479 individuals. The protective antibodies induced by initial vaccination waned over time; however, nonprotected vaccinees who had lost their antibodies to hepatitis B surface antigen (anti-HBs) over time responded strongly to the booster dose. The seroprotection rate of HB vaccine after the primary vaccination was 98.00% [95% confidence interval (CI): 95.32%, 99.52%] after 5 years, 96.88% [95% CI: 94.61%, 98.50%] after 6-10 years, 88.80% [95% CI: 79.84%, 95.08%] after 11-15 years, and 85.12% [95% CI: 82.18%, 88.20%] after 16-20 years.

Research paper thumbnail of Incidence and risk factors of retinopathy of prematurity in a tertiary eye hospital in Tehran

British Journal of …, Jan 1, 2008

Incidence and risk factors of retinopathy of http://bjo.bmj.com/cgi/content/full/92/11/1446 Updat... more Incidence and risk factors of retinopathy of http://bjo.bmj.com/cgi/content/full/92/11/1446 Updated information and services can be found at:

Research paper thumbnail of Booster dose vaccination for preventing hepatitis B

… Database Syst Rev, Jan 1, 2010

Research paper thumbnail of Incidence, Severity and Risk Factors for Retinopathy of Prematurity in Premature Infants with Late Retinal Examination

Bina Journal of …, Jan 1, 2010

Research paper thumbnail of The Effect of MRI 3 Tesla in Diagnosis and Treatment of Neurological and Heart Diseases: Systematic Review

Journal of Isfahan …, Jan 1, 2011

Research paper thumbnail of Retinopathy of prematurity in infants with late retinal examination

Journal of Ophthalmic & …, Jan 1, 2009

Purpose: To report the incidence, severity and risk factors of retinopathy of prematurity (ROP) i... more Purpose: To report the incidence, severity and risk factors of retinopathy of prematurity (ROP) in premature infants with late ROP examination in Farabi Eye Hospital. Methods: In a retrospective study from January 2001 to July 2007, hospital records of premature infants who were examined later than 9 weeks after birth were reviewed to determine the incidence, severity and possible risk factors of ROP including gender, singleton or multiple gestations, gestational age (GA), birth weight (BW), oxygen therapy, blood transfusion, phototherapy, respiratory distress syndrome (RDS), mechanical ventilation, intraventricular hemorrhage and sepsis as well as age at initial examination. Results: Out of a total of 797 infants referred for ROP screening during the study period, 216 (27.1%) had late examinations at a mean age of 141.7±150.4 (range 64-1,460) days. Of these, 87 (40.3%) had different stages of ROP, 65 (30.1%) had stage 4 or 5 disease including 34 (16.2%) infants with stage 5 ROP in both eyes which was untreatable. Lower GA (P<0.001), RDS (P=0.041) and blood transfusion (P=0.009) were associated with the development of ROP. Conclusion: The overall prevalence of ROP and the incidence of severe ROP in particular, were unacceptably high in premature infants with late screening. These findings necessitate interventions to optimize timely referral for screening of premature infants.

Research paper thumbnail of Screening for retinopathy of prematurity: the role of educating the parents

Iranian Journal of …, Jan 1, 2010

Purpose: Childhood blindness due to retinopathy of prematurity (ROP) is an important concern, but... more Purpose: Childhood blindness due to retinopathy of prematurity (ROP) is an important concern, but this blindness or severe visual impairment may be prevented if at risk infants are screened before occurrence of advanced stages. In this study, we tried to find the role of parental education about ROP in parents' compliance for on-time attendance for ROP screening. Methods: Demographic factors and clinical information of all the consecutive infants screened for ROP in Farabi Eye Hospital during 2003-2007 were recorded and analyzed using independent sample T-test, chi-square and multiple logistic regressions.

Research paper thumbnail of Characteristics of Advanced Stages of Retinopathy of Prematurity

Iranian Journal of …, Jan 1, 2010

Purpose: To evaluate the incidence and risk factors of severe visual impairment and retinopathy o... more Purpose: To evaluate the incidence and risk factors of severe visual impairment and retinopathy of prematurity (ROP)-related blindness in a tertiary eye hospital in Iran Methods: In a cross-sectional study, clinical data of premature infants screened for ROP in Farabi Eye Hospital during 2003-2007 were reviewed. Characteristics of advanced stages of ROP (stage 4 or 5) were determined and compared to other stages of ROP.

Research paper thumbnail of Seroprotection of hepatitis B vaccine and need for booster dose: a meta-analysis

Hepatitis Monthly, Jan 1, 2009

Hepat Mon 2009; 9 (4): 293-304 Background and Aims: The duration of protection provided by hepati... more Hepat Mon 2009; 9 (4): 293-304 Background and Aims: The duration of protection provided by hepatitis B (HB) vaccine is still unknown but can be estimated indirectly by measuring the anamnestic immune response to booster doses of the vaccine. Methods: We searched electronic databases and conference databases up to December 2008. We also screened reference lists of articles and contacted the authors and vaccine manufacturers for additional references. We included randomized and nonrandomized studies assessing the anamnestic immune response to the booster of HB vaccine in healthy participants 5 years or more after initial vaccination. Results: The meta-analysis included 34 studies with 53 intervention groups and 4,479 individuals. The protective antibodies induced by initial vaccination waned over time; however, nonprotected vaccinees who had lost their antibodies to hepatitis B surface antigen (anti-HBs) over time responded strongly to the booster dose. The seroprotection rate of HB vaccine after the primary vaccination was 98.00% [95% confidence interval (CI): 95.32%, 99.52%] after 5 years, 96.88% [95% CI: 94.61%, 98.50%] after 6-10 years, 88.80% [95% CI: 79.84%, 95.08%] after 11-15 years, and 85.12% [95% CI: 82.18%, 88.20%] after 16-20 years.

Research paper thumbnail of Incidence and risk factors of retinopathy of prematurity in a tertiary eye hospital in Tehran

British Journal of …, Jan 1, 2008

Incidence and risk factors of retinopathy of http://bjo.bmj.com/cgi/content/full/92/11/1446 Updat... more Incidence and risk factors of retinopathy of http://bjo.bmj.com/cgi/content/full/92/11/1446 Updated information and services can be found at: