Current Status of Herbal Drug Standards in the Indian Pharmacopoeia (original) (raw)

Review Article: Standardization and Evaluation of Herbal Drugs is Need of the Hour in Present Era

2020

The herbal preparations are being into used from the primordial time throughout the world. Now, maximum people are shifted towards the Ayurveda for the treatment of any affliction. Herbs are also used as side products in the preparation of synthetic medicine. Traditional system of medicine has taken over the place worldwide, hence majority of products are formulated. The increased use of herbal drug, now concerning with its purity and quality of herbal raw material as well as finished product. Purity of the herbal constituent is the main problem faced by the herbal industries. To overcome this issue, WHO has published the certain guidelines for the standardization of the herbal material. To ensure the efficacy, purity and quality control processes, the personnel should himself supervise the standardization processes with uniform rules. The review represents the standardization parameters with the standards value of quality, purity and efficacy.

WHO Guidelines for Standardization of Herbal Drugs

Herbal drugs are being used as medicines from ancient period. The increased use of herbal drugs, and concerns over their safety and efficacy have certainly augmented the need of standardization of these herbal drugs. WHO has set up guidelines for standardization of these drugs, which are used as a standard by the majority of countries. The standardization includes the external (macroscopy/microscopy) as well as internal examination/ash values, extractive values and many other parameters to identify, authentify and study its chemical composition. Standardization of the medicinal plants will ensure indirectly that the plants are conserved for their medicinal and nutritive value. Standardization confirms the safety of the medicinal plant but efficacy has to be judged clinically or in the laboratory. There is a thin line between efficacy and the presence of chemical compounds in the drug. The major hurdle in standardization of the batch to batch variation in the plant compounds. Addition of finer analytical methods of the chemical compounds may help to minimize the variation and give a better resolution of the plant drug. Importance of toxicological examination has increased manifolds as contamination can occurs at various stages, from collection, storage, analysis or processing to extraction of active principles. These parameters should be recorded for years together; their database should be generated, recorded and analyzed statistically to see the difference in quality and quantity of the chemical compounds. Keywords: Standardization, herbal drug, botanical, pharmacological, toxicological, parameters

A Comprehensive Review On Herbal Drug Standardization

American Journal of PharmTech Research

Now days more importance has been given to use medicinal plant products in healthcare system.it fulfills worldwide need of alternative medicine so traditional systems of medicine becomes more and more popular. It involves Proper combination of modern scientific techniques and traditional knowledge. The quality of herbal products is checked through stability testing studies which depends on various factors, such as temperature, humidity, light, oxygen, moisture, other ingredient , microbial contamination, trace metal contamination, leaching from the container, etc. Therefore such studies involves various types of evaluation such as chemical, physical, microbiological, therapeutic and toxicological studies can serve as an important tool in stability studies. Standardization of herbal drugs means confirmation of its identity, Quality and purity. The present study includes review of various standardization parameters with their effectivity towards the quality herbal drugs. Present article also overviews various well-designed methodologies, techniques such as Chromatography, Spectroscopic tech. for the standardization of herbal raw materials and herbal formulations.

Need & Scope of Standardization of herbal medicines -A review

There is increasing awareness and general acceptability of the use of herbal drugs in today's medical practice. The starting materials for about one-half of the medicines we use today come from natural sources. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers and manufacturers disappointment and in some instances fatal consequences. Herbal drug technology is used for converting botanical materials into medicines, where standardization and quality control with proper integration of modern scientific techniques and traditional knowledge is important. For global harmonization WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines are of utmost importance. Standardization of drug means confirmation of its identity, quality and purity throughout all phases of its cycle. This review seeks to need & scope of standardization processes of herbal medicine for good quality assurance.

Need and scope of standardization of herbal medicines -A review

International Journal of Green Pharmacy, 2021

There is increasing awareness and general acceptability of the use of herbal drugs in today's medical practice. The starting materials for about one-half of the medicines we use today come from natural sources. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers and manufacturers disappointment and in some instances fatal consequences. Herbal drug technology is used for converting botanical materials into medicines, where standardization and quality control with proper integration of modern scientific techniques and traditional knowledge is important. For global harmonization WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines are of utmost importance. Standardization of drug means confirmation of its identity, quality, and purity throughout all phases of its cycle. This review seeks to need and scope of standardization processes of herbal medicine for good quality assurance.

Quality Aspects of Herbal Drugs and its Formulation

International Journal of Advanced Research in Science, Communication and Technology

To evaluate a high-quality medicine, herbal compositions must be standardised. The total of all aspects that directly or indirectly influence the safety, efficacy, and acceptance of a drug product is the quality of a herbal drug. The field of herbal drugs and formulations is developing quickly nowadays, and there is still much to learn about the standardisation of these products. However, the lack of a standardised parameter hurts herbal treatment. The primary constraints are the absence of standards for raw materials, processing techniques, and finished goods, product formulas, and absence of quality control standards. To assure the quality, safety, and effectiveness of herbal medicine using contemporary methods, it is required to measure the regulation of herbal medicine.

Herbal drugs: Standards and regulation

Fitoterapia, 2010

The use of herbal drugs for the prevention and treatment of various health ailments has been in practice from time immemorial. Generally it is believed that the risk associated with herbal drugs is very less, but reports on serious reactions are indicating to the need for development of effective marker systems for isolation and identification of the individual components. Standards for herbal drugs are being developed worldwide but as yet there is no common consensus as to how these should be adopted. Standardization, stability and quality control for herbal drugs are feasible, but difficult to accomplish. Further, the regulation of these drugs is not uniform across countries. There are variations in the methods used across medicine systems and countries in achieving stability and quality control. The present study attempts to identify the evolution of technical standards in manufacturing and the regulatory guideline development for commercialization of herbal drugs.

Herbal Drug Standardization: A Systemic Review

Journal of Drug Delivery and Therapeutics

The demand for herbal medicinal products and materials is rising, and maintaining their quality is therefore becoming increasingly important. Numerous physical, chemical, and geographical factors that affect these materials' quality also affect the quality of the herbals. In addition, the quality of herbal materials is becoming increasingly a concern due to adulteration. The quality characteristics of the herbal material the herbal pharmaceuticals are assessed using a variety of chemical and phytochemical tests, analytical techniques, and hyphenated analytical techniques. Formulations made from herbs are now widely accepted as effective treatments for many ailments. the creation of reliable analytical techniques, such as quantitative assessments of marker/bioactive chemicals and other techniques, that can accurately profile the phytochemical makeup. For the manufacture and manufacturing of herbal medications, standardisation is a crucial step in establishing a uniform biological...

STANDARDIZATION AND EVALUATION OF HERBAL MEDICINES LATEST

Standardization of herbal medicines is the process of prescribing a set of standards or inherent characteristics, constant parameters, definitive qualitative and quantitative values that carry an assurance of quality, efficacy, safety and reproducibility. To do so, there must be clear technical methods by which this these objectives can be achieved. Current review has tried to compile and present available official methods of standardization of herbal medicines in simple and clear way to address such gap.