WHO Guidelines for Standardization of Herbal Drugs (original) (raw)

Review Article: Standardization and Evaluation of Herbal Drugs is Need of the Hour in Present Era

2020

The herbal preparations are being into used from the primordial time throughout the world. Now, maximum people are shifted towards the Ayurveda for the treatment of any affliction. Herbs are also used as side products in the preparation of synthetic medicine. Traditional system of medicine has taken over the place worldwide, hence majority of products are formulated. The increased use of herbal drug, now concerning with its purity and quality of herbal raw material as well as finished product. Purity of the herbal constituent is the main problem faced by the herbal industries. To overcome this issue, WHO has published the certain guidelines for the standardization of the herbal material. To ensure the efficacy, purity and quality control processes, the personnel should himself supervise the standardization processes with uniform rules. The review represents the standardization parameters with the standards value of quality, purity and efficacy.

A Comprehensive Review On Herbal Drug Standardization

American Journal of PharmTech Research

Now days more importance has been given to use medicinal plant products in healthcare system.it fulfills worldwide need of alternative medicine so traditional systems of medicine becomes more and more popular. It involves Proper combination of modern scientific techniques and traditional knowledge. The quality of herbal products is checked through stability testing studies which depends on various factors, such as temperature, humidity, light, oxygen, moisture, other ingredient , microbial contamination, trace metal contamination, leaching from the container, etc. Therefore such studies involves various types of evaluation such as chemical, physical, microbiological, therapeutic and toxicological studies can serve as an important tool in stability studies. Standardization of herbal drugs means confirmation of its identity, Quality and purity. The present study includes review of various standardization parameters with their effectivity towards the quality herbal drugs. Present article also overviews various well-designed methodologies, techniques such as Chromatography, Spectroscopic tech. for the standardization of herbal raw materials and herbal formulations.

Need and scope of standardization of herbal medicines -A review

International Journal of Green Pharmacy, 2021

There is increasing awareness and general acceptability of the use of herbal drugs in today's medical practice. The starting materials for about one-half of the medicines we use today come from natural sources. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers and manufacturers disappointment and in some instances fatal consequences. Herbal drug technology is used for converting botanical materials into medicines, where standardization and quality control with proper integration of modern scientific techniques and traditional knowledge is important. For global harmonization WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines are of utmost importance. Standardization of drug means confirmation of its identity, quality, and purity throughout all phases of its cycle. This review seeks to need and scope of standardization processes of herbal medicine for good quality assurance.

Need & Scope of Standardization of herbal medicines -A review

There is increasing awareness and general acceptability of the use of herbal drugs in today's medical practice. The starting materials for about one-half of the medicines we use today come from natural sources. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers and manufacturers disappointment and in some instances fatal consequences. Herbal drug technology is used for converting botanical materials into medicines, where standardization and quality control with proper integration of modern scientific techniques and traditional knowledge is important. For global harmonization WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines are of utmost importance. Standardization of drug means confirmation of its identity, quality and purity throughout all phases of its cycle. This review seeks to need & scope of standardization processes of herbal medicine for good quality assurance.

Herbal Drug Standardization: A Systemic Review

Journal of Drug Delivery and Therapeutics

The demand for herbal medicinal products and materials is rising, and maintaining their quality is therefore becoming increasingly important. Numerous physical, chemical, and geographical factors that affect these materials' quality also affect the quality of the herbals. In addition, the quality of herbal materials is becoming increasingly a concern due to adulteration. The quality characteristics of the herbal material the herbal pharmaceuticals are assessed using a variety of chemical and phytochemical tests, analytical techniques, and hyphenated analytical techniques. Formulations made from herbs are now widely accepted as effective treatments for many ailments. the creation of reliable analytical techniques, such as quantitative assessments of marker/bioactive chemicals and other techniques, that can accurately profile the phytochemical makeup. For the manufacture and manufacturing of herbal medications, standardisation is a crucial step in establishing a uniform biological...

Standardization, evaluation and quantification of herbal drugs by various analytical methods

International Journal of Ayurvedic Medicine

This review article encompasses the various evaluation parameters of standardization of different medicinal plants and its constituents. In today’s life, more and more people of the world are turning towards the use of natural or herbal products as these have very less or negligible side effects. As the use of herbal medicinal products is increasing day by day, the questions regarding their quality are also arising. This is due to lack of parameters for the standardization of these products. There is a need to set different parameters or methods that can help to standardize the herbal medicinal plant materials. Various methods like physical, chemical, biological is used for standardization and quality evaluation of herbal medicinal plants. These methods can act as a basic tool for the quality evaluation of herbal plant materials. Different parameters of standardization are the fundamental tool for evaluating and assuring the quality of the herbal plant material and its products. Thi...

Challenges in standardization in Traditional Medicine / Herbal Drugs

2009

The use of herbs and herbal extracts to treat diseases has stood the test of time. Herbal products/traditional medicine are composed of many constituents and are, therefore, capable of variation. The variability of the plant material is due to different conditions of growth, harvesting, drying, and storage. The polarity of the solvent, the mode of extraction, and the instability of constituents may also influence the composition and quality of the extracts. The quality criteria for herbal/traditional drugs are no doubt based on a clear scientific definition of the raw materials used. To prove the constant composition of herbal preparations, however, adequate analytical methods have to be applied. Depending upon whether the active principle of the plant is known or not, different concepts of standardization have to be applied in order to establish relevant criteria for uniformity. There are several challenges in doing this. The issue of marker content and standardization claims has u...

RECENT ADVANCES IN HERBAL DRUG STANDARDIZATION – A REVIEW

Recently peoples are getting attracted towards herbal medicines due to many advantages. Herbal formulations have reached extensive acceptability as therapeutic agents for several diseases. Although, most of these applications are unorthodox, it is however a known fact that over 80% of the world population depends on herbal medicines and product for healthy living. This rise in the use of herbal product has also given rise to various forms of abuse and adulteration of the products leading to consumers’ and manufacturers’ disappointment and in some instances fatal consequences. The development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analyses of marker/bioactive compounds and other major constituents, is a major challenge to scientists. Standardization is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assurance program for production ...

STANDARDIZATION AND EVALUATION OF HERBAL MEDICINES LATEST

Standardization of herbal medicines is the process of prescribing a set of standards or inherent characteristics, constant parameters, definitive qualitative and quantitative values that carry an assurance of quality, efficacy, safety and reproducibility. To do so, there must be clear technical methods by which this these objectives can be achieved. Current review has tried to compile and present available official methods of standardization of herbal medicines in simple and clear way to address such gap.