TRPM2 functions as a lysosomal Ca2+-release channel in beta cells (original) (raw)
TRPM2: a multifunctional ion channel for calcium signalling
Adriana Sumoza-Toledo
Journal of Physiology-London, 2011
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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage
Iwona Laszkiewicz
American Journal of Physiology-Cell Physiology, 2005
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TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells
Sharifah Alawieyah Syed Mortadza
Frontiers in immunology, 2015
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NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes
Marisa Brini
Journal of Biological Chemistry, 2012
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Role of TRPM2 in H2O2-Induced Cell Apoptosis in Endothelial Cells
Xiaoqiang Yao
PLoS ONE, 2012
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H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the β-cells: involvement of TRPM2 channels
shahidul islam
Journal of Cellular and Molecular Medicine, 2009
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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase
Stephen Skaper
British Journal of Pharmacology, 2004
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TRPC1 contributes to the Ca2+-dependent regulation of adenylate cyclases
Lorena Maria Alves de souza
Biochemical Journal, 2014
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TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum
Roland Nitschke
The EMBO Journal, 2009
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Role of TRPM2 in cell proliferation and susceptibility to oxidative stress
Iwona Laszkiewicz
American Journal of Physiology-Cell Physiology, 2013
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TRPM7-mediated spontaneous Ca2+entry regulates the proliferation and differentiation of human leukemia cell line K562
隆司 井上
Physiological Reports, 2018
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A differential role of macrophage TRPM2 channels in Ca2+ signaling and cell death in early responses to H2O2
Z Mei
American Journal of Physiology-Cell Physiology, 2013
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TRPM2-mediated Ca2+ signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells
Daniela Calina
Cell Communication and Signaling
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The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation
Tomohiro Numata
The Journal of physiology, 2012
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TRPM4 links calcium signaling to membrane potential in pancreatic acinar cells
János Almássy
Journal of Biological Chemistry, 2021
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Ligand induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg 1433 and Tyr 1349
Andrea Araujo
The Biochemical journal, 2017
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The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate
Jean Prenen
The EMBO Journal, 2006
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Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans
Claudio Cabello-Verrugio, Felipe Simon
Cellular Signalling, 2013
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Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils
Ingo Lange
Cell Calcium, 2008
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Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+-Dependent Toxicity
Lutz Birnbaumer, Y. Mori
Gastroenterology, 2011
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Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy
Iwona Laszkiewicz
Cell Death & Disease
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Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice
Nina Ullrich, Jean Prenen
Cell Calcium, 2005
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Constitutive Activity of the Human TRPML2 Channel Induces Cell Degeneration
Baruch Minke
Journal of Biological Chemistry, 2010
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The transient receptor potential melastatin-2 (TRPM2) channel and inflammation
Gabriela Mellado
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Calcium Entry through TRPV1: A Potential Target for the Regulation of Proliferation and Apoptosis in Cancerous and Healthy Cells
Dietrich Büsselberg
International Journal of Molecular Sciences
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Hydrogen Peroxide Removes TRPM4 Current Desensitization Conferring Increased Vulnerability to Necrotic Cell Death
Ricardo Armisén, Felipe Simon
Journal of Biological Chemistry, 2010
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Contribution of endogenously expressed Trp1 to a Ca2+-selective, store-operated Ca2+ entry pathway
george brough
Faseb Journal, 2001
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Inhibition of TRPM2 cation channels by N -(p -amylcinnamoyl)anthranilic acid
Henning Frenzel
British Journal of Pharmacology, 2009
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TRPM2 Non-Selective Cation Channels in Liver Injury Mediated by Reactive Oxygen Species
Eunus S. Ali, Ph.D.
Antioxidants, 2021
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TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase
Paola Gavazzo
International Journal of Molecular Sciences
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Physiological roles of NAADP-mediated Ca2+ signaling
Antony Galione
Science China Life Sciences, 2011
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