Carlos Augusto Fernandes Oliveira | Universidade de São Paulo (original) (raw)

Papers by Carlos Augusto Fernandes Oliveira

The Journal of Poultry Science, 2007

In the present study, the individual and combined e#ects of aflatoxin B+ (AFB+) and fumonisin B+ ... more In the present study, the individual and combined e#ects of aflatoxin B+ (AFB+) and fumonisin B+ (FB+) on the quality of quail eggs were investigated. To this end, ,22 2-week-old Japanese quail were randomly distributed into six experimental groups (.2 birds per group) and fed the following diets for +.* days (five ,2-day laying periods) : +) * (control) ; ,) +* mg FB+/kg ;-) /* mg AFB+/kg ; .) /* mg AFB+/kgῌ+* mg FB+/ kg ; /) ,** mg AFB+/kg ; and 0) ,** mg AFB+/kgῌ+* mg FB+/kg feed. Each treatment consisted of four replicates of twelve quail. Eggs laid in the last day of each ,2-d laying period were collected and submitted for individual analysis for specific gravity, Haugh units and percentage shell. Results showed that by the end of the. th cycle, average egg weight was lower (P῍*.*/) in groups fed /* or ,** mg AFB+/kgῌ+* mg FB+/kg combination diets. Specific gravity decreased (P῍*.*/) in the group fed ,** mg AFB+/kgῌ+* mg FB+/kg by the / th cycle. Feed intake and Haugh units were not a#ected (P῎ *.*/) by AFB+ and/or FB+. Only birds receiving the ,** mg AFB+/kgῌ+* mg FB+/kg diet had decreased (P῍*.*/) percent eggshell by the. th cycle. Data indicated that AFB+ and FB+ in combination have primarily additive e#ects on quail egg weight, specific gravity and percent eggshell at the concentrations used.

In this paper we present a simulator allowing to perform policy experiments relative to the air t... more In this paper we present a simulator allowing to perform policy experiments relative to the air traffic management. Different SESAR solutions can be implemented in the model to see the reaction of the different stakeholders as well as other relevant metrics (delays, safety, etc). The model describes both the strategic phase associated to the planning of the flight trajectories and the tactical modifications occurring in the en-route phase. An implementation of the model is available as open-source and freely accessible by any user. More specifically, different procedures related to business trajectories and free-routing are tested and we illustrate the capabilities of the model on airspace implementing these concepts. After performing numerical simulations with the model, we show that in a free-routing scenario the controllers perform less operations although they are dispersed over a larger portion of the airspace. This can potentially increase the complexity of conflict detection and resolution for controllers. In order to investigate this specific aspect, we consider some metrics used to measure traffic complexity. We first show that in non-free-routing situations our simulator deals with complexity in a way similar to what humans would do. This allows us to be confident that the results of our numerical simulations relative to the free-routing can reasonably forecast how human controllers would behave in this new situation. Specifically, our numerical simulations show that most of the complexity metrics decrease with free-routing, while the few metrics which increase are all linked to the flight level changes. This is a non-trivial result since intuitively the complexity should increase with free-routing because of problematic geometries and more dispersed conflicts over the airspace.

Revista Brasileira de …

DOAJ Directory of Open Access Journals, SPARC Europe Award 2009 English. Free, full text, quality... more DOAJ Directory of Open Access Journals, SPARC Europe Award 2009 English. Free, full text, quality controlled scientific and scholarly journals, covering all subjects and many languages. ...

Arquivos do Instituto …, 2004

... the mammary gland (RANDOLPH &amp; ERWIN, 1974; SCHULTZ, 1977). However, some studies ... more ... the mammary gland (RANDOLPH &amp; ERWIN, 1974; SCHULTZ, 1977). However, some studies have indicated that, similar to SCC effects on total protein content in milk, correlation between SCC and fat percentage may be negative, positive or null (SCHULTZ, 1977; MUNRO et al ...

Food Additives and Contaminants: Part B, 2008

The occurrence of aflatoxins (AF) B1, B2, G1, G2 and cyclopiazonic acid (CPA) in feeds, and AFM1 ... more The occurrence of aflatoxins (AF) B1, B2, G1, G2 and cyclopiazonic acid (CPA) in feeds, and AFM1 and CPA in milk was determined in dairy farms located in the northeastern region of São Paulo state, Brazil, between October 2005 and February 2006. AF and CPA determinations were performed by HPLC. AFB1 was found in 42% of feed at levels of 1.0-26.4 µg kg(-1) (mean: 7.1 ± 7.2 µg kg(-1)). The concentrations of AFM1 in raw milk varied between 0.010 and 0.645 µg l(-1) (mean: 0.104 ± 0.138 µg l(-1)). Only one sample was above the tolerance limit adopted in Brazil (0.50 µg l(-1)) for AFM1 in milk. Regarding CPA in feed, six (12%) samples showed concentrations of 12.5-153.3 µg kg(-1) (mean: 57.6 ± 48.7 µg kg(-1)). CPA was detected in only three milk samples (6%) at levels of 6.4, 8.8 and 9.1 µg l(-1). Concentrations of aflatoxins and CPA in feed and milk were relatively low, although the high frequency of both mycotoxins indicates the necessity to continuously monitor dairy farms to prevent contamination of feed ingredients.

Ciência e Tecnologia de Alimentos, 2010

As aflatoxinas, metabólitos secundários produzidos por certos fungos do gênero Aspergillus, podem... more As aflatoxinas, metabólitos secundários produzidos por certos fungos do gênero Aspergillus, podem causar vários efeitos tóxicos em animais (COUNCIL FOR AGRICULTURE SCIENCE AND TECHNOLOGY, 2003). A exposição humana e de animais às aflatoxinas ocorre predominantemente pela ingestão de alimentos e rações contaminados, especialmente cereais e grãos, como milho, trigo, amendoim, entre outros. Dezoito diferentes tipos de aflatoxinas foram identificados, mas somente as aflatoxinas B 1 (AFB 1), B 2 (AFB 2), G 1 (AFG 1) e G 2 (AFG 2) foram detectadas como contaminantes naturais de rações e ingredientes, sendo a AFB 1 a toxina de maior toxicidade (MOSS, 1998). A contínua ingestão de AFB 1 por animais em lactação leva à excreção de aflatoxina M 1 (AFM 1) no leite (PARK; POHLAND, 1986). Os efeitos tóxicos carcinogênicos da AFM 1 têm sido extensivamente demonstrados em espécies de laboratório (RILEY; PESTKA, 2005), portanto, a International Agency for Research on Cancer (1993) classificou a AFM 1 no Grupo 2 (um provável carcinógeno humano). A taxa de transferência de AFB 1 da ração para o leite de vacas está situada entre 1 e 3%, com uma transferência média de 1,7%, embora estes valores possam variar de acordo com vários fatores como o nível de AFB 1 ingerido, produção de leite, saúde individual e sensibilidade às aflatoxinas (JOUANY; DIAZ, 2005). Frobish et al. (1986) observaram AFM 1 no leite de vacas lactantes, 12 horas após o consumo de ração contaminada, com uma transferência média de 1,74% do total de AFB 1 ingerida na ração. Patterson, Glancy e Roberts (1980) e Price et al. (1985) encontraram resultados semelhantes em vacas leiteiras, observando taxas de transferência de 2,2 e 1,6%, respectivamente. No Brasil, a ocorrência de AFM 1 em leites pasteurizados e esterilizados (longa-vida) é variável (

Applied Radiation and …, 2010

The aim of this study was to evaluate productivity parameters and carcass yield of broiler chicke... more The aim of this study was to evaluate productivity parameters and carcass yield of broiler chickens fed irradiated corn contaminated with mycotoxins. For this purpose, 180 one-day-old male chicks were divided into nine treatments and fed for 42 days. The results indicated that irradiation of corn with 5 kGy improved the productivity parameters studied. Therefore, gamma radiation may become an alternative for the control of the deleterious effects of mycotoxins on broiler chickens, which cause marked economic losses for rural producers.

Italian Journal of Food Science

Aflatoxin M1 (AFM1) is a toxic secreted into the milk of animals fed with diets contaminated by a... more Aflatoxin M1 (AFM1) is a toxic secreted into the milk of animals fed with diets contaminated by aflatoxin B1, which can cause some adverse health effects in humans. The occurrence of AFM1 in dairy products varies based on several factors, including the fermentation process. In this article, the published citations from January 2000 to October 2020 regarding the AFM1 occurrence in industrial and traditional fermented milk were systemically reviewed. According to the findings, a reducing trend in the AFM1 contamination of fermented milk was observed over the years, mainly in traditional products. Despite this trend, further control measures besides the preventative approaches are needed to deal with the high levels of AFM1 in fermented milk.

The individual and combined effects of dietary aflatoxin B 1 (AFB 1) and fumonisin B 1 (FB 1) on ... more The individual and combined effects of dietary aflatoxin B 1 (AFB 1) and fumonisin B 1 (FB 1) on liver pathology, serum levels of aspartate amino-transferase (AST) and plasma total protein (TP) of broilers were evaluated from 8 to 41 days of age. Dietary treatments included a 3 × 3 factorial arrangement with three levels of AFB 1 (0, 50 and 200 μg AFB 1 /kg), and three levels of FB 1 (0, 50 and 200 mg FB 1 /kg). At 33 days post feeding, with the exception of birds fed 50 mg FB 1 only, concentrations of AST were higher (p < 0.05) in all other treatment groups when compared with controls. Plasma TP was lower (p < 0.05) at six days post feeding in groups fed 200 μg AFB 1 /kg alone or in combination with FB 1. At day 33 days post feeding, with the exception of birds fed the highest combination of AFB 1 and FB 1 which had higher plasma TP than control birds , plasma TP of birds fed other dietary treatments were similar to controls. Broilers receiving the highest levels of AFB 1 and FB 1 had bile duct proliferation and trabecular disorder in

Food Science and Technology

Current Research in Nutrition and Food Science Journal

Listeria monocytogenes is a foodborne pathogen which occurs mainly in ready-to-eat food products,... more Listeria monocytogenes is a foodborne pathogen which occurs mainly in ready-to-eat food products, especially in artisanal products manufactured from raw milk such as some types of cheese, meat products and leafy vegetables. L. monocytogenes requires special attention in the food industry because of its ability to survive under adverse conditions and form biofilms on different surfaces in food processing environments. The potential for product contamination by L. monocytogenes strains in the industrial environment emphasizes the importance of preventive measures in the food industry. This review presents an overview on the main characteristics, pathogenicity and occurrence data of L. monocytogenes in Brazilian foods. The main prevention measures to avoid contamination by L. monocytogenes in foods are also highlighted, especially the adoption of quality assurance programs by the food industry.

Trends in Food Science & Technology

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Toxicology reports, 2018

In this study, hepatic biopsies from autopsy cases in São Paulo, Brazil, showing hepatocellular c... more In this study, hepatic biopsies from autopsy cases in São Paulo, Brazil, showing hepatocellular carcinoma (HCC, = 8), cirrhosis associated with viral hepatitis (VC, = 20), cirrhosis associated with alcoholism (AC, = 20), and normal livers (NL or controls, = 10) were subjected to determination of aflatoxin B (AFB) and its main metabolites, and of markers of hepatic carcinogenesis Only non-metabolized AFB was detected in 13 samples (27.1%, = 48) of liver disorders (HCC, VC and AC), at levels between 10.0 and 418.0 pg/g (mean: 76.6 ± 107.7 pg/g). Immuno-labeling of p53, cyclin D1, p21, β-catenin, and Prohibitin (PB) increased mainly in HCC patients, in relation to the controls. AFB+ samples of HCC presented higher expressions of p53, cyclin D1, p21, and β-catenin compared with AFB-livers. In contrast, p27, p16, and Rb immuno-labeling decreased in HCC, VC, and AC samples, compared with NL, with lowest values in AFB+ samples for all liver disorders. Compared with NL, gene expression...