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Brain Injury
The purpose of this study was to determine the clinical correlates of supratentorial ventricular ... more The purpose of this study was to determine the clinical correlates of supratentorial ventricular dilations and of corpus callosal atrophy at the subacute stage after a severe closed-head injury (CHI). Thirty-three CHI patients underwent MRI 2 months or more after injury. Morphometric measures were compared to clinical data (coma score, coma duration and Glasgow Outcome Scale). There were numerous significant correlations between clinical data and mid-third ventricle and frontal horns measurements. Fewer significant correlations were found with the lateral ventricle bodies and the corpus callosal body. There was no significant correlation with the posterior part of the corpus callosum and of the ventricles. Corpus callosum atrophy correlated significantly with anterior and deep ventricular dilatation. In conclusion, the best indicator of clinical status was ventriculomegaly, and particularly third ventricle enlargement, which probably reflects the extent of both anterior and deep white matter lesions.
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Annales de Réadaptation et de Médecine Physique
Mediclen is an occupational health service in charge of following-up 36,736 workers (divided amon... more Mediclen is an occupational health service in charge of following-up 36,736 workers (divided among 1770 companies) in 3 cities of an area near Paris. The employment rate of disabled people among the French population is not well known (rough estimate 4.4%), and few studies have reported on the situation of workers with a motor impairment. The recent computerization of medical records allowed us to identify 195 workers considered disabled by the French administration (i.e. 0.55% of the 36,736 workers followed up in 2002). Among these, 26 had a motor impairment. Twenty-one neurological disabilities were central and 5 were peripheral or neuromuscular. The workers were 44-years-old. Only two workers had a severe handicap. Companies had to adapt workstations for half of the workers, with the advice of neurologists (7 of 10 advice given) and once a physical medicine doctor. The integration of people with motor impairments into the world of work is rare and difficult. This practical experience showed the difficulties people with motor impairment face. Close collaboration of physical medicine services with occupational health services is necessary to improve the integration of this population into the world of work.
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Annales de Réadaptation et de Médecine Physique, 1999
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Annales de Réadaptation et de Médecine Physique, 1997
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Journal of Head Trauma Rehabilitation, 2015
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Annales de Réadaptation et de Médecine Physique, 1997
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Revue Neurologique, 2012
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Annales de Réadaptation et de Médecine Physique, 2003
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Annales de Réadaptation et de Médecine Physique, 1995
... Awareness of deficits was assessed by questioning the patient about his difficulties on the t... more ... Awareness of deficits was assessed by questioning the patient about his difficulties on the ten items of the CBS. ... P Zoccolotti and A Judica, Functional evaluation of hemineglect by means of a semistructured scale: Personal extra-personal differentiation, Neuropsychol Rehabil 1 ...
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Neuropsychologia, Jan 17, 2015
We investigated for the first time the episodic/semantic distinction in remembering the past and ... more We investigated for the first time the episodic/semantic distinction in remembering the past and imagining the future in traumatic brain injury (TBI), and explored cognitive mechanisms that may underlie their deficits. Fifteen severe TBI patients and 15 control participants performed a battery of neuropsychological tests and a set of verbal fluency tasks designed to assess semantic (personality traits knowledge and general events), and episodic (specific events and details) facets of self-representations according to three time periods (remote/retrograde past, recent/anterograde past, future). Compared to controls, TBI patients showed deficits in both semantic and episodic self-representations, regardless of the time period, and controlling for basic cognitive functions. By contrast, a subjective evaluation of self-concept measuring the degree of certitude and the valence of self did not differ between patients and controls. The deficits were mainly predicted by altered executive fu...
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Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique, 2006
Fatigue is frequent and disabling in patients with traumatic brain injury (TBI). Its mechanisms a... more Fatigue is frequent and disabling in patients with traumatic brain injury (TBI). Its mechanisms are complex and multifactorial. We performed a literature review of reports of the condition using the following key words: brain injury, depression, neuroendocrine dysfunction, and treatment. Five scales have been used to evaluate fatigue in TBI patients: the Fatigue Severity Scale, the visual analog scale (VAS) for fatigue, the Fatigue Impact Scale, the Barrow Neurological Institute (BNI) Fatigue Scale and the Cause of Fatigue (COF) Questionnaire. The BNI Fatigue Scale and the COF Questionnaire have been designed specifically for brain-injured patients. Fatigue is present in 43-73% of patients and is one of the first symptoms for 7% of them. Fatigue does not seem to be significantly related to injury severity not to time since injury. It can be related to mental effort necessary to overcome attention deficit and slowed processing ("coping hypothesis"). It can also be related t...
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Neuro-Chirurgie, 2001
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Journal of the International Neuropsychological Society : JINS, 2001
Severe diffuse traumatic brain injury (TBI) may impair the performance of daily-life complex acti... more Severe diffuse traumatic brain injury (TBI) may impair the performance of daily-life complex activities. The aim of the present study was to assess whether these difficulties are related to a representational impairment of action knowledge. Two tasks requiring the manipulation of scripts were used. The first (script reconstitution) required subjects to sort cards describing actions belonging to 4 different scripts, presented in a random order. The second (script generation) required subjects to generate actions belonging to a given script. The results showed that TBI patients had preserved access to goal representation and action knowledge. However, they demonstrated (1) significant impairments when they had to deal with simultaneous competing sources of information and (2) a lack of inhibitory control on routine overlearned skills. Patients' performance was significantly correlated with behavioral modifications in everyday life. These data suggest that action impairment in seve...
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Annals of Physical and Rehabilitation Medicine, 2014
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Annals of Physical and Rehabilitation Medicine, 2014
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Annals of Physical and Rehabilitation Medicine, 2014
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Brain Injury
The purpose of this study was to determine the clinical correlates of supratentorial ventricular ... more The purpose of this study was to determine the clinical correlates of supratentorial ventricular dilations and of corpus callosal atrophy at the subacute stage after a severe closed-head injury (CHI). Thirty-three CHI patients underwent MRI 2 months or more after injury. Morphometric measures were compared to clinical data (coma score, coma duration and Glasgow Outcome Scale). There were numerous significant correlations between clinical data and mid-third ventricle and frontal horns measurements. Fewer significant correlations were found with the lateral ventricle bodies and the corpus callosal body. There was no significant correlation with the posterior part of the corpus callosum and of the ventricles. Corpus callosum atrophy correlated significantly with anterior and deep ventricular dilatation. In conclusion, the best indicator of clinical status was ventriculomegaly, and particularly third ventricle enlargement, which probably reflects the extent of both anterior and deep white matter lesions.
Bookmarks Related papers MentionsView impact
Annales de Réadaptation et de Médecine Physique
Mediclen is an occupational health service in charge of following-up 36,736 workers (divided amon... more Mediclen is an occupational health service in charge of following-up 36,736 workers (divided among 1770 companies) in 3 cities of an area near Paris. The employment rate of disabled people among the French population is not well known (rough estimate 4.4%), and few studies have reported on the situation of workers with a motor impairment. The recent computerization of medical records allowed us to identify 195 workers considered disabled by the French administration (i.e. 0.55% of the 36,736 workers followed up in 2002). Among these, 26 had a motor impairment. Twenty-one neurological disabilities were central and 5 were peripheral or neuromuscular. The workers were 44-years-old. Only two workers had a severe handicap. Companies had to adapt workstations for half of the workers, with the advice of neurologists (7 of 10 advice given) and once a physical medicine doctor. The integration of people with motor impairments into the world of work is rare and difficult. This practical experience showed the difficulties people with motor impairment face. Close collaboration of physical medicine services with occupational health services is necessary to improve the integration of this population into the world of work.
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Bookmarks Related papers MentionsView impact
Annales de Réadaptation et de Médecine Physique, 1999
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Annales de Réadaptation et de Médecine Physique, 1997
Bookmarks Related papers MentionsView impact
Bookmarks Related papers MentionsView impact
Journal of Head Trauma Rehabilitation, 2015
Bookmarks Related papers MentionsView impact
Annales de Réadaptation et de Médecine Physique, 1997
Bookmarks Related papers MentionsView impact
Revue Neurologique, 2012
Bookmarks Related papers MentionsView impact
Annales de Réadaptation et de Médecine Physique, 2003
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Annales de Réadaptation et de Médecine Physique, 1995
... Awareness of deficits was assessed by questioning the patient about his difficulties on the t... more ... Awareness of deficits was assessed by questioning the patient about his difficulties on the ten items of the CBS. ... P Zoccolotti and A Judica, Functional evaluation of hemineglect by means of a semistructured scale: Personal extra-personal differentiation, Neuropsychol Rehabil 1 ...
Bookmarks Related papers MentionsView impact
Neuropsychologia, Jan 17, 2015
We investigated for the first time the episodic/semantic distinction in remembering the past and ... more We investigated for the first time the episodic/semantic distinction in remembering the past and imagining the future in traumatic brain injury (TBI), and explored cognitive mechanisms that may underlie their deficits. Fifteen severe TBI patients and 15 control participants performed a battery of neuropsychological tests and a set of verbal fluency tasks designed to assess semantic (personality traits knowledge and general events), and episodic (specific events and details) facets of self-representations according to three time periods (remote/retrograde past, recent/anterograde past, future). Compared to controls, TBI patients showed deficits in both semantic and episodic self-representations, regardless of the time period, and controlling for basic cognitive functions. By contrast, a subjective evaluation of self-concept measuring the degree of certitude and the valence of self did not differ between patients and controls. The deficits were mainly predicted by altered executive fu...
Bookmarks Related papers MentionsView impact
Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique, 2006
Fatigue is frequent and disabling in patients with traumatic brain injury (TBI). Its mechanisms a... more Fatigue is frequent and disabling in patients with traumatic brain injury (TBI). Its mechanisms are complex and multifactorial. We performed a literature review of reports of the condition using the following key words: brain injury, depression, neuroendocrine dysfunction, and treatment. Five scales have been used to evaluate fatigue in TBI patients: the Fatigue Severity Scale, the visual analog scale (VAS) for fatigue, the Fatigue Impact Scale, the Barrow Neurological Institute (BNI) Fatigue Scale and the Cause of Fatigue (COF) Questionnaire. The BNI Fatigue Scale and the COF Questionnaire have been designed specifically for brain-injured patients. Fatigue is present in 43-73% of patients and is one of the first symptoms for 7% of them. Fatigue does not seem to be significantly related to injury severity not to time since injury. It can be related to mental effort necessary to overcome attention deficit and slowed processing ("coping hypothesis"). It can also be related t...
Bookmarks Related papers MentionsView impact
Neuro-Chirurgie, 2001
Bookmarks Related papers MentionsView impact
Journal of the International Neuropsychological Society : JINS, 2001
Severe diffuse traumatic brain injury (TBI) may impair the performance of daily-life complex acti... more Severe diffuse traumatic brain injury (TBI) may impair the performance of daily-life complex activities. The aim of the present study was to assess whether these difficulties are related to a representational impairment of action knowledge. Two tasks requiring the manipulation of scripts were used. The first (script reconstitution) required subjects to sort cards describing actions belonging to 4 different scripts, presented in a random order. The second (script generation) required subjects to generate actions belonging to a given script. The results showed that TBI patients had preserved access to goal representation and action knowledge. However, they demonstrated (1) significant impairments when they had to deal with simultaneous competing sources of information and (2) a lack of inhibitory control on routine overlearned skills. Patients' performance was significantly correlated with behavioral modifications in everyday life. These data suggest that action impairment in seve...
Bookmarks Related papers MentionsView impact
Annals of Physical and Rehabilitation Medicine, 2014
Bookmarks Related papers MentionsView impact
Annals of Physical and Rehabilitation Medicine, 2014
Bookmarks Related papers MentionsView impact
Annals of Physical and Rehabilitation Medicine, 2014
Bookmarks Related papers MentionsView impact