A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay (original) (raw)
A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E
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Modulation of Eukaryotic mRNA Stability via the Cap-binding Translation Complex eIF4F
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Phosphorylation of the Eukaryotic Translation Initiation Factor eIF4E Contributes to Its Transformation and mRNA Transport Activities
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A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery
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Ribosome Loading Onto the MRNA Cap is Driven by Conformational Coupling Between EIF4G and EIF4E
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Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap
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Translational Homeostasis via the mRNA Cap-Binding Protein, eIF4E
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eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G
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A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies
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The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled
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Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing
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eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR
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Journal of Cell Biology, 2005
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The Eukaryotic Initiation Factor (eIF) 4G HEAT Domain Promotes Translation Re-initiation in Yeast Both Dependent on and Independent of eIF4A mRNA Helicase
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Eukaryotic Initiation Factor 4E phosphorylation acts a switch for its binding to 4E-BP1 and mRNA cap assembly
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Dominant negative mutants of mammalian eIF-4A define a critical role for eIF-4F in cap-dependent initiation of translation
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Translational activation of uncapped mRNAs by the central part of human eIF4G is 5′ end-dependent
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eIF4E is a central node of an RNA regulon that governs cellular proliferation
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Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation
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Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins
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The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence
Arnim Pause
Molecular and Cellular Biology, 1994
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Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5′ cap
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The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
Sylvie Mader
Molecular and cellular …, 1995
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Nuclear eIF4E Stimulates 3′-End Cleavage of Target RNAs
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Expression of fragments of translation initiation factor eIF4GI reveals a nuclear localisation signal within the N-terminal apoptotic cleavage fragment N-FAG
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Translation driven by an eIF4G core domain in vivo
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RNA-tethering assay and eIF4G:eIF4A obligate dimer design uncovers multiple eIF4F functional complexes
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Intracellular targeting and mRNA interactions of the eukaryotic translation initiation factor eIF4E in the yeast Saccharomyces cerevisiae
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The Yeast Nuclear Cap Binding Complex Can Interact with Translation Factor eIF4G and Mediate Translation Initiation
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