Characterization of Chrysin Glucuronidation in UGT1A1-Overexpressing HeLa Cells: Elucidating the Transporters Responsible for Efflux of Glucuronide (original ) (raw )Glucuronidation: Driving Factors and Their Impact on Glucuronide Disposition
Rashim Singh
Drug metabolism reviews, 2017
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Characterization of In Vitro Glucuronidation Clearance of a Range of Drugs in Human Kidney Microsomes: Comparison with Liver and Intestinal Glucuronidation and Impact of Albumin
Taoufik Masmoudi
Drug Metabolism and Disposition, 2012
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Evidence for multiple glucuronide transporters in rat liver microsomes
Miklós Csala
Biochemical Pharmacology, 2004
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Glucuronidation of Antiallergic Drug, Tranilast: Identification of Human UDP-Glucuronosyltransferase Isoforms and Effect of Its Phase I Metabolite
Tomoko Matsui
Drug Metabolism and Disposition, 2007
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ATP-Dependent transport for glucuronides in canalicular plasma membrane vesicles
Hisanori Hara
Biochemical and Biophysical Research Communications, 1991
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Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides
Kaustubh Singh 62
Molecular …, 2009
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A Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent Glucuronidation
nghia nguyen
Drug Metabolism and Disposition, 2010
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Expression and Transport Function of Drug Uptake Transporters in Differentiated HepaRG Cells
C. Chesne
Molecular Pharmaceutics, 2012
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Studies on the cellular pharmacology of N-(4-methylphenylsulfonyl)-N′-(4-chlorophenyl)-urea
Frank Bailey
Biochemical Pharmacology, 1990
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MOAT4, a novel multispecific organic-anion transporter for glucuronides and mercapturates in mouse L1210 cells and human erythrocytes
Manju Saxena
Biochemical Journal, 1996
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The function of the multidrug resistance proteins (MRP and cMRP) in drug conjugate transport and hepatobiliary excretion
Gabriele Jedlitschky
Advances in Enzyme Regulation, 1996
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UDP-Glucuronosyltransferase inhibitors
Evgeny Golovinsky
European Journal of Drug Metabolism and Pharmacokinetics, 1998
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Pharmaceutical Excipients Influence the Function of Human Uptake Transporting Proteins
W. Siegmund
Molecular Pharmaceutics, 2012
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Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): Role of UGT1A1,1A3 and 1A8
Syed Muzeeb , Muzeeb Syed
European Journal of Drug Metabolism and Pharmacokinetics, 2006
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Dependence of glucuronidation rate on UDP-glucuronic acid levels in isolated hepatocytes
Leslie Schwarz
Biochemical Pharmacology, 1981
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Differential expression of several drug transporter genes in HepG2 and Huh-7 cell lines
Frans Suyatna
Advanced Biomedical Research, 2016
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Inward transport of [3H]-1-methyl-4-phenylpyridinium in rat isolated hepatocytes: putative involvement of a P-glycoprotein transporter
maria joao martins
British journal of pharmacology, 1996
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Hepatic, intestinal and renal transport of 1-naphthol-?-d-glucuronide in mutant rats with hereditary-conjugated hyperbilirubinemia
Peter Jansen
Naunyn-Schmiedeberg's Archives of Pharmacology, 1989
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Characterization of Hepatic and Intestinal Glucuronidation of Magnolol: Application of the Relative Activity Factor Approach to Decipher the Contributions of Multiple UDP-Glucuronosyltransferase Isoforms
Hongbo Zhang , Liangliang Zhu , Hui-xin Liu
Drug Metabolism and Disposition, 2012
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Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
ruth hyland
Drug Metabolism and Disposition, 2012
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Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes
Erin Schuetz , Stephen Strom
Pharmacogenetics and Genomics, 2006
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Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
David Howe
Drug Metabolism and Disposition, 2009
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Determination of Drug Glucuronidation and Udp-Glucuronosyltransferase Selectivity Using a 96-WELL Radiometric Assay
Ralph Laufer
Drug Metabolism and Disposition, 2005
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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
Harry Davis
British Journal of Pharmacology, 2000
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Targeted inhibition of glucuronidation markedly improves drug efficacy in mice—A model
Dr Labanyamoy Kole
Biochemical and Biophysical Research Communications, 2007
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Transporters: Importance in Drug Absorption, Distribution, and Removal
Frans Russel
Enzyme- and Transporter-Based Drug-Drug Interactions, 2009
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A cell-based assay for screening the uridine 5′-diphosphate–glucuronosyltransferase 1A inhibitory potential of new chemical entities
Jaime Padros
Analytical Biochemistry, 2003
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Hepatic Transport Mechanisms of Cholyl-L-Lysyl-Fluorescein
Cindy Kunne
Journal of Pharmacology and Experimental Therapeutics, 2010
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