Abdulgafar Jimoh | Usmanu Danfodiyo University (original) (raw)

Papers by Abdulgafar Jimoh

Nigerian Journal of Clinical Practice

Background: The rate of complementary and alternative medicine (CAM) use among cancer patients is... more Background: The rate of complementary and alternative medicine (CAM) use among cancer patients is on the increase worldwide. This is due to the innate urge among humans to try new and alternative ways of medicine, especially where conventional medicine failed to provide satisfactory solution such as in sickle cell disease and cancer. Objective: To assess the prevalence and correlates of CAM use among cancer patients in Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, Nigeria. Materials and Methods: A cross-sectional study was conducted among 240 cancer patients selected by systematic sampling technique from July to September 2016. Data were collected using a semi-structured standardized questionnaire. Results: The mean age of the study participants was 45 ± 13.7 years. Majority, 159 (66.3%) of the 240 respondents, were CAM users, with the most common methods being prayer (30.8%) and herbal therapy (28.3%). Majority of CAM users (64.2%) did not derive any benefit from CAM use, but rather reported adverse effects such as nausea and vomiting (52.5%) and diarrhea (44.2%). Physicians were unaware of CAM use in most cases (87.4%), and this was majorly attributed to the physicians not asking them about CAM use. Male sex and absence of comorbidities were the predictors of CAM use identified. Conclusion: The prevalence of CAM use is high among cancer patients in UDUTH, Sokoto, Nigeria, but the physicians were largely unaware of CAM use due to communication gap. These findings underscore the need for physicians to consistently ask their patients on CAM use, while government should enact laws regulating CAM use in Nigeria.

African Journal of Environmental Science and Technology, 2017

Proper waste disposal is a key to protecting public health. Thus poorly managed and disposed wast... more Proper waste disposal is a key to protecting public health. Thus poorly managed and disposed waste encourages breeding of insect vectors and exposed public to increase risk of infection. This study aimed at determining the residents' perception about waste disposal in Sokoto metropolis. This was a descriptive cross-sectional survey conducted in Sokoto metropolis. A two stage sampling technique was used to select the survey participants. A set of interviewer-administered questionnaires were used to collect field data. Ethical clearance was obtained from state research ethics committee and in addition, individual informed consent was obtained before questionnaires were administered. Average age of the respondents was 30 years with 50% aged between 25 and 44 years. Large proportion (47.4%) of the respondents had only Quranic education. Majority (94.1%) of the respondents expressed worries about the indiscriminate littering of the metropolis with waste and more than half (55%) reported that residents were responsible for the state of poor sanitation while 38% felt it was fault of government. Although, 91% of respondents said it is appropriate for residents to clean own surroundings, 41% felt residents alone should take sole responsibility for the cleaning; while 40% felt government and residents should take joint responsibility. Less than half (46%) of respondents reported that improper waste disposal have health related problems. Although, majority respondents were disturbed with the way refuse litters the state metropolis, many are unaware of its health related problems. There is need to create awareness among general public of consequences of poor refuse disposal.

Journal of Health Sciences

Research Journal of Pharmacology, 2011

Research Journal of Medical Sciences, 2011

Treatments with cancer chemotherapeutic drugs are often associated with varieties of ADRs. Approp... more Treatments with cancer chemotherapeutic drugs are often associated with varieties of ADRs. Appropriate use of drugs is an essential element in achieving quality of health and medical care for patients and the community as a whole. The objectives of the study were to characterize ADRs associated with anti-cancer chemotherapy and evaluate anti-cancer use pattern and in comparison with the World Health Organization/International Network for Rationale Use of Drugs (WHO/INRUD) core prescribing indicators. A cross sectional retrospective descriptive study conducted at the Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto. The case records of patients were examined and relevant data extracted using a pre-piloted data collection form. Information on demographic and clinical variables, drug use pattern and ADRs were analyzed. WHO/INRUD core prescribing indicators were measured and analyzed. SPSS package version 20 was employed and results displayed in tables and charts. Ethical ap...

Olayiwola Jimoh AG, Toluwalase Bakare H, Tomori Bakare AF. Comparative Analysis of Psychotropic Drugs Prescribing Trends in Two Tertiary Health Institutions North West Nigeria: Investigating Compliance with WHO Core Drug Use Indicators in Health Facilities. Ann Pharmacol Pharm. 2020; 5(2): 1177., 2020

The use of psychotropic medications is common as 7.2% of the world population take at least one o... more The use of psychotropic medications is common as 7.2% of the world population take at least one of such medication. Inappropriate drug prescribing has become a global problem, making drug utilization studies absolutely imperative. Psychotropic drug utilization rates provide information regarding rational drug use and are useful in monitoring treatment for mental disorders on a population basis. The aim of this study therefore was to compare and analyze the pattern of psychotropic drugs prescription, compliance with WHO drug use standards and determine the frequently encountered non-psychotropic's in the psychiatry department of two tertiary health institutions North West Nigeria.

Schwenckia americana belong to the family Solanaceae. it is called Dandana in Hausa (Nigeria). It... more Schwenckia americana belong to the family Solanaceae. it is called Dandana in Hausa (Nigeria). It is used in Hausa traditional medicine to treat arthritis and fungal infections. The result of the phytochemical studies revealed the presence of Saponins, Tannins, Flavonoids, Steroids, Alkaloids and Cardiac glycosides. The antifungal evaluation was carried out using the well diffusion method. Sterile distilled water was used as negative control while ketoconazole was used as the positive control. The concentrations of the plant used were 25 mg/ml, 50 mg/ml and 100mg/ml respectively. At these concentrations, the extract inhibited the growth of Trichophyton mentagrophytes, Microsporum gypseum, and Candida albicans and produced percentage inhition ranging between 62.2% to 80.8%. The antifungal activity demostrated by the plant extract may due to the presence of the phytochemicals presnt in the plant. Therefore, the ethnomedical application of the plant in the treatment of fungal infections in Hausa traditional medicine is justified. INTRODUCTION The use of plants as medicinal agents dates back to the time early man. Plant parts were used by early man in its raw and cooked form to cure various forms illness (Kafaru, 1994). While searching for medicinal plants in north western Nigeria (West Africa), Schwenckia americana was selected due to its ethnomedical applications in Hausa (Nigerian tribe) traditional medicine. In Hausa, it is called Dandana. The plant belongs to the family Solanaceae. According to the renowned herbalist, the crude powdered plant is mixed with fresh fat obtained from cow milk and made into paste. The paste is used to treat arthritis and other forms of pains associated to limbs. The paste is applied topically. The aerial parts are widely valued in West Africa to treat diseases of babies and small children. A leaf decoction is given to pregnant women when the foetus develops too slowly and is taken by breast-feeding women to prevent diarrhoea of the baby (Iwu,1993). The roots are chewed to cure respiratory diseases in children. A root decoction is given to babies as a purgative. An infusion of the aerial parts is used as a mouth wash to cure mouth infections. The plant sap or a decoction of the whole plant is applied as eye drops and nose drops to treat headache, sinusitis and conjunctivitis (Iwu, 1993).

Background: The pain accompanying vaso-occlusive crisis (VOC) in sickle cell disease (SCD) patien... more Background: The pain accompanying vaso-occlusive crisis (VOC) in sickle cell disease (SCD) patients is often severe, but poorly managed in many health care settings. According to the World Health Organisation report, in adequate management, absence of national control programmes, and basic facilities to manage the patients remains a challenge in most countries where sickle-cell anaemia is a major public health concern. Aim: This study aimed to assess the types of therapeutic intervention during hospitalization of sickle cell disease patients presenting with pain-related vaso-occlusive episodes (VOE). Materials and Methods: A cross sectional retrospective review of pain management in vaso-occlusive crises was carried out. Information was obtained from 139 case files of adult sickle cell disease patients managed for VOC in the Haematology unit of the Usmanu Danfodiyo University Teaching Hospital Sokoto from June 2009 to July 2011. Results: The mean age of respondents was 20.07±4.07 ye...

Journal of health science

Background: The state of pregnancy requires that all medications should be prescribed with specif... more Background: The state of pregnancy requires that all medications should be prescribed with specific caution.

Background: There have been reports linking surgical site nosocomial infections with bacteria fro... more Background: There have been reports linking surgical site nosocomial infections with bacteria from the hospital environment. These infections were said to have lead to high morbidity and mortality, Long hospital stays leading to increase in cost of treatment and permanent disability in the affected patients. Data on organisms present in most of the Nigeria hospitals and particularly the theatres are scanty, despite the threat these organisms pose to effective patients’ management. The aim of this work therefore, is to isolate the endemic bacterial type in the theatre of a university teaching hospital in the North West of Nigeria with a view to identifying them and determine their potentials in causing surgical wound infections. Methods: The aerial bacteria in fifteen different points comprise of six theatre suites and a sterile room were trapped by settling plate method, using Nutrient, MacConkey and Blood agar as the culturing media. Plates were incubated aerobically for 24hrs afte...

Background: Regular disinfection of the hospital environment have been the main way by which pres... more Background: Regular disinfection of the hospital environment have been the main way by which presence of microorganisms in the hospital environment are control. But report showed that in many instances this disinfections are mere waste of energy and resources, as the exercise fail to achieve its set objective. Our aim in this work is; testing of effectiveness of four different disinfectants being used in the theatre of the hospital under surveillance in order to establish and recommends appropriate concentration of these disinfectants for use. Methods: Bacterial isolates from the six theatres, a sterile room and other points in the hospital were subjected to different concentrations of the following disinfectants; Izal, Chlohexidine, Povidone iodine and Hypochlorite solution. The concentration of each disinfectant prepared was as recommended by the producers and as being used in the theatre. The test was carried out by using agar ditch method and Mueller Hinton agar was used as susc...

Nigerian Journal of Basic and Applied Sciences, 2011

This study was designed to investigate the effect of Salmonella thyphimurium infection on the pla... more This study was designed to investigate the effect of Salmonella thyphimurium infection on the plasma kinetics of ceftriaxone in Sokoto red goats. In a randomised two-way study, 10 healthy male goats were divided into two groups of five each, and either received a single intramuscular (IM) injection of 1g ceftriaxone only or 1g Ceftriaxone plus inoculation with S. thyphimurium. Non compartmental pharmacokinetic parameters were measured in plasma samples by microbiological assay using Escherichia. coli as the test organism. The pharmacokinetic parameters of Ceftriaxone alone were as follows: absorption half life 0.509±0.004hr, elimination half-life 0.580±0.012hr, maximum plasma concentration (C max ) 45.56±0.191µg/ml, Time to attain C max 0.7±0.123hr, area under the curve(AUC) 144.06±1.711µg-hr/ml, area under mean curve (AUMC) 313.46±6.156µg-hr*hr/ml, volum of distribution (Vd) 485.28±15.725ml/kg, Cl 578.751±6.880ml/hr/kg, MRT 2.18±0.020hr. These were significantly influenced by S. thyphimurium infection; with the absorption half life as 0.318±0.084hr, elimination halflife 0.866±0.113hr, Cmax 41±2.915µg/ml, Tmax 0.5hr, AUC 90.14±2.952µg-hr/ml, AUMC 175.84±6.948µg-hr*hr/ml, Vd 1175.36±181.30ml/kg, clearance 928.549±30.675ml/hr/kg, MRT 1.94±0.060hr . These findings suggest that S. thyphimurium infection in Sokoto red goat significantly influences the pharmacokinetics of Ceftriaxone. Further studies are required to buttress these findings and to establish the mechanism of interaction.

Sahel Medical Journal, 2014

Background: Knowledge and safety perception of physicians concerning commonly used complementary ... more Background: Knowledge and safety perception of physicians concerning commonly used complementary and alternative medicine (CAM) may have influence on decisions of treatment and life of patients. This study determined the knowledge and safety perception of CAM among physicians in an Usmanu Danfodiyo University Teaching Hospital (UDUTH), a tertiary institution in Sokoto, North-Western Nigeria. Materials and Methods: A survey based on an anonymous questionnaire was performed among 221 doctors of UDUTH Sokoto, North-Western Nigeria using a 30-item validated questionnaire to examine their level of awareness and safety perception on CAM. Results: The lifetime prevalence of CAM use among doctors was 69.3% while current CAM use was about 12%. About half (47.5%) of the doctors think CAM use is unsafe. About 84.6%, 86.4%, and 64.3% of doctors think CAM use can cause adverse reactions/side effects, drug interactions, and noncompliance, respectively. Residents/consultants (84.5%) were more likely to correctly identify the standard definitions of CAM compared with house officers/medical officers (77.3%) (P = 0.02). A significantly higher percentage of consultants/residents were found to associate the use of CAM with poor adherence to conventional drugs compared with HO/MO (P = 0.02). Conclusion: This study demonstrates high degree of concern about the safety of CAM as it relates to adverse reactions/side effects, drug interactions, and noncompliance to orthodox medicine among physicians in UDUTH. There was an acceptable level of knowledge of CAM.

Background: Although young adults and college students are the primary target of energy drinks pr... more Background: Although young adults and college students are the primary target of energy drinks producing companies, there has been little studies regarding energy drinks awareness, safety perception and pattern of consumption among students in Nigeria. Objectives: The aim of this research is to determine (i) the prevalence of energy drinks consumption (ii) awareness and the safety perceptions (iii) determinants and pattern of energy drinks consumption among medical students in the college of health sciences, Usmanu Danfodiyo University Sokoto. Methods: A total of 148 students consented to participate in this cross-sectional descriptive study. A pre validated semi structured questionnaire was designed to assess the students’ knowledge of energy drinks, pattern of consumption; including rate and types consumed, frequency of consumption and quantity consumed. The reasons for consumption, perception of safety concerns and side effects associated with the energy drinks. The responses obt...

Pan African Medical Journal, 2016

International Journal of Pharmacy and Pharmaceutical Sciences, Apr 3, 2013

Objective: This study aimed at accessing the pattern of antimalarial prescriptionagainst current ... more Objective: This study aimed at accessing the pattern of antimalarial prescriptionagainst current WHO recommendationand patient affordability of the prescribed antimalarial drug.