Manjusha jindal | Goa University (original) (raw)
Papers by Manjusha jindal
International Journal of Clinical Obstetrics and Gynaecology
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
Indian Obstetrics and Gynaecology, Mar 31, 2013
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common... more Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common cancer among women (Age standaradised incidence rate being 6.6/100,000) and seventh leading cause of cancer deaths globally (age standaradised mortality rate being 4.0/100,00). 1 In India, during the period 2004-2005, proportion of ovarian cancer varied from 1.7% to 8.7% of all female cancers in various population based registries of Indian Council of Medical Research. The proportion of this cancer was 6.0%-7.7% of all cancers among females in Gujarat. The Age Specific Incidence Rate (ASIR) for ovarian cancer revealed that the disease increases from 35 years of age and reaches a peak between the ages 55-64. 2 Late presentation and ineffective screening methods are impediments in its early detection. The screening tests in form of estimation of CA-125 and Transvaginal sonography are non-specific. 3 Therefore, the diagnosis is made in late stage when cure rates are low and with increased morbidity due to limited effective treatment options. Five-year survival rates range from 30-50% for all ABSTRACT Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research. Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors. Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first line treatment in 35%. The mean age at diagnosis was more with advancing stage (stage one 44±9.53 and stage four 55.35±9.74 years) but it was not statistically significant (p=0.098) Advancing age demonstrated poor survival (log-rank p=0.05) but survival was not significantly different in relation to histopathology (log-rank =0.629). On multivariate regression analysis age of patient (p=0.004), and stage of disease (p=0.005) were found to be independent risk factors while histopathology was not an independent risk factor (p=0.688) for survival. Conclusions: Research should be aimed to find tools for screening and early diagnosis as well as better therapeutic approaches for advanced epithelial ovarian cancer.
A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning bet... more A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning between Jan 4 to Dec 13 regarding Maternal Mortality. Results: There were total of 58 deaths out of 54604 live births during this 10 year period giving maternal mortality ratio(MMR) of 106.15/ 100000 live births which is 50% less as compared to MMR in India(212 maternal deaths/100,000 live births). In last 2 years i.e. in 2012 and 2013 it has come down 86.35-94.46 maternal deaths/100,000 live births, thus already reaching MDG 5 of WHO Referral cases accounted 87.85%. The majority of cases were in 21-30 year age group (93.2%) and mostly they were primigravida (55.1%). Hemorrhage (29cases) was the commonest cause of death followed by pregnancy induced hypertension (26cases). Conclusion: Hemorrhage (PPH, accidental hemorrhage, ruptured uterus), pregnancy induced hypertension including eclampsia, HELP Syndrome, Sepsis and DIC were found to be the direct major causes of death. Anaemia, cardiac disease, hepatitis etc. were other indirect causes of death. So if India has to achieve Millennium Development Goal of slashing the MMR by three quarters by 2015 then determinants of maternal mortality need to be identified and tackled on priority basis. Sustained reduction in maternal mortality will only be possible if modern high quality obstetric care is made available to all women through a system of professional midwifery and referral hospital care in the context of political commitment and accountability of health providers.
Background: Hysterectomy (removal of uterus) has many indications like fibroids, dysfunctional ut... more Background: Hysterectomy (removal of uterus) has many indications like fibroids, dysfunctional uterine bleeding, uterine prolapse and chronic pelvic pain. The purpose of this study is to know the level of awareness of women about hysterectomy, to study their experiences, to assess their involvement in decision making process and to develop a suitable protocol, counselling and education material to ensure women's involvement. Methods: This is a cross sectional study using validated semi-structured interview questionnaire over 6 months (1st December, 2018 to 31st May, 2019) in Goa Medical College. Data was entered in epidata manager and analysed using SPSS 22 version. Categorical variables were expressed in percentages and proportions and quantitative variables in mean±SD. Significance was checked using Chi square test and association between dependent and independent variables was assessed by using bivariate analysis. P value <0.05 was taken as significant. Results: A total of 149 women were recruited into the study who were admitted for hysterectomy. The mean age of women was 49.3 years. The awareness with respect to various aspects of hysterectomy was good in 23.4% subjects and poor in 76.6% subjects. The awareness was significantly related to level of education (p=0.002), urban location (p=0.016) and socioeconomic status (p=0.028). Education was significant factor in decision-making process (p< 0.05). It was observed that good experience had positive correlation to their perception about hysterectomy. Conclusions: It was concluded that awareness about hysterectomy was significantly related to education, urban location and socioeconomic status of women. Pre-operative education would help to reduce the post-operative symptoms for a women undergoing hysterectomy.
Background: Low birth weight (LBW) is an important public health problem in India significantly c... more Background: Low birth weight (LBW) is an important public health problem in India significantly contribu ng to increased morbidity and mortality among infants and young children. The aims and objec ves of our study were to assess the magnitude of LBW and socio-cultural factors influencing LBW among babies delivered at Goa Medical College. This would in turn provide evidence to improve foeto-maternal well-being. Materials and methods: This hospital based prospec ve longitudinal study was conducted at Goa Medical College, Bambolim-Goa. A total of 200 inpa ent pregnant mothers who delivered at GMC (100 with low birth weight and 100 with normal birth weight babies) between December 2018 to March 2019 were included in this study by consecu ve sampling. Data was collected on a predesigned, standardised, structured ques onnaire by direct interview of the consen ng mothers. The data was analyzed using SPSS version 22. It was expressed in mean, percentage and propor ons with standard devia on. Chi-square test was used to find out the associa on between various categorical variables (p < 0.05 was considered significant). Binary logis c regression analysis was done for significant variables to iden fy independent predictors of LBW. Results: The study concluded that age of the mother (OD ra o 17.771), type of family (p value < 0.05), socioeconomic status, educa onal status of mother, occupa on of mother, anaemia and lack of iron and folic acid supplements (IFA) had significant effect on LBW (p value < 0.05). Conclusion: As the problem of LBW is mul-dimensional, an integrated approach incorpora ng medical, social, economical and educa onal measures are necessary for preven on of LBW.
A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning bet... more A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning between Jan 4 to Dec 13 regarding Maternal Mortality. Results: There were total of 58 deaths out of 54604 live births during this 10 year period giving maternal mortality ratio(MMR) of 106.15/ 100000 live births which is 50% less as compared to MMR in India(212 maternal deaths/100,000 live births). In last 2 years i.e. in 2012 and 2013 it has come down 86.35-94.46 maternal deaths/100,000 live births, thus already reaching MDG 5 of WHO Referral cases accounted 87.85%. The majority of cases were in 21-30 year age group (93.2%) and mostly they were primigravida (55.1%). Hemorrhage (29cases) was the commonest cause of death followed by pregnancy induced hypertension (26cases). Conclusion: Hemorrhage (PPH, accidental hemorrhage, ruptured uterus), pregnancy induced hypertension including eclampsia, HELP Syndrome, Sepsis and DIC were found to be the direct major causes of death. Anaemia, cardiac disease, hepatitis etc. were other indirect causes of death. So if India has to achieve Millennium Development Goal of slashing the MMR by three quarters by 2015 then determinants of maternal mortality need to be identified and tackled on priority basis. Sustained reduction in maternal mortality will only be possible if modern high quality obstetric care is made available to all women through a system of professional midwifery and referral hospital care in the context of political commitment and accountability of health providers.
Mobile: 9423819600 and 34 million in the developing countries suffering from lifetime infertility... more Mobile: 9423819600 and 34 million in the developing countries suffering from lifetime infertility according to WHO 2010 census 1. In India, primary infertility ranges between 3.9 to 16.8%, prevalence varying in various states. 2
International journal of scientific research, 2021
Introduction: (1) The female genital tract is constituted by the ovaries, fallopian tubes, uterus... more Introduction: (1) The female genital tract is constituted by the ovaries, fallopian tubes, uterus (body/corpus and cervix), vagina, and vulva. Female genital tract lesions can be benign or malignant. Our study was carried out to nd out the frequency of various histopathological lesions including neoplasms of female genital tract. Materials and Methods: Our study is retrospective conducted over 2 years period. Data was collected from case records of patients presenting to Goa Medical College and histopathology reports obtained from Dept of pathology. Data was represented in form of charts and tables. The analysis of statistical data of variables was done using SPSS software version 22. Signicance was calculated using chi square test. Value of p <0.05 was considered signicant. Results: Out of total 270 subjects studied, 229 were having benign lesions and 41 had malignant lesions.The mean age was 49.5 years. Leiomyoma was diagnosed in (40.58%) cases. In abnormalities of endometri...
All over the World, hysterectomy is the most common surgery in women next only to Caesarean secti... more All over the World, hysterectomy is the most common surgery in women next only to Caesarean section. There is a huge variation in the rate of hysterectomy in various parts of the world. Hysterectomy prevalence was found to be 0.2-6.3 per 100 women in age group 15-49 years for 21 out of 36 states and Union Territories of India as per study done by Prusty et al. The importance of providing detailed information about treatment options to patients and also participation of patients in treatment decision making is being stressed upon by the governmental, health professional and health care provider organisations. Hysterectomy is associated with various psychosocial effects in context to pain experienced, sexual functioning and pre-operative as well as postoperative anxiety. Operative procedure can be physically ABSTRACT
Indian Journal of Obstetrics and Gynecology Research
The most common complication in pregnancy is Hypertension complicating 12-22% of all pregnancies.... more The most common complication in pregnancy is Hypertension complicating 12-22% of all pregnancies. Among these pre-eclampsia is the leading cause constituting 10% of all pregnancies worldwide. In hospital practice in India, the incidence of pre-eclampsia varies from 5% to 15% and of eclampsia about 1.5%. According to WHO report 2008, eclampsia constitutes for 12% of all maternal deaths in developing countries. Thus it is important to study its Epidemiology and Management strategies. Retrospective descriptive data based study. The data is collected after reviewing the medical records of all gravid women with hypertensive disorder of pregnancy who presented between July 2010–July 2014. Data was collected on predesigned, standardised proforma of National Eclampsia Registry. Statistical analysis was performed using SPSS version 22. Data was expressed as Mean, percentages, proportions. Chi-square test was used to find association between various categorical variables. p-value <0.05 was...
International Journal of Medical Science and Public Health
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Ovarian neoplasms are a distinct entity in women health care and are increasingly con... more Background: Ovarian neoplasms are a distinct entity in women health care and are increasingly contributing to morbidity and mortality among women. The burden is not only related to the increasing incidence but also to the varied pathological features depending on the tissue of origin and pathogenesis. The study was carried out to find the prevalence and determine the clinical presentation and histo-pathological distribution of ovarian neoplasms. Management options were also noted.Methods: It is a retrospective study carried out at Goa Medical College between January 2013 to December 2015. All patients diagnosed and treated for ovarian neoplasm were included in the study. Data was tabulated using Microsoft Excel and descriptive statistical analysis was carried out using SPSS version 23.Results: A total of 3111 patients were admitted in gynecology at Goa Medical College during the specified time period. Of these 358 cases were diagnosed with ovarian neoplasm. On histopathology 196 wer...
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Management of Term Prelabour Rupture of Membranes (PROM) remains a matter of debate de... more BACKGROUND Management of Term Prelabour Rupture of Membranes (PROM) remains a matter of debate despite exhaustive research. Aims and Objectives-The objective of this study was to compare use of Tab. Misoprostol per vaginum versus Oxytocin infusion in PROM at term with respect to induction-delivery interval and maternal and foetal outcome. MATERIALS AND METHODS The present study was descriptive comparative study of Tab. Misoprostol (Group A) and Oxytocin infusion (Group B) for induction of labour in PROM at term. The study population consisted of 140 patients. RESULTS Mean induction delivery interval in present study was 541.06 ± 186 minutes in Group A and 556.69 + 219.54 minutes in Group B (p= 0.418), showing no significant difference between two groups. 8.6% women in Group A and 2.9% in Group B had hyperstimulation with no significant difference between the two. There was no significant difference in neonatal complications in the two groups. CONCLUSION The incidences of maternal and foetal untoward effects are similar with use of the two inducing agents with no significant difference in induction delivery interval. Vaginal administration of Misoprostol in a dose of 25 µg 6 hourly to maximum of four doses is an effective alternative of oxytocin for labour induction in term PROM, especially in low resource setups where storage facility for oxytocin and skilled staff for its titration is not available.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in ... more Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research.Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors.Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first ...
A Case of Abdominal Scar Endometriosis a Rare Entity and Review of Literature, Oct 8, 2013
Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common... more Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common cancer among women (Age standaradised incidence rate being 6.6/100,000) and seventh leading cause of cancer deaths globally (age standaradised mortality rate being 4.0/100,00). 1 In India, during the period 2004-2005, proportion of ovarian cancer varied from 1.7% to 8.7% of all female cancers in various population based registries of Indian Council of Medical Research. The proportion of this cancer was 6.0%-7.7% of all cancers among females in Gujarat. The Age Specific Incidence Rate (ASIR) for ovarian cancer revealed that the disease increases from 35 years of age and reaches a peak between the ages 55-64. 2 Late presentation and ineffective screening methods are impediments in its early detection. The screening tests in form of estimation of CA-125 and Transvaginal sonography are non-specific. 3 Therefore, the diagnosis is made in late stage when cure rates are low and with increased morbidity due to limited effective treatment options. Five-year survival rates range from 30-50% for all ABSTRACT Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research. Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors. Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first line treatment in 35%. The mean age at diagnosis was more with advancing stage (stage one 44±9.53 and stage four 55.35±9.74 years) but it was not statistically significant (p=0.098) Advancing age demonstrated poor survival (log-rank p=0.05) but survival was not significantly different in relation to histopathology (log-rank =0.629). On multivariate regression analysis age of patient (p=0.004), and stage of disease (p=0.005) were found to be independent risk factors while histopathology was not an independent risk factor (p=0.688) for survival. Conclusions: Research should be aimed to find tools for screening and early diagnosis as well as better therapeutic approaches for advanced epithelial ovarian cancer.
International Journal of Clinical Obstetrics and Gynaecology
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
Indian Obstetrics and Gynaecology, Mar 31, 2013
It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. ... more It is rare to find retained dead fetal skeleton presenting with the symptom of menometrorrhagia. The usual presentation is in form of missed abortion or incomplete abortion. If fetal bones in utero get retained and mummified, it causes infertility or osseous metaplasia. In our case a perimenopausal lady presented with irregular bleeding, the diagnosis was made with hysteroscopy. In order to bring awareness regarding this symptom the present case is presented and the literature reviewed with respect to endometrial ossification following retained products of conception.
Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common... more Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common cancer among women (Age standaradised incidence rate being 6.6/100,000) and seventh leading cause of cancer deaths globally (age standaradised mortality rate being 4.0/100,00). 1 In India, during the period 2004-2005, proportion of ovarian cancer varied from 1.7% to 8.7% of all female cancers in various population based registries of Indian Council of Medical Research. The proportion of this cancer was 6.0%-7.7% of all cancers among females in Gujarat. The Age Specific Incidence Rate (ASIR) for ovarian cancer revealed that the disease increases from 35 years of age and reaches a peak between the ages 55-64. 2 Late presentation and ineffective screening methods are impediments in its early detection. The screening tests in form of estimation of CA-125 and Transvaginal sonography are non-specific. 3 Therefore, the diagnosis is made in late stage when cure rates are low and with increased morbidity due to limited effective treatment options. Five-year survival rates range from 30-50% for all ABSTRACT Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research. Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors. Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first line treatment in 35%. The mean age at diagnosis was more with advancing stage (stage one 44±9.53 and stage four 55.35±9.74 years) but it was not statistically significant (p=0.098) Advancing age demonstrated poor survival (log-rank p=0.05) but survival was not significantly different in relation to histopathology (log-rank =0.629). On multivariate regression analysis age of patient (p=0.004), and stage of disease (p=0.005) were found to be independent risk factors while histopathology was not an independent risk factor (p=0.688) for survival. Conclusions: Research should be aimed to find tools for screening and early diagnosis as well as better therapeutic approaches for advanced epithelial ovarian cancer.
A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning bet... more A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning between Jan 4 to Dec 13 regarding Maternal Mortality. Results: There were total of 58 deaths out of 54604 live births during this 10 year period giving maternal mortality ratio(MMR) of 106.15/ 100000 live births which is 50% less as compared to MMR in India(212 maternal deaths/100,000 live births). In last 2 years i.e. in 2012 and 2013 it has come down 86.35-94.46 maternal deaths/100,000 live births, thus already reaching MDG 5 of WHO Referral cases accounted 87.85%. The majority of cases were in 21-30 year age group (93.2%) and mostly they were primigravida (55.1%). Hemorrhage (29cases) was the commonest cause of death followed by pregnancy induced hypertension (26cases). Conclusion: Hemorrhage (PPH, accidental hemorrhage, ruptured uterus), pregnancy induced hypertension including eclampsia, HELP Syndrome, Sepsis and DIC were found to be the direct major causes of death. Anaemia, cardiac disease, hepatitis etc. were other indirect causes of death. So if India has to achieve Millennium Development Goal of slashing the MMR by three quarters by 2015 then determinants of maternal mortality need to be identified and tackled on priority basis. Sustained reduction in maternal mortality will only be possible if modern high quality obstetric care is made available to all women through a system of professional midwifery and referral hospital care in the context of political commitment and accountability of health providers.
Background: Hysterectomy (removal of uterus) has many indications like fibroids, dysfunctional ut... more Background: Hysterectomy (removal of uterus) has many indications like fibroids, dysfunctional uterine bleeding, uterine prolapse and chronic pelvic pain. The purpose of this study is to know the level of awareness of women about hysterectomy, to study their experiences, to assess their involvement in decision making process and to develop a suitable protocol, counselling and education material to ensure women's involvement. Methods: This is a cross sectional study using validated semi-structured interview questionnaire over 6 months (1st December, 2018 to 31st May, 2019) in Goa Medical College. Data was entered in epidata manager and analysed using SPSS 22 version. Categorical variables were expressed in percentages and proportions and quantitative variables in mean±SD. Significance was checked using Chi square test and association between dependent and independent variables was assessed by using bivariate analysis. P value <0.05 was taken as significant. Results: A total of 149 women were recruited into the study who were admitted for hysterectomy. The mean age of women was 49.3 years. The awareness with respect to various aspects of hysterectomy was good in 23.4% subjects and poor in 76.6% subjects. The awareness was significantly related to level of education (p=0.002), urban location (p=0.016) and socioeconomic status (p=0.028). Education was significant factor in decision-making process (p< 0.05). It was observed that good experience had positive correlation to their perception about hysterectomy. Conclusions: It was concluded that awareness about hysterectomy was significantly related to education, urban location and socioeconomic status of women. Pre-operative education would help to reduce the post-operative symptoms for a women undergoing hysterectomy.
Background: Low birth weight (LBW) is an important public health problem in India significantly c... more Background: Low birth weight (LBW) is an important public health problem in India significantly contribu ng to increased morbidity and mortality among infants and young children. The aims and objec ves of our study were to assess the magnitude of LBW and socio-cultural factors influencing LBW among babies delivered at Goa Medical College. This would in turn provide evidence to improve foeto-maternal well-being. Materials and methods: This hospital based prospec ve longitudinal study was conducted at Goa Medical College, Bambolim-Goa. A total of 200 inpa ent pregnant mothers who delivered at GMC (100 with low birth weight and 100 with normal birth weight babies) between December 2018 to March 2019 were included in this study by consecu ve sampling. Data was collected on a predesigned, standardised, structured ques onnaire by direct interview of the consen ng mothers. The data was analyzed using SPSS version 22. It was expressed in mean, percentage and propor ons with standard devia on. Chi-square test was used to find out the associa on between various categorical variables (p < 0.05 was considered significant). Binary logis c regression analysis was done for significant variables to iden fy independent predictors of LBW. Results: The study concluded that age of the mother (OD ra o 17.771), type of family (p value < 0.05), socioeconomic status, educa onal status of mother, occupa on of mother, anaemia and lack of iron and folic acid supplements (IFA) had significant effect on LBW (p value < 0.05). Conclusion: As the problem of LBW is mul-dimensional, an integrated approach incorpora ng medical, social, economical and educa onal measures are necessary for preven on of LBW.
A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning bet... more A retrospective study was conducted in the Dept. of OBG GMC over a period of10 years spanning between Jan 4 to Dec 13 regarding Maternal Mortality. Results: There were total of 58 deaths out of 54604 live births during this 10 year period giving maternal mortality ratio(MMR) of 106.15/ 100000 live births which is 50% less as compared to MMR in India(212 maternal deaths/100,000 live births). In last 2 years i.e. in 2012 and 2013 it has come down 86.35-94.46 maternal deaths/100,000 live births, thus already reaching MDG 5 of WHO Referral cases accounted 87.85%. The majority of cases were in 21-30 year age group (93.2%) and mostly they were primigravida (55.1%). Hemorrhage (29cases) was the commonest cause of death followed by pregnancy induced hypertension (26cases). Conclusion: Hemorrhage (PPH, accidental hemorrhage, ruptured uterus), pregnancy induced hypertension including eclampsia, HELP Syndrome, Sepsis and DIC were found to be the direct major causes of death. Anaemia, cardiac disease, hepatitis etc. were other indirect causes of death. So if India has to achieve Millennium Development Goal of slashing the MMR by three quarters by 2015 then determinants of maternal mortality need to be identified and tackled on priority basis. Sustained reduction in maternal mortality will only be possible if modern high quality obstetric care is made available to all women through a system of professional midwifery and referral hospital care in the context of political commitment and accountability of health providers.
Mobile: 9423819600 and 34 million in the developing countries suffering from lifetime infertility... more Mobile: 9423819600 and 34 million in the developing countries suffering from lifetime infertility according to WHO 2010 census 1. In India, primary infertility ranges between 3.9 to 16.8%, prevalence varying in various states. 2
International journal of scientific research, 2021
Introduction: (1) The female genital tract is constituted by the ovaries, fallopian tubes, uterus... more Introduction: (1) The female genital tract is constituted by the ovaries, fallopian tubes, uterus (body/corpus and cervix), vagina, and vulva. Female genital tract lesions can be benign or malignant. Our study was carried out to nd out the frequency of various histopathological lesions including neoplasms of female genital tract. Materials and Methods: Our study is retrospective conducted over 2 years period. Data was collected from case records of patients presenting to Goa Medical College and histopathology reports obtained from Dept of pathology. Data was represented in form of charts and tables. The analysis of statistical data of variables was done using SPSS software version 22. Signicance was calculated using chi square test. Value of p <0.05 was considered signicant. Results: Out of total 270 subjects studied, 229 were having benign lesions and 41 had malignant lesions.The mean age was 49.5 years. Leiomyoma was diagnosed in (40.58%) cases. In abnormalities of endometri...
All over the World, hysterectomy is the most common surgery in women next only to Caesarean secti... more All over the World, hysterectomy is the most common surgery in women next only to Caesarean section. There is a huge variation in the rate of hysterectomy in various parts of the world. Hysterectomy prevalence was found to be 0.2-6.3 per 100 women in age group 15-49 years for 21 out of 36 states and Union Territories of India as per study done by Prusty et al. The importance of providing detailed information about treatment options to patients and also participation of patients in treatment decision making is being stressed upon by the governmental, health professional and health care provider organisations. Hysterectomy is associated with various psychosocial effects in context to pain experienced, sexual functioning and pre-operative as well as postoperative anxiety. Operative procedure can be physically ABSTRACT
Indian Journal of Obstetrics and Gynecology Research
The most common complication in pregnancy is Hypertension complicating 12-22% of all pregnancies.... more The most common complication in pregnancy is Hypertension complicating 12-22% of all pregnancies. Among these pre-eclampsia is the leading cause constituting 10% of all pregnancies worldwide. In hospital practice in India, the incidence of pre-eclampsia varies from 5% to 15% and of eclampsia about 1.5%. According to WHO report 2008, eclampsia constitutes for 12% of all maternal deaths in developing countries. Thus it is important to study its Epidemiology and Management strategies. Retrospective descriptive data based study. The data is collected after reviewing the medical records of all gravid women with hypertensive disorder of pregnancy who presented between July 2010–July 2014. Data was collected on predesigned, standardised proforma of National Eclampsia Registry. Statistical analysis was performed using SPSS version 22. Data was expressed as Mean, percentages, proportions. Chi-square test was used to find association between various categorical variables. p-value <0.05 was...
International Journal of Medical Science and Public Health
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Ovarian neoplasms are a distinct entity in women health care and are increasingly con... more Background: Ovarian neoplasms are a distinct entity in women health care and are increasingly contributing to morbidity and mortality among women. The burden is not only related to the increasing incidence but also to the varied pathological features depending on the tissue of origin and pathogenesis. The study was carried out to find the prevalence and determine the clinical presentation and histo-pathological distribution of ovarian neoplasms. Management options were also noted.Methods: It is a retrospective study carried out at Goa Medical College between January 2013 to December 2015. All patients diagnosed and treated for ovarian neoplasm were included in the study. Data was tabulated using Microsoft Excel and descriptive statistical analysis was carried out using SPSS version 23.Results: A total of 3111 patients were admitted in gynecology at Goa Medical College during the specified time period. Of these 358 cases were diagnosed with ovarian neoplasm. On histopathology 196 wer...
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Management of Term Prelabour Rupture of Membranes (PROM) remains a matter of debate de... more BACKGROUND Management of Term Prelabour Rupture of Membranes (PROM) remains a matter of debate despite exhaustive research. Aims and Objectives-The objective of this study was to compare use of Tab. Misoprostol per vaginum versus Oxytocin infusion in PROM at term with respect to induction-delivery interval and maternal and foetal outcome. MATERIALS AND METHODS The present study was descriptive comparative study of Tab. Misoprostol (Group A) and Oxytocin infusion (Group B) for induction of labour in PROM at term. The study population consisted of 140 patients. RESULTS Mean induction delivery interval in present study was 541.06 ± 186 minutes in Group A and 556.69 + 219.54 minutes in Group B (p= 0.418), showing no significant difference between two groups. 8.6% women in Group A and 2.9% in Group B had hyperstimulation with no significant difference between the two. There was no significant difference in neonatal complications in the two groups. CONCLUSION The incidences of maternal and foetal untoward effects are similar with use of the two inducing agents with no significant difference in induction delivery interval. Vaginal administration of Misoprostol in a dose of 25 µg 6 hourly to maximum of four doses is an effective alternative of oxytocin for labour induction in term PROM, especially in low resource setups where storage facility for oxytocin and skilled staff for its titration is not available.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in ... more Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research.Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors.Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first ...
A Case of Abdominal Scar Endometriosis a Rare Entity and Review of Literature, Oct 8, 2013
Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common... more Ovarian malignant tumors have varied clinical and biologic behaviour. It is the sixth most common cancer among women (Age standaradised incidence rate being 6.6/100,000) and seventh leading cause of cancer deaths globally (age standaradised mortality rate being 4.0/100,00). 1 In India, during the period 2004-2005, proportion of ovarian cancer varied from 1.7% to 8.7% of all female cancers in various population based registries of Indian Council of Medical Research. The proportion of this cancer was 6.0%-7.7% of all cancers among females in Gujarat. The Age Specific Incidence Rate (ASIR) for ovarian cancer revealed that the disease increases from 35 years of age and reaches a peak between the ages 55-64. 2 Late presentation and ineffective screening methods are impediments in its early detection. The screening tests in form of estimation of CA-125 and Transvaginal sonography are non-specific. 3 Therefore, the diagnosis is made in late stage when cure rates are low and with increased morbidity due to limited effective treatment options. Five-year survival rates range from 30-50% for all ABSTRACT Background: Ovarian malignancy is seventh most common cancer in women globally. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. We present preliminary epidemiological findings to help prioritize research. Methods: Present epidemiological study is retrospective, descriptive study over two years. The collected data was analyzed using SPSS software for overall survival, with respect to stage of disease and histopathology type. Multivariate analysis was done to know independent risk factors. Results: 114 cases of primary ovarian epithelial cancer were analyzed. Patients' mean age at diagnosis was 52.1±8.96 years (median=52). 52.6% patients had stage III disease at first visit. Serous adenocarcinoma (85.05%) was the most prevalent type of histopathology followed by mucinous (7.1%), clear cell (6.1%) and Endometroid carcinoma (1.75%). Surgery followed by combination of taxane and platinum chemotherapy was first line treatment in 35%. The mean age at diagnosis was more with advancing stage (stage one 44±9.53 and stage four 55.35±9.74 years) but it was not statistically significant (p=0.098) Advancing age demonstrated poor survival (log-rank p=0.05) but survival was not significantly different in relation to histopathology (log-rank =0.629). On multivariate regression analysis age of patient (p=0.004), and stage of disease (p=0.005) were found to be independent risk factors while histopathology was not an independent risk factor (p=0.688) for survival. Conclusions: Research should be aimed to find tools for screening and early diagnosis as well as better therapeutic approaches for advanced epithelial ovarian cancer.