Solubility: it's not just for physical chemists (original) (raw)
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Christopher Lipinski
Advanced Drug Delivery Reviews, 1997
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SOLUBILITY DATA for PHARMACEUTICALS
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Journal of pharmaceutical sciences, 2017
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Experimental and computational screening models for prediction of aqueous drug solubility
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Pharmaceutical Research, 2002
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The importance of the accuracy of the experimental data for the prediction of solubility
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Equilibrium solubility measurement of ionizable drugs – consensus recommendations for improving data quality
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Prediction of Partition Coefficients and Permeability of Drug Molecules in Biological Systems with Abraham Model Solute Descriptors Derived from Measured Solubilities and Water-to-Organic Solvent Partition Coefficients
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Toxicity and Drug Testing, 2012
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Partial Solubility Parameters and Solvatochromie Parameters for Predicting the Solubility of Single and Multiple Drugs in Individual Solvents
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Journal of Pharmaceutical Sciences, 1993
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Accuracy of calculated pH-dependent aqueous drug solubility
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European Journal of Pharmaceutical Sciences, 2004
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Contribution of solid-state properties to the aqueous solubility of drugs
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European Journal of Pharmaceutical Sciences, 2006
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Strategies to Address Low Drug Solubility in Discovery and Development
Christopher Porter
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Drug Solubility: Importance and Enhancement Techniques
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Predicting the Solubility of Sulfamethoxypyridazine in Individual Solvents I: Calculating Partial Solubility Parameters
Pilar Bustamante
Journal of Pharmaceutical Sciences, 1989
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ChemInform Abstract: Drug Solubility: Importance and Enhancement Techniques
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In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data
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Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
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Global testing of a consensus solubility assessment to enhance robustness of the WHO biopharmaceutical classification system
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Aqueous Solubility of Crystalline and Amorphous Drugs PDT 2011
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Machine Vision for Enhanced Understanding of Solid-State Impact on Solubility of Drug Compounds
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2021
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Predicting the Solubility of Sulfamethoxypyridazine in Individual Solvents II: Relationship Between Solute—Solvent Interaction Terms and Partial Solubility Parameters
Pilar Bustamante
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Solubility of Drugs, Their Enhancement, Factors Affecting and Their Limitations: A Review
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AqSolDB, a curated reference set of aqueous solubility and 2D descriptors for a diverse set of compounds
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Scientific Data, 2019
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Exploratory analysis of kinetic solubility measurements of a small molecule library
aimee kestranek
Bioorganic & Medicinal Chemistry, 2011
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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System
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The AAPS journal, 2017
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Apparent solubility and dissolution profile at non-sink conditions as predictive parameters for pharmaceutical Quality by Design
Valter Travagli
2012
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Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution
Jean-luc Veuthey
Analytical and Bioanalytical Chemistry, 2009
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Development of Reliable Aqueous Solubility Models and Their Application in Druglike Analysis
George Krudy
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Critical validation of a new simpler approach to estimate aqueous pKa of drugs sparingly soluble in water
Elisabeth Bosch
Analytica Chimica Acta, 2005
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Prediction of pharmaceutical solubilityVia NRTL-SAC and COSMO-SAC
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pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery
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Calculation of drug-like molecules solubility using predictive activity coefficient models
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