Bcl-2 functionally interacts with inositol 1, 4, 5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1, 4, 5-trisphosphate
Llewelyn Roderick
Science's …, 2004
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Phosphorylation of inositol 1, 4, 5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis
Llewelyn Roderick
Proceedings of the …, 2008
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The Type III Inositol 1,4,5-Trisphosphate Receptor Preferentially Transmits Apoptotic Ca2+ Signals into Mitochondria
Dawidson Gomes
Journal of Biological Chemistry, 2005
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Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals
Llewelyn Roderick
Molecular cell, 2008
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The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage
Thomas Kaufmann
Journal of Biological Chemistry, 2013
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The suppressor domain of inositol 1,4,5-trisphosphate receptor plays an essential role in the protection against apoptosis
Jan Parys
Cell Calcium, 2006
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Inositol 1,4,5-Trisphosphate Receptor Type 1 Is a Substrate for Caspase-3 and Is Cleaved during Apoptosis in a Caspase-3-dependent Manner
Katsuhiko Mikoshiba
Journal of Biological Chemistry, 1999
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Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor
Yiping Rong
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
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Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content
Martin Bootman
Cell Calcium, 2008
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Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl
Giovanni Monaco
Cell Death and Differentiation, 2012
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Calpain-cleaved Type 1 Inositol 1,4,5-Trisphosphate Receptor (InsP3R1) Has InsP3-independent Gating and Disrupts Intracellular Ca2+ Homeostasis
Don-on Mak
Journal of Biological Chemistry, 2011
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The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
ademuyiwa aromolaran
Proceedings of the National Academy of Sciences, 2009
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Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca 2+ release and apoptosis
Tania szado
Proceedings of the National Academy of Sciences of the United States of America, 2008
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Bcl-xL Acts as an Inhibitor of IP3R Channels, Thereby Antagonizing Ca2+-Driven Apoptosis
Nicolas Rosa
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Proteolytic fragmentation of inositol 1,4,5-trisphosphate Receptors: A novel mechanism regulating channel activity?
Kamil Alzayady
The Journal of physiology, 2015
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Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
Scott Oakes, Tullio Pozzan, Joseph Opferman
Proceedings of the National Academy of Sciences, 2005
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Fragmented Inositol 1,4,5-Trisphosphate Receptors Retain Tetrameric Architecture and Form Functional Ca2+ Release Channels
Kamil Alzayady
Journal of Biological Chemistry, 2013
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Distinct Roles of Inositol 1,4,5-Trisphosphate Receptor Types 1 and 3 in Ca2+ Signaling
Takayuki Michikawa
Journal of Biological Chemistry, 2004
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Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors
Mark Philips
Proceedings of the National Academy of Sciences of the United States of America, 2013
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Endoplasmic reticulum, Bcl-2 and Ca 2+ handling in apoptosis
Paolo Pinton, Mounia Chami
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Functions 1,4,5-Trisphosphate Receptor (Type 1) Modulates Inositol Cdc2/Cyclin B1 Interacts with and
Kirk Sperber
2000
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Cell Signalling: IP3 Receptors Channel Calcium into Cell Death
Martin Bootman
Current Biology, 2004
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The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release
5086-HEIKE IVETH GODINEZ GARCIA
The Journal of biological chemistry, 2015
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Region-specific proteolysis differentially regulates type 1 inositol 1,4,5-trisphosphate receptor activity
Kamil Alzayady
Journal of Biological Chemistry, 2017
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Novel Regulation of Calcium Inhibition of the Inositol 1,4,5-trisphosphate Receptor Calcium-release Channel
Don-on Mak
The Journal of General Physiology, 2003
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Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis
Tullio Pozzan
The EMBO Journal, 2004
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Cdc2/cyclin B1 interacts with and modulates inositol 1,4,5-trisphosphate receptor (type 1) functions
Kirk Sperber
Journal of immunology (Baltimore, Md. : 1950), 2005
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Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation
Pompeo Volpe
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
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