Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1 (original) (raw)

Stereoselective uptake of β‐lactam antibiotics by the intestinal peptide transporter

British Journal of Pharmacology, 1995

Modified amino acids and peptides as substrates for the intestinal peptide transporter PepT1

Richard Boyd

European Journal of Biochemistry, 2000

Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1

Michael Bolger

Journal of Controlled Release, 1999

Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids

The Histochemical journal, 1999

Recognition of β-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells

American Journal of Physiology-Renal Physiology, 1997

Minimal Molecular Determinants of Substrates for Recognition by the Intestinal Peptide Transporter

Journal of Biological Chemistry, 1998

Expression and cellular distribution during development of the peptide transporter (PepT1) in the small intestinal epithelium of the rat

Richard Boyd

Cell and Tissue Research, 2002

A Rapid in Vitro Screening for Delivery of Peptide-Derived Peptidase Inhibitors as Potential Drug Candidates via Epithelial Peptide Transporters

Journal of Pharmacology and Experimental Therapeutics, 2004

Dipeptide transport and hydrolysis in rat small intestine, in vitro

Richard Boyd

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1995

Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, ßlactam antibiotics and ACE-inhibitors

Heini Murer

Pflügers Archiv European Journal of Physiology, 1994

Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats

AJP: Gastrointestinal and Liver Physiology, 2005

Structural requirements for intestinal absorption of peptide drugs

Manoj Nerurkar, Teruna J Siahaan, Gregory Knipp

Journal of Controlled Release, 1996

Amino acid absorption and homeostasis in mice lacking the intestinal peptide transporter PEPT1

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2011

Expression profiles of various transporters for oligopeptides, amino acids and organic ions along the human digestive tract

Xiaoyue Pan, Takaki Sakurai, Ken-Ichi Inui

Biochemical Pharmacology, 2005

Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2

Pfl�gers Archiv - European Journal of Physiology, 2004

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

David Thwaites

The Journal of Physiology, 1998

Peptoid transporters: effects of cationic, amphipathic structure on their cellular uptake

Annelise Barron

Molecular BioSystems, 2012

Paracellular transport of a proteolytically labile pentapeptide across the colonic and other intestinal segments of the albino rabbit: implications for peptide drug design

Vincent Lee

Journal of Controlled Release, 1994

Substrate-induced changes in the density of peptide transporter PEPT1 expressed inXenopusoocytes

American Journal of Physiology-Cell Physiology, 2008

Intestinal peptidases form functional complexes with the neutral amino acid transporter B 0 AT1

S. Bröer

Biochemical Journal, 2012

Enhancement of the intestinal absorption of peptides and nonpeptides

Munir Hussain

Journal of Controlled Release, 1996

Current Perspectives on Established and Putative Mammalian Oligopeptide Transporters

Dea Herrera-Ruiz

Journal of pharmaceutical …, 2003

Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line

Carsten Uhd Nielsen, Birger Brodin

Journal of Controlled Release, 2001

Prodrug strategies to enhance the intestinal absorption of peptides

Binghe Wang

Drug Discovery Today, 1997

The in vitro transport of model thiodipeptide prodrugs designed to target the intestinal oligopeptide transporter, PepT1

Myrtani Pieri

Organic & Biomolecular Chemistry, 2009

Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1999

Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues

Dea Herrera-Ruiz

The AAPS Journal, 2001

Effect of N-Glycosylation on the Transport Activity of the Peptide Transporter PEPT1

American journal of physiology. Gastrointestinal and liver physiology, 2015