Sukardiman Harjotaruno | Universitas Airlangga (original) (raw)
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Graduate Center of the City University of New York
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Papers by Sukardiman Harjotaruno
African Journal of Traditional, Complementary and Alternative Medicines, 2008
Andrographolide isolated from Andrographis paniculata Ness (Acanthaceae) at 0.35 mM , 0.70 mM and... more Andrographolide isolated from Andrographis paniculata Ness (Acanthaceae) at 0.35 mM , 0.70 mM and 1.40 mM induced DNA fragmentation and increased the percentage of apoptotic cells when TD-47 human breast cancer cell line was treated for 24 , 48 and 72 h. The results demonstrated that andrographolide can induce apoptosis in TD-47 human breast cancer cell line in a time and concentration-dependent manner by increase expression of p53, bax , caspase-3 and decrease expression of bcl-2 determined by immunohistochemical analysis.
African Journal of Traditional, Complementary and Alternative Medicines, 2008
Andrographolide isolated from Andrographis paniculata Ness (Acanthaceae) at 0.35 mM , 0.70 mM and... more Andrographolide isolated from Andrographis paniculata Ness (Acanthaceae) at 0.35 mM , 0.70 mM and 1.40 mM induced DNA fragmentation and increased the percentage of apoptotic cells when TD-47 human breast cancer cell line was treated for 24 , 48 and 72 h. The results demonstrated that andrographolide can induce apoptosis in TD-47 human breast cancer cell line in a time and concentration-dependent manner by increase expression of p53, bax , caspase-3 and decrease expression of bcl-2 determined by immunohistochemical analysis.