Jacó Lavinsky | Universidade Federal do Rio Grande do Sul (original) (raw)

Papers by Jacó Lavinsky

Investigative Ophthalmology & Visual Science, Jul 21, 2020

Ophthalmology, Oct 1, 2014

Rev Hcpa Fac Med Univ Fed Rio Gd Do Sul, Aug 1, 1993

The British journal of ophthalmology, 2014

To assess the rate of pegaptanib-associated sustained intraocular pressure (IOP) elevation. A pos... more To assess the rate of pegaptanib-associated sustained intraocular pressure (IOP) elevation. A posthoc analysis was conducted on all IOP measurements, except the immediate 30-min postinjection, from all subjects randomised to pegaptanib 0.3 mg or sham injections continuously in the first 2 years of the Vascular endothelial growth factor Inhibition Study in Ocular Neovascularisation (V.I.S.I.O.N.) study. Measurements were taken with Goldmann applanation tonometer or Tonopen, except at baseline and in cases of an IOP reading >30 mm Hg when a Goldmann applanation tonometer was mandatory. Of 221 subjects, IOP measurements ≥22 mm Hg were seen in 28/114 and 23/107 subjects of the pegaptanib and sham subgroups, respectively (p=0.6338) and measurements ≥24 mm Hg were observed in eight and eight subjects in the pegaptanib and sham groups, respectively. More than two measurements ≥22 mm Hg occurred in six and 10 subjects (p=0.3025), and more than two measurements ≥24 mm Hg were observed in ...

International Journal of Rehabilitation Research, 2001

This study was designed to evaluate the effectiveness of a contact lens telescopic system in pati... more This study was designed to evaluate the effectiveness of a contact lens telescopic system in patients diagnosed with low Ž. Ž. vision. Fifteen white patients mean age 60.7 years with visual acuity between 20/60 and 20/400 mean 20/245 were Ž. evaluated using first a conventional telescope and subsequently a contact lens telescope CLT. Evaluation parameters were visual acuity, amplitude of visual field, and patients' satisfaction with the systems. The mean final visual acuity attained with both systems was 20/105. No differences in visual acuity between the two systems were detected. However, the visual field was significantly different with each system. Mean visual field with the conventional telescope was 22 degrees, whereas with the CLT it was 52.1 degrees. This corresponds to a reduction of 78.2% in the field of view with the conventional telescope and of 49.5% with the CLT. Therefore, the CLT was found to provide a field of view that is 136% as great as the one provided by the conventional telescope. Younger patients are specially enthusiastic about the CLT because of its improved cosmetic appearance and visual field as compared to traditional telescopes. Aged patients tend to have more difficulty in accepting and using contact lenses daily.

Arq Bras Oftalmol, 2002

Objetivo: Avaliar as complicações pré e pós-vitrectomia, sua correlação com o tempo de permanênci... more Objetivo: Avaliar as complicações pré e pós-vitrectomia, sua correlação com o tempo de permanência do núcleo no vítreo e a acuidade visual final, bem como as complicações a longo prazo. Métodos: Estudo retrospectivo de 12 pacientes que apresentavam fragmentos do cristalino no vítreo pósfacectomia, submetidos a vitrectomia no Serviço de Oftalmologia do Hospital de Clínicas de Porto Alegre (HCPA) entre novembro de 1994 e junho de 2000. Resultados: Após a queda do núcleo no vítreo, 5 pacientes apresentaram edema corneano, 3 uveíte, 8 glaucoma, 1 descolamento de retina e todos tiveram redução da acuidade visual. Submetidos à vitrectomia, no pós-operatório imediato 2 apresentavam hifema, 6 glaucoma, 2 descolamento de retina, 1 phthisis bulbi, 1 edema macular cistóide, 2 perfluorocarbono na câmara anterior e 7 edema corneano. No pós-operatório tardio, a maioria das complicações se resolveram (média de 6 meses). O tempo de permanência do núcleo luxado foi menor que 15 dias para 3 pacientes e maior que 15 dias para 9 pacientes. Conclusão: Os resultados sugerem que os fragmentos do cristalino retidos na cavidade vítrea devem ser removidos prontamente para impedir a resposta inflamatória, melhorando, assim, o prognóstico visual.

Investigative Ophthalmology & Visual Science, Jul 21, 2020

Investigative Ophthalmology & Visual Science, Jun 21, 2021

Fundamentação: a Síndrome de Down (SD) vem sendo objeto de pesquisa desde 1866, quando Sir. Langd... more Fundamentação: a Síndrome de Down (SD) vem sendo objeto de pesquisa desde 1866, quando Sir. Langdon Down a descreveu como uma entidade clínica diferente do cretinismo. A descrição das alterações oculares foi efetuada em 1891 por Oliver. No Brasil a incidência dessa patologia é de 1,13 por 1000 nascidos vivos. Entretanto, são poucos os portadores de síndrome de Down que realizam consultas oftalmológicas periódicas. Objetivos: através da revisão da literatura, estabelecemos as patologias oculares mais freqüentes na síndrome de Down, bem como, os achados oftalmológicos passíveis de prevenção e tratamento, com o objetivo de evitar a perda da acuidade visual. Casuística: foi realizada uma revisão da literatura científica com a busca dos artigos através do pubmed. Foram revisados os artigos que versavam sobre as alterações oftalmológicas em SD, com uma data de publicação entre 1940 e 2002. Foram avaliadas as patologias oculares associadas a SD e as suas freqüências. Resultados: são diversas os achados oculares encontrados em portadores de SD, as mais freqüentes são fissuras palpebrais oblíquas, epicanto, hipertelorismo, blefarite, ceratocone, glaucoma congênito, aumento do número de vaso retinianos, estrabismo, ambliopia, nistagmo e ametropia. Muitas alterações oculares encontradas na SD também o são na população normal, no entanto a freqüência com que ocorrem e a combinação dessas é que as fazem significativas na SD. Conclusões: atualmente, estão sendo criados programas para estimular e motivar a educação de crianças portadoras de SD. O objetivo de introduzi-las na sociedade, e oportunizar uma vida produtiva e útil. Na integração com o ambiente é fundamental a qualidade dos órgãos sensoriais. A preservação de uma visão adequada pode ser obtida com a identificação e tratamento precoce das patologias oculares.

Investigative Ophthalmology & Visual Science, 2014

Clinical Ophthalmology, 2020

Purpose: To evaluate differences in the thickness of the individual macular layers between early,... more Purpose: To evaluate differences in the thickness of the individual macular layers between early, moderate, and severe glaucomatous eyes and compare them with healthy controls. Patients and Methods: Subjects with glaucoma presenting typical optic nerve head findings, high intraocular pressure with or without visual field (VF) damage and normal controls were included. All participants underwent 24-2 perimetry and spectral-domain OCT. Patients were divided into three groups (early, moderate, and severe) based on the mean deviation of the VF and a healthy control group. The device segmented the layers automatically, and their measurements were plotted using the means of the sectors of the inner (3mm) and outer (6mm) circles of the ETDRS grid. Results: A total of 109 eyes qualified for the study: 14 in the control group and 52, 18 and 25 in the early, moderate and severe groups, respectively. Mean age was 66.13 (SD=12.38). The mean thickness of the circumpapillary retinal nerve fiber layer (RNFL), total macular thickness (TMT), macular RNFL, ganglion cell layer (GCL) and inner plexiform layer (IPL) were significantly different between the 4 groups, with progressive decrease in thickness. Significant overall difference was found for the inner nuclear layer (INL), and the severe glaucoma group presented thicker measurements than controls and early glaucoma. Outer nuclear layer (ONL) was thinner in severe glaucoma group compared with early glaucoma group. Conclusion: Individual macular layer measurement using the inner and outer circles of the ETDRS grid is useful to evaluate different stages of glaucoma. The INL thickening and ONL thinning in advanced glaucoma should be explored in the future studies.

Clinical ophthalmology (Auckland, N.Z.), 2018

To evaluate the hypotenuse of the vertical optic nerve head cup (HVOC), measured using the length... more To evaluate the hypotenuse of the vertical optic nerve head cup (HVOC), measured using the length and depth of the cup obtained with enhanced depth imaging spectral-domain optic coherence tomography (SD-OCT), as a biomarker for glaucoma diagnosis. This was a prospective cross-sectional study of patients with glaucoma and controls. SD-OCT was performed in all participants to assess average circumpapillary retinal nerve fiber layer (RNFL) thickness. A vertical B-scan of the optic nerve head (ONH) was obtained for HVOC measurement. The length and depth of the optic nerve cup formed the sides of a right triangle that were used to calculate the HVOC. Participants also underwent standard automated perimetry. One hundred and fifty-six eyes were divided into three groups: mean deviation (MD) <-7 dB (60 eyes); MD ≥-7 dB (74 eyes); and healthy subjects (22 eyes). The mean (SD) HVOC in these groups was 1,419.8 (347.2) µm, 1,234.6 (258.8) µm, and 685.79 (315.4) µm (<0.01), respectively. I...

Investigative Ophthalmology & Visual Science, Jul 21, 2020

Ophthalmology, Oct 1, 2014

Rev Hcpa Fac Med Univ Fed Rio Gd Do Sul, Aug 1, 1993

The British journal of ophthalmology, 2014

To assess the rate of pegaptanib-associated sustained intraocular pressure (IOP) elevation. A pos... more To assess the rate of pegaptanib-associated sustained intraocular pressure (IOP) elevation. A posthoc analysis was conducted on all IOP measurements, except the immediate 30-min postinjection, from all subjects randomised to pegaptanib 0.3 mg or sham injections continuously in the first 2 years of the Vascular endothelial growth factor Inhibition Study in Ocular Neovascularisation (V.I.S.I.O.N.) study. Measurements were taken with Goldmann applanation tonometer or Tonopen, except at baseline and in cases of an IOP reading >30 mm Hg when a Goldmann applanation tonometer was mandatory. Of 221 subjects, IOP measurements ≥22 mm Hg were seen in 28/114 and 23/107 subjects of the pegaptanib and sham subgroups, respectively (p=0.6338) and measurements ≥24 mm Hg were observed in eight and eight subjects in the pegaptanib and sham groups, respectively. More than two measurements ≥22 mm Hg occurred in six and 10 subjects (p=0.3025), and more than two measurements ≥24 mm Hg were observed in ...

International Journal of Rehabilitation Research, 2001

This study was designed to evaluate the effectiveness of a contact lens telescopic system in pati... more This study was designed to evaluate the effectiveness of a contact lens telescopic system in patients diagnosed with low Ž. Ž. vision. Fifteen white patients mean age 60.7 years with visual acuity between 20/60 and 20/400 mean 20/245 were Ž. evaluated using first a conventional telescope and subsequently a contact lens telescope CLT. Evaluation parameters were visual acuity, amplitude of visual field, and patients' satisfaction with the systems. The mean final visual acuity attained with both systems was 20/105. No differences in visual acuity between the two systems were detected. However, the visual field was significantly different with each system. Mean visual field with the conventional telescope was 22 degrees, whereas with the CLT it was 52.1 degrees. This corresponds to a reduction of 78.2% in the field of view with the conventional telescope and of 49.5% with the CLT. Therefore, the CLT was found to provide a field of view that is 136% as great as the one provided by the conventional telescope. Younger patients are specially enthusiastic about the CLT because of its improved cosmetic appearance and visual field as compared to traditional telescopes. Aged patients tend to have more difficulty in accepting and using contact lenses daily.

Arq Bras Oftalmol, 2002

Objetivo: Avaliar as complicações pré e pós-vitrectomia, sua correlação com o tempo de permanênci... more Objetivo: Avaliar as complicações pré e pós-vitrectomia, sua correlação com o tempo de permanência do núcleo no vítreo e a acuidade visual final, bem como as complicações a longo prazo. Métodos: Estudo retrospectivo de 12 pacientes que apresentavam fragmentos do cristalino no vítreo pósfacectomia, submetidos a vitrectomia no Serviço de Oftalmologia do Hospital de Clínicas de Porto Alegre (HCPA) entre novembro de 1994 e junho de 2000. Resultados: Após a queda do núcleo no vítreo, 5 pacientes apresentaram edema corneano, 3 uveíte, 8 glaucoma, 1 descolamento de retina e todos tiveram redução da acuidade visual. Submetidos à vitrectomia, no pós-operatório imediato 2 apresentavam hifema, 6 glaucoma, 2 descolamento de retina, 1 phthisis bulbi, 1 edema macular cistóide, 2 perfluorocarbono na câmara anterior e 7 edema corneano. No pós-operatório tardio, a maioria das complicações se resolveram (média de 6 meses). O tempo de permanência do núcleo luxado foi menor que 15 dias para 3 pacientes e maior que 15 dias para 9 pacientes. Conclusão: Os resultados sugerem que os fragmentos do cristalino retidos na cavidade vítrea devem ser removidos prontamente para impedir a resposta inflamatória, melhorando, assim, o prognóstico visual.

Investigative Ophthalmology & Visual Science, Jul 21, 2020

Investigative Ophthalmology & Visual Science, Jun 21, 2021

Fundamentação: a Síndrome de Down (SD) vem sendo objeto de pesquisa desde 1866, quando Sir. Langd... more Fundamentação: a Síndrome de Down (SD) vem sendo objeto de pesquisa desde 1866, quando Sir. Langdon Down a descreveu como uma entidade clínica diferente do cretinismo. A descrição das alterações oculares foi efetuada em 1891 por Oliver. No Brasil a incidência dessa patologia é de 1,13 por 1000 nascidos vivos. Entretanto, são poucos os portadores de síndrome de Down que realizam consultas oftalmológicas periódicas. Objetivos: através da revisão da literatura, estabelecemos as patologias oculares mais freqüentes na síndrome de Down, bem como, os achados oftalmológicos passíveis de prevenção e tratamento, com o objetivo de evitar a perda da acuidade visual. Casuística: foi realizada uma revisão da literatura científica com a busca dos artigos através do pubmed. Foram revisados os artigos que versavam sobre as alterações oftalmológicas em SD, com uma data de publicação entre 1940 e 2002. Foram avaliadas as patologias oculares associadas a SD e as suas freqüências. Resultados: são diversas os achados oculares encontrados em portadores de SD, as mais freqüentes são fissuras palpebrais oblíquas, epicanto, hipertelorismo, blefarite, ceratocone, glaucoma congênito, aumento do número de vaso retinianos, estrabismo, ambliopia, nistagmo e ametropia. Muitas alterações oculares encontradas na SD também o são na população normal, no entanto a freqüência com que ocorrem e a combinação dessas é que as fazem significativas na SD. Conclusões: atualmente, estão sendo criados programas para estimular e motivar a educação de crianças portadoras de SD. O objetivo de introduzi-las na sociedade, e oportunizar uma vida produtiva e útil. Na integração com o ambiente é fundamental a qualidade dos órgãos sensoriais. A preservação de uma visão adequada pode ser obtida com a identificação e tratamento precoce das patologias oculares.

Investigative Ophthalmology & Visual Science, 2014

Clinical Ophthalmology, 2020

Purpose: To evaluate differences in the thickness of the individual macular layers between early,... more Purpose: To evaluate differences in the thickness of the individual macular layers between early, moderate, and severe glaucomatous eyes and compare them with healthy controls. Patients and Methods: Subjects with glaucoma presenting typical optic nerve head findings, high intraocular pressure with or without visual field (VF) damage and normal controls were included. All participants underwent 24-2 perimetry and spectral-domain OCT. Patients were divided into three groups (early, moderate, and severe) based on the mean deviation of the VF and a healthy control group. The device segmented the layers automatically, and their measurements were plotted using the means of the sectors of the inner (3mm) and outer (6mm) circles of the ETDRS grid. Results: A total of 109 eyes qualified for the study: 14 in the control group and 52, 18 and 25 in the early, moderate and severe groups, respectively. Mean age was 66.13 (SD=12.38). The mean thickness of the circumpapillary retinal nerve fiber layer (RNFL), total macular thickness (TMT), macular RNFL, ganglion cell layer (GCL) and inner plexiform layer (IPL) were significantly different between the 4 groups, with progressive decrease in thickness. Significant overall difference was found for the inner nuclear layer (INL), and the severe glaucoma group presented thicker measurements than controls and early glaucoma. Outer nuclear layer (ONL) was thinner in severe glaucoma group compared with early glaucoma group. Conclusion: Individual macular layer measurement using the inner and outer circles of the ETDRS grid is useful to evaluate different stages of glaucoma. The INL thickening and ONL thinning in advanced glaucoma should be explored in the future studies.

Clinical ophthalmology (Auckland, N.Z.), 2018

To evaluate the hypotenuse of the vertical optic nerve head cup (HVOC), measured using the length... more To evaluate the hypotenuse of the vertical optic nerve head cup (HVOC), measured using the length and depth of the cup obtained with enhanced depth imaging spectral-domain optic coherence tomography (SD-OCT), as a biomarker for glaucoma diagnosis. This was a prospective cross-sectional study of patients with glaucoma and controls. SD-OCT was performed in all participants to assess average circumpapillary retinal nerve fiber layer (RNFL) thickness. A vertical B-scan of the optic nerve head (ONH) was obtained for HVOC measurement. The length and depth of the optic nerve cup formed the sides of a right triangle that were used to calculate the HVOC. Participants also underwent standard automated perimetry. One hundred and fifty-six eyes were divided into three groups: mean deviation (MD) <-7 dB (60 eyes); MD ≥-7 dB (74 eyes); and healthy subjects (22 eyes). The mean (SD) HVOC in these groups was 1,419.8 (347.2) µm, 1,234.6 (258.8) µm, and 685.79 (315.4) µm (<0.01), respectively. I...