Geeta Kurhade | University of the West Indies, St. Augustine (original) (raw)
Papers by Geeta Kurhade
Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous ... more Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous membrane many times culminating in respiratory distress and COPD. This causes increased morbidity and loss of work hours for the affected individuals. Objective: To estimate the prevalence of respiratory symptoms and lung functions in individuals exposed to mixed bio aerosols in a vegetable market and to test the association of age of an individual with various lung function tests. Materials and Methods: Bio aerosol characteristics of air in the market were analysed by Reusable Aluminium Two Stage Viable Anderson Cascade Impactor. Spirometry with American Thoracic Society (ATS) standards was done in non-smoker 640 individuals; 210 individuals exposed to dust and 430 individuals living around the same area but not exposed to dust. According to age 2 groups were made. Group A (20-30years) having 110 exposed and 220 unexposed individuals .Group B (31-40years) having 100 exposed and 210 unex...
Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and ... more Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and the profile of the fungi responsible in this region. Special attention was given to assess the prevalence of various species of Aspergillus, predisposing factors for keratomycosis and drug sensitivity. Methods: Corneal scraping samples from 148 cases of corneal ulcer and traumatic corneal infection with clinically suspicion of having fungal infections were examined microscopically and for culture. Minimum inhibitory concentration (MIC) of itraconazole and amphotericin-B were tested against the Aspergillus species isolates. Results: Aspergillus species were isolated in 26 (20.15%) cases and Aspergillus fumigatus was the predominant species isolated in 17 (65.38%) cases. This fungus was found to be sensitive to itraconazole with MIC of 0,125 -1 µg/ml. Conclusion: Aspergillus fumigatus is more common in mycotic keratitis, and itraconazole is effective against it. Vegetative trauma is the ma...
American Journal of Infectious Diseases and Microbiology, 2016
Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and ... more Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and the profile of the fungi responsible in this region. Special attention was given to assess the prevalence of various species of Aspergillus, predisposing factors for keratomycosis and drug sensitivity. Methods: Corneal scraping samples from 148 cases of corneal ulcer and traumatic corneal infection with clinically suspicion of having fungal infections were examined microscopically and for culture. Minimum inhibitory concentration (MIC) of itraconazole and amphotericin-B were tested against the Aspergillus species isolates. Results: Aspergillus species were isolated in 26 (20.15%) cases and Aspergillus fumigatus was the predominant species isolated in 17 (65.38%) cases. This fungus was found to be sensitive to itraconazole with MIC of 0,125 -1 µg/ml. Conclusion: Aspergillus fumigatus is more common in mycotic keratitis, and itraconazole is effective against it. Vegetative trauma is the ma...
The aim of this research was to carry out a bacteriological study of Vibrio cholerae in Central I... more The aim of this research was to carry out a bacteriological study of Vibrio cholerae in Central India. Cholera is an important public health problem in India and it continues to be a major concern as it is an important cause of morbidity mortality. A total of 44 strains of V. cholerae were isolated from 150 stool samples received from patients with acute diarrhea. All samples were plated onto different bacteriological media. Biotyping was performed as per the standard procedures. Confirmation of the strains was done by seroagglutination using Polyvalent O1, monospecific Ogawa and Inaba antisera. Antibiotic susceptibility testing was performed by Kirby Bauer's disk diffusion method. The majority of the isolates belonged to type 27 (70.45%, i.e. 31 isolates). All Isolates were susceptible to tetracycline, norfloxacin and were relatively susceptible to gentamicin (95%) and chloramphenicol (95%). Continued monitoring, surveillance of all outbreaks and notification to relevant author...
Journal of Veterinary Science & Technology, 2015
Objective: To purify IgG molecules from several species by SpA-affinity chromatography and to stu... more Objective: To purify IgG molecules from several species by SpA-affinity chromatography and to study the interactions of mammalian IgGs with a peroxidase-labelled SpL, SpA and SpG conjugate (SPLAG-HRP) in an enzyme-linked immunosorbent assay (ELISA). Materials and methods: The periodate method described by Nakane and Kawoi was used to prepare the SPLAG-HRP conjugate. The 10% non-denaturing sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) of sera and purified immunoglobulins was carried out to characterize molecularly the purified IgGs. The chicken IgY fraction was isolated by the chloroform-polyethylene glycol (PEG) method for its use as a negative control in the ELISA that was used to determine the affinity of different immunoglobulins to a SPLAG-HRP conjugate. Results: The SpA-affinity chromatography and the 10% non-denaturing SDS-PAGE of sera and purified immunoglobulins (IgGs) were useful separation techniques. Most purified IgGs interacted moderately with the SPLAG-HRP including IgGs from horse, dog, skunk, coyote and raccoon. The purified mammalian IgG had a molecular weight (MW) of approximately 150 kDa. Conclusion: The SPLAG-HRP was a versatile heterofunctional reagent useful for the detection of purified immunoglobulins from diverse mammalian species.
Journal of Bacteriology & Parasitology, 2015
Journal of Chromatography & Separation Techniques, 2013
Journal of Vaccines & Vaccination, 2013
The aim of this preliminary study was to produce anti HIV antibodies against the fragment 579 601... more The aim of this preliminary study was to produce anti HIV antibodies against the fragment 579 601 of the HIV gp41 and fragments 308 331 and 421 438 of the HIV gp120 from the human immunodeficiency virus (HIV) in layer hens. Keyhole limpet hemocynin (KLH) was conjugated to HIV synthetic peptides by the glutaraldehyde method after they were dimerized by cysteine oxidation with dimethyl sulfide. Two healthy brown Leghorn layer hens (per immunogen) were injected intramuscularly on the breasts with KLH peptide conjugated vaccines. They were immunized on days 0,21,45 and 60. Enzyme linked immunosorbent assays (ELISA) were used to test for anti HIV antibodies and there was a statistical significance in the mean of optical density readings between pre immunized and post immunized animals, proving the formation of specific antibodies. These molecules can potentially be used as therapeutic agents or diagnostic reagents. The limitations of this investigation were the small number of cases, viral neutralization produced by anti HIV antibodies was not tested in cell cultures neither their capacity to inhibit the HIV entry into the CD4+ lymphocyte. We conclude that KLH peptide conjugated vaccines against regions of the gp120 and gp41 effectively produced a strong immune response in egg yolks from layer hens. Despite of limitations of this investigation we report an outcome that encourages us to design and perform a larger study, which can be done in future.
Journal of Chromatography & Separation Techniques, 2013
Archives of Microbiology & Immunology, 2017
The aim of this study was to assess sero-prevelance of Parvovirus B19 among HIV positive patients... more The aim of this study was to assess sero-prevelance of Parvovirus B19 among HIV positive patients attending tertiary care hospital from central India. Methods: This was a hospital based cross sectional study conducted from June 2014 to September 2014. The study population includes 100 HIV positive patients attending ART Clinic with signs and symptoms suggestive of anemia and hemoglobin <10g/dL were included. Blood samples were collected and the sera obtained after centrifugation of clotted samples were stored at-20ºC. Enzyme-linked immunesorbent assay was used to detect IgG and IgM antibodies. CD4 + count estimation of blood samples was done by Flow cytometry. The demographic information's were collected from patients using structured questionnaire prior to sample collection. Institutional Ethical committee approval has been taken prior to conduct this study. The consent to collect the study data was also obtained from the patients. The data were analyzed using statistical software Epi Info 7. Results: The mean age of study subjects was 37.44±9.80 years and 55 (55%) were males and 45 (45%) were females. IgG and IgM antibody test showed, 6 (6%) and 11 (11%) cases were positive for anti-parvovirus IgM and
Microbiology Research Journal International
Background: Toxoplasma gondii an intracellular protozoan causes toxoplasmosis a worldwide neglect... more Background: Toxoplasma gondii an intracellular protozoan causes toxoplasmosis a worldwide neglected tropical disease, which also causes severe disease in immunocompromised patients. The Toxoplasmosis was known for cerebral involvement more commonly among patients with HIV/AIDS and serious than extra-cerebral toxoplasmosis. For cerebral toxoplasmosis patients the definitive diagnosis is crucial by demonstrating the presence of the tachyzoite form of Toxoplasma gondii directly in the cerebral tissues. This study was undertaken to assess the prevalence of toxoplasmosis among HIV patients and role of radiological investigation in the diagnosis. Materials and Methods: A prospective cross-sectional study was conducted at Department of
The Journal of sports medicine and physical fitness, Jan 29, 2017
Persistent bouts of extended exercise and heavy training are associated with depressed immune cel... more Persistent bouts of extended exercise and heavy training are associated with depressed immune cell function. It has recently been demonstrated that IL-6 is produced locally in contracting skeletal muscles and acts on a wide range of tissues. Larger amounts of IL-6 are produced in response to exercise than any other cytokines. Though the majority of existing data obtained following prolonged exercise, it remains to be explained the effect of martial arts training on IL-6 and other immunological parameters and associated changes to the duration of this type of exercise. IL-1α is produced mainly by activated macrophages, as well as neutrophils epithelial cells, and endothelial cells. It possesses metabolic, physiological, hematopoietic activities, and plays one of the central roles in the regulation of the immune responses. This study aimed to evaluate the effect of martial arts training on IL-6 and other immunological parameters among Trinidadian subjects. Sixteen healthy, nonsmoker i...
International Journal of Health and Rehabilitation Sciences, 2013
Journal of Analytical & Bioanalytical Techniques, 2013
ABSTRACT T his article was originally published in a journal by OMICS Publishing Group, and the a... more ABSTRACT T his article was originally published in a journal by OMICS Publishing Group, and the attached copy is provided by OMICS Publishing Group for the author's benefit and for the benefit of the author's institution, for commercial/research/educational use including without limitation use in instruction at your institution, sending it to specific colleagues that you know, and providing a copy to your institution's administrator. All other uses, reproduction and distribution, including without limitation commercial reprints, selling or licensing copies or access, or posting on open internet sites, your personal or institution's website or repository, are requested to cite properly.
Integrative Molecular Medicine, 2016
Breast engorgement is, the swelling and distension of breasts, usually in the early days of initi... more Breast engorgement is, the swelling and distension of breasts, usually in the early days of initiation of lactation, due to vascular dilatation as well as the arrival of the milk. Breast engorgement occurs in 72% to 82% of lactating women. Various physiotherapeutic interventions for treatment of breast engorgement have been documented such as, Hot Moist Pack, Massage, Ultrasound. Although Ultrasound is used in the treatment of breast engorgement but literature is scarce on use of it. The objective of the present study was to comparative effectiveness of ultrasound therapy with conventional therapy on breast engorgement in immediate post-partum mothers. In randomized controlled trial, 80 post-partum mothers with breast engorgement were randomly assigned to Group A (Ultrasound therapy) and Group B (Conventional therapy) during the study period from April, 2010 to December 2010. The outcome measures used were Visual Analogue Scale (VAS), Hardness scale and Six-point engorgement scale (SPES). The pre-treatment and post-treatment values of outcome measures were noted on for all the four days. The intra group comparison results showed that pain on VAS, hardness score and SPES score was statistically significant in both groups. Whereas inter-group comparison results showed that VAS was statistically significant on 2 nd and 3 rd day post-intervention. Pre-intervention and post-intervention at 4 th day were statistically significant in both groups by the hardness and SPES scores. The study concluded that ultrasound therapy added with conventional therapy helps in reduction of pain with non-tender breasts which further helps the post-partum mothers to recover better from discomforts of breast engorgement. This in turn can facilitate better breast feeding.
![Research paper thumbnail of Kurhade G, Kurhade A, Phatak MS, Farid Y. A Cross Sectional Study of Respiratory Symptoms and Spirometry in Adults Exposed to Bio aerosol in Vegetable Market in India. Int J Health Rehabil Sci. (2013), [cited February 19, 2013]; 2(1): 15- 21](https://attachments.academia-assets.com/41494814/thumbnails/1.jpg)
](Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous ... more Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous membrane many times culminating in respiratory distress and COPD. This causes increased morbidity and loss of work hours for the affected individuals.
Indian journal of physiology and pharmacology
The study deals with evaluation of pulmonary function status in fifty normal pregnant women teste... more The study deals with evaluation of pulmonary function status in fifty normal pregnant women tested monthly. The parameters studied were Vital Capacity (VC) Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1st second (FEV1) using Vitalograph Spirometer; tidal volume (VT), inspiratory capacity (IC) and expiratory reserve volume (ERV) using Expirograph and resting minute ventilation (VE) using Tissot's spirometer. Control values were obtained in the same subject 8-10 weeks after delivery. The increase seen in VT, VE and IC was very highly significant. The small increment in frequency of respiration is significant and the declining trend observed in ERV is very highly significant. VC and FVC were maintained by the rise in IC and a concomitant fall in ERV. Rise in VC is attributed mainly to rise in VT than rise in frequency. The results suggest that though pulmonary function is altered during pregnancy, it is not compromised and hence does not induce any mechanical stress ...
Indian journal of physiology and pharmacology
This study presents a composite picture of haemoglobin (Hb), serum level of iron (SI), total iron... more This study presents a composite picture of haemoglobin (Hb), serum level of iron (SI), total iron binding capacity (TIBC) and percent iron saturation of transferrin in women during different trimesters of pregnancy and postpartum period. The results were correlated with age and parity. A total of 75 subjects, 15 from each trimester and 15 postpartal, were studied and compared with 15 nonpregnant normal subjects. Signs of increased iron demand, increased iron turnover and obvious iron deficiency, were demonstrated throughout pregnancy, by decrease in haemoglobin, SI, percent iron saturation of transferrin and increased TIBC; especially in older age group and multigravidae. SI, TIBC and percent iron saturation of transferrin are more sensitive indices of iron status and provide us an opportunity to replenish iron stores of an iron deficient pregnant mother at an earlier date thus preventing anaemia.
Indian Journal of Medical Sciences
Indian journal of physiology and pharmacology
1. It has been reported that, during incremental exercise testing, the patterns of change in vent... more 1. It has been reported that, during incremental exercise testing, the patterns of change in ventilation (VE) and arterial K+ (Ka+) are similar, suggesting that changing Ka+ may lead to the phenomenon of the ventilatory threshold through its action on the peripheral chemoreceptors. 2. Expiratory ventilation, oxygen consumption, CO2 production (VE, VO2, VCO2), arterialized venous PCO2 (Pav, CO2; see Methods), pH (pHav), K+ (Kav+) and lactate were measured during incremental exercise tests undertaken by six normal male subjects under control conditions and during lactic acidosis following severe exercise (experimental trial). 3. A ventilatory threshold, associated with a period of isocapnic buffering, was observed under both control and experimental conditions. During the control trial, plots of Kav+ against VO2 showed an inflexion close to the ventilatory threshold. Throughout the experimental trial Kav+ rose linearly relative to VO2. In both control and experimental trials Kav+ concentrations were similar at the ventilatory threshold. 4. These results suggest that the pattern of change of Ka+ cannot account for the phenomenon of the ventilatory threshold. The possibility that the peripheral chemoreceptor response is non-linear above a critical value of Ka+ requires further investigation.
Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous ... more Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous membrane many times culminating in respiratory distress and COPD. This causes increased morbidity and loss of work hours for the affected individuals. Objective: To estimate the prevalence of respiratory symptoms and lung functions in individuals exposed to mixed bio aerosols in a vegetable market and to test the association of age of an individual with various lung function tests. Materials and Methods: Bio aerosol characteristics of air in the market were analysed by Reusable Aluminium Two Stage Viable Anderson Cascade Impactor. Spirometry with American Thoracic Society (ATS) standards was done in non-smoker 640 individuals; 210 individuals exposed to dust and 430 individuals living around the same area but not exposed to dust. According to age 2 groups were made. Group A (20-30years) having 110 exposed and 220 unexposed individuals .Group B (31-40years) having 100 exposed and 210 unex...
Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and ... more Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and the profile of the fungi responsible in this region. Special attention was given to assess the prevalence of various species of Aspergillus, predisposing factors for keratomycosis and drug sensitivity. Methods: Corneal scraping samples from 148 cases of corneal ulcer and traumatic corneal infection with clinically suspicion of having fungal infections were examined microscopically and for culture. Minimum inhibitory concentration (MIC) of itraconazole and amphotericin-B were tested against the Aspergillus species isolates. Results: Aspergillus species were isolated in 26 (20.15%) cases and Aspergillus fumigatus was the predominant species isolated in 17 (65.38%) cases. This fungus was found to be sensitive to itraconazole with MIC of 0,125 -1 µg/ml. Conclusion: Aspergillus fumigatus is more common in mycotic keratitis, and itraconazole is effective against it. Vegetative trauma is the ma...
American Journal of Infectious Diseases and Microbiology, 2016
Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and ... more Purpose: The present study was undertaken to investigate the prevalence of mycotic keratitis and the profile of the fungi responsible in this region. Special attention was given to assess the prevalence of various species of Aspergillus, predisposing factors for keratomycosis and drug sensitivity. Methods: Corneal scraping samples from 148 cases of corneal ulcer and traumatic corneal infection with clinically suspicion of having fungal infections were examined microscopically and for culture. Minimum inhibitory concentration (MIC) of itraconazole and amphotericin-B were tested against the Aspergillus species isolates. Results: Aspergillus species were isolated in 26 (20.15%) cases and Aspergillus fumigatus was the predominant species isolated in 17 (65.38%) cases. This fungus was found to be sensitive to itraconazole with MIC of 0,125 -1 µg/ml. Conclusion: Aspergillus fumigatus is more common in mycotic keratitis, and itraconazole is effective against it. Vegetative trauma is the ma...
The aim of this research was to carry out a bacteriological study of Vibrio cholerae in Central I... more The aim of this research was to carry out a bacteriological study of Vibrio cholerae in Central India. Cholera is an important public health problem in India and it continues to be a major concern as it is an important cause of morbidity mortality. A total of 44 strains of V. cholerae were isolated from 150 stool samples received from patients with acute diarrhea. All samples were plated onto different bacteriological media. Biotyping was performed as per the standard procedures. Confirmation of the strains was done by seroagglutination using Polyvalent O1, monospecific Ogawa and Inaba antisera. Antibiotic susceptibility testing was performed by Kirby Bauer's disk diffusion method. The majority of the isolates belonged to type 27 (70.45%, i.e. 31 isolates). All Isolates were susceptible to tetracycline, norfloxacin and were relatively susceptible to gentamicin (95%) and chloramphenicol (95%). Continued monitoring, surveillance of all outbreaks and notification to relevant author...
Journal of Veterinary Science & Technology, 2015
Objective: To purify IgG molecules from several species by SpA-affinity chromatography and to stu... more Objective: To purify IgG molecules from several species by SpA-affinity chromatography and to study the interactions of mammalian IgGs with a peroxidase-labelled SpL, SpA and SpG conjugate (SPLAG-HRP) in an enzyme-linked immunosorbent assay (ELISA). Materials and methods: The periodate method described by Nakane and Kawoi was used to prepare the SPLAG-HRP conjugate. The 10% non-denaturing sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) of sera and purified immunoglobulins was carried out to characterize molecularly the purified IgGs. The chicken IgY fraction was isolated by the chloroform-polyethylene glycol (PEG) method for its use as a negative control in the ELISA that was used to determine the affinity of different immunoglobulins to a SPLAG-HRP conjugate. Results: The SpA-affinity chromatography and the 10% non-denaturing SDS-PAGE of sera and purified immunoglobulins (IgGs) were useful separation techniques. Most purified IgGs interacted moderately with the SPLAG-HRP including IgGs from horse, dog, skunk, coyote and raccoon. The purified mammalian IgG had a molecular weight (MW) of approximately 150 kDa. Conclusion: The SPLAG-HRP was a versatile heterofunctional reagent useful for the detection of purified immunoglobulins from diverse mammalian species.
Journal of Bacteriology & Parasitology, 2015
Journal of Chromatography & Separation Techniques, 2013
Journal of Vaccines & Vaccination, 2013
The aim of this preliminary study was to produce anti HIV antibodies against the fragment 579 601... more The aim of this preliminary study was to produce anti HIV antibodies against the fragment 579 601 of the HIV gp41 and fragments 308 331 and 421 438 of the HIV gp120 from the human immunodeficiency virus (HIV) in layer hens. Keyhole limpet hemocynin (KLH) was conjugated to HIV synthetic peptides by the glutaraldehyde method after they were dimerized by cysteine oxidation with dimethyl sulfide. Two healthy brown Leghorn layer hens (per immunogen) were injected intramuscularly on the breasts with KLH peptide conjugated vaccines. They were immunized on days 0,21,45 and 60. Enzyme linked immunosorbent assays (ELISA) were used to test for anti HIV antibodies and there was a statistical significance in the mean of optical density readings between pre immunized and post immunized animals, proving the formation of specific antibodies. These molecules can potentially be used as therapeutic agents or diagnostic reagents. The limitations of this investigation were the small number of cases, viral neutralization produced by anti HIV antibodies was not tested in cell cultures neither their capacity to inhibit the HIV entry into the CD4+ lymphocyte. We conclude that KLH peptide conjugated vaccines against regions of the gp120 and gp41 effectively produced a strong immune response in egg yolks from layer hens. Despite of limitations of this investigation we report an outcome that encourages us to design and perform a larger study, which can be done in future.
Journal of Chromatography & Separation Techniques, 2013
Archives of Microbiology & Immunology, 2017
The aim of this study was to assess sero-prevelance of Parvovirus B19 among HIV positive patients... more The aim of this study was to assess sero-prevelance of Parvovirus B19 among HIV positive patients attending tertiary care hospital from central India. Methods: This was a hospital based cross sectional study conducted from June 2014 to September 2014. The study population includes 100 HIV positive patients attending ART Clinic with signs and symptoms suggestive of anemia and hemoglobin <10g/dL were included. Blood samples were collected and the sera obtained after centrifugation of clotted samples were stored at-20ºC. Enzyme-linked immunesorbent assay was used to detect IgG and IgM antibodies. CD4 + count estimation of blood samples was done by Flow cytometry. The demographic information's were collected from patients using structured questionnaire prior to sample collection. Institutional Ethical committee approval has been taken prior to conduct this study. The consent to collect the study data was also obtained from the patients. The data were analyzed using statistical software Epi Info 7. Results: The mean age of study subjects was 37.44±9.80 years and 55 (55%) were males and 45 (45%) were females. IgG and IgM antibody test showed, 6 (6%) and 11 (11%) cases were positive for anti-parvovirus IgM and
Microbiology Research Journal International
Background: Toxoplasma gondii an intracellular protozoan causes toxoplasmosis a worldwide neglect... more Background: Toxoplasma gondii an intracellular protozoan causes toxoplasmosis a worldwide neglected tropical disease, which also causes severe disease in immunocompromised patients. The Toxoplasmosis was known for cerebral involvement more commonly among patients with HIV/AIDS and serious than extra-cerebral toxoplasmosis. For cerebral toxoplasmosis patients the definitive diagnosis is crucial by demonstrating the presence of the tachyzoite form of Toxoplasma gondii directly in the cerebral tissues. This study was undertaken to assess the prevalence of toxoplasmosis among HIV patients and role of radiological investigation in the diagnosis. Materials and Methods: A prospective cross-sectional study was conducted at Department of
The Journal of sports medicine and physical fitness, Jan 29, 2017
Persistent bouts of extended exercise and heavy training are associated with depressed immune cel... more Persistent bouts of extended exercise and heavy training are associated with depressed immune cell function. It has recently been demonstrated that IL-6 is produced locally in contracting skeletal muscles and acts on a wide range of tissues. Larger amounts of IL-6 are produced in response to exercise than any other cytokines. Though the majority of existing data obtained following prolonged exercise, it remains to be explained the effect of martial arts training on IL-6 and other immunological parameters and associated changes to the duration of this type of exercise. IL-1α is produced mainly by activated macrophages, as well as neutrophils epithelial cells, and endothelial cells. It possesses metabolic, physiological, hematopoietic activities, and plays one of the central roles in the regulation of the immune responses. This study aimed to evaluate the effect of martial arts training on IL-6 and other immunological parameters among Trinidadian subjects. Sixteen healthy, nonsmoker i...
International Journal of Health and Rehabilitation Sciences, 2013
Journal of Analytical & Bioanalytical Techniques, 2013
ABSTRACT T his article was originally published in a journal by OMICS Publishing Group, and the a... more ABSTRACT T his article was originally published in a journal by OMICS Publishing Group, and the attached copy is provided by OMICS Publishing Group for the author's benefit and for the benefit of the author's institution, for commercial/research/educational use including without limitation use in instruction at your institution, sending it to specific colleagues that you know, and providing a copy to your institution's administrator. All other uses, reproduction and distribution, including without limitation commercial reprints, selling or licensing copies or access, or posting on open internet sites, your personal or institution's website or repository, are requested to cite properly.
Integrative Molecular Medicine, 2016
Breast engorgement is, the swelling and distension of breasts, usually in the early days of initi... more Breast engorgement is, the swelling and distension of breasts, usually in the early days of initiation of lactation, due to vascular dilatation as well as the arrival of the milk. Breast engorgement occurs in 72% to 82% of lactating women. Various physiotherapeutic interventions for treatment of breast engorgement have been documented such as, Hot Moist Pack, Massage, Ultrasound. Although Ultrasound is used in the treatment of breast engorgement but literature is scarce on use of it. The objective of the present study was to comparative effectiveness of ultrasound therapy with conventional therapy on breast engorgement in immediate post-partum mothers. In randomized controlled trial, 80 post-partum mothers with breast engorgement were randomly assigned to Group A (Ultrasound therapy) and Group B (Conventional therapy) during the study period from April, 2010 to December 2010. The outcome measures used were Visual Analogue Scale (VAS), Hardness scale and Six-point engorgement scale (SPES). The pre-treatment and post-treatment values of outcome measures were noted on for all the four days. The intra group comparison results showed that pain on VAS, hardness score and SPES score was statistically significant in both groups. Whereas inter-group comparison results showed that VAS was statistically significant on 2 nd and 3 rd day post-intervention. Pre-intervention and post-intervention at 4 th day were statistically significant in both groups by the hardness and SPES scores. The study concluded that ultrasound therapy added with conventional therapy helps in reduction of pain with non-tender breasts which further helps the post-partum mothers to recover better from discomforts of breast engorgement. This in turn can facilitate better breast feeding.
Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous ... more Background: Bio aerosol pollution of workplace environment mainly affects the airways and mucous membrane many times culminating in respiratory distress and COPD. This causes increased morbidity and loss of work hours for the affected individuals.
Indian journal of physiology and pharmacology
The study deals with evaluation of pulmonary function status in fifty normal pregnant women teste... more The study deals with evaluation of pulmonary function status in fifty normal pregnant women tested monthly. The parameters studied were Vital Capacity (VC) Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1st second (FEV1) using Vitalograph Spirometer; tidal volume (VT), inspiratory capacity (IC) and expiratory reserve volume (ERV) using Expirograph and resting minute ventilation (VE) using Tissot's spirometer. Control values were obtained in the same subject 8-10 weeks after delivery. The increase seen in VT, VE and IC was very highly significant. The small increment in frequency of respiration is significant and the declining trend observed in ERV is very highly significant. VC and FVC were maintained by the rise in IC and a concomitant fall in ERV. Rise in VC is attributed mainly to rise in VT than rise in frequency. The results suggest that though pulmonary function is altered during pregnancy, it is not compromised and hence does not induce any mechanical stress ...
Indian journal of physiology and pharmacology
This study presents a composite picture of haemoglobin (Hb), serum level of iron (SI), total iron... more This study presents a composite picture of haemoglobin (Hb), serum level of iron (SI), total iron binding capacity (TIBC) and percent iron saturation of transferrin in women during different trimesters of pregnancy and postpartum period. The results were correlated with age and parity. A total of 75 subjects, 15 from each trimester and 15 postpartal, were studied and compared with 15 nonpregnant normal subjects. Signs of increased iron demand, increased iron turnover and obvious iron deficiency, were demonstrated throughout pregnancy, by decrease in haemoglobin, SI, percent iron saturation of transferrin and increased TIBC; especially in older age group and multigravidae. SI, TIBC and percent iron saturation of transferrin are more sensitive indices of iron status and provide us an opportunity to replenish iron stores of an iron deficient pregnant mother at an earlier date thus preventing anaemia.
Indian Journal of Medical Sciences
Indian journal of physiology and pharmacology
1. It has been reported that, during incremental exercise testing, the patterns of change in vent... more 1. It has been reported that, during incremental exercise testing, the patterns of change in ventilation (VE) and arterial K+ (Ka+) are similar, suggesting that changing Ka+ may lead to the phenomenon of the ventilatory threshold through its action on the peripheral chemoreceptors. 2. Expiratory ventilation, oxygen consumption, CO2 production (VE, VO2, VCO2), arterialized venous PCO2 (Pav, CO2; see Methods), pH (pHav), K+ (Kav+) and lactate were measured during incremental exercise tests undertaken by six normal male subjects under control conditions and during lactic acidosis following severe exercise (experimental trial). 3. A ventilatory threshold, associated with a period of isocapnic buffering, was observed under both control and experimental conditions. During the control trial, plots of Kav+ against VO2 showed an inflexion close to the ventilatory threshold. Throughout the experimental trial Kav+ rose linearly relative to VO2. In both control and experimental trials Kav+ concentrations were similar at the ventilatory threshold. 4. These results suggest that the pattern of change of Ka+ cannot account for the phenomenon of the ventilatory threshold. The possibility that the peripheral chemoreceptor response is non-linear above a critical value of Ka+ requires further investigation.