Bile acid inhibition of P-glycoprotein-mediated transport in multidrug-resistant cells and rat liver canalicular membrane vesicles*1 (original) (raw)

Reversal of multidrug resistance and increase in plasma membrane fluidity in CHO cells with R-verapamil and bile salts

Juergen Dolderer

European Journal of Cancer, 2001

View PDFchevron_right

Influence of bile salts on hepatic mdr2 P-glycoprotein expression

Ronald Elferink

Advances in Enzyme Regulation, 1996

View PDFchevron_right

Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

Stephen Strom

Toxicological …, 2003

View PDFchevron_right

Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma cells in vitro

Laura Earnest

Biochemical Pharmacology, 1991

View PDFchevron_right

Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas

Jozef Glasa

Gastroenterology, 1997

View PDFchevron_right

Further evidence of the usefulness of bile acids as molecules for shuttling cytostatic drugs toward liver tumors

Rocío García Macías

Journal of Hepatology, 1999

View PDFchevron_right

Expression and regulation of hepatic drug and bile acid transporters

André Guillouzo, V. Lecureur

Toxicology, 2000

View PDFchevron_right

Up‐regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down‐regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in …

Michael Muller

…, 1998

View PDFchevron_right

An In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat Hepatocytes

Kenneth Brouwer

Drug Metabolism and Disposition, 2010

View PDFchevron_right

Transport of drugs in isolated hepatocytes the influence of bile salts

Dirk K F Meijer

Biochemical Pharmacology, 1978

View PDFchevron_right

Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: Physiological basis and pathophysiological changes in cholestatic liver dysfunction

Professor Samy Azer

Journal of Gastroenterology and Hepatology, 1996

View PDFchevron_right

Bile acid transport across the hepatocyte canalicular membrane

Frederick Suchy

The FASEB Journal

View PDFchevron_right

The start of a new era in bile physiology

Ronald Elferink

Journal of Hepatology, 2004

View PDFchevron_right

Bile Acid–Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs

Hiroaki Yamaguchi

International Journal of Molecular Sciences

View PDFchevron_right

Absence of glycochenodeoxycholic acid (GCDCA) in human bile is an indication of cholestasis: a 1H MRS study

omkar ijare, Urban Arnelo, Ian Smith

NMR in biomedicine, 2009

View PDFchevron_right

Bile Acids Increase Doxorubicin Sensitivity in ABCC1-expressing Tumour Cells

Amadeo M Parissenti

Scientific Reports

View PDFchevron_right

Bile Acids in Physiology, Pathology and Pharmacology

JOSÉ JUAN GARCÍA MARÍN

Current Drug Metabolism, 2015

View PDFchevron_right

Use of ursodeoxycholic acid in liver diseases

Dinesh Kumar

Journal of Gastroenterology and Hepatology, 2001

View PDFchevron_right

Bile acid-induced liver toxicity: Relation to the hydrophobic-hydrophilic balance of bile acids

Alfredo Cantafora

Medical Hypotheses, 1986

View PDFchevron_right

A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

Paavo Honkakoski

Scientific Reports, 2022

View PDFchevron_right

Bile Acid Transport in Sister of P-Glycoprotein (ABCB11) Knockout Mice

Renxue Wang

Biochemistry, 2005

View PDFchevron_right

Progressive and preferential cellular accumulation of hydrophobic bile acids induced by cholestatic drugs is associated with inhibition of their amidation and sulfation

André Guillouzo

Drug Metabolism and Disposition

View PDFchevron_right

Pharmacology of bile acids and their derivatives: Absorption promoters and therapeutic agents

Momir Mikov

European Journal of Drug Metabolism and Pharmacokinetics, 2006

View PDFchevron_right

Molecular Determinants in the Transport of a Bile Acid-Derived Diagnostic Agent in Tumoral and Nontumoral Cell Lines of Human Liver

Claudio Tiribelli

Journal of Pharmacology and Experimental Therapeutics, 2006

View PDFchevron_right

Transport of bile acids in a human intestinal epithelial cell line, Caco-2

Ismael Hidalgo

Biochimica et Biophysica Acta (BBA) - General Subjects, 1990

View PDFchevron_right

Upregulation of the multidrug resistance genes mrp1 and mdr1b and downregulation of the organic anion transporter mrp2 and bile salt transporter spgp in endotoxemic rat liver

Dirk K F Meijer

European Journal of Gastroenterology & Hepatology, 1998

View PDFchevron_right

Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells

Pedro Gonçalves

Journal of Cellular Biochemistry, 2012

View PDFchevron_right

Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice☆☆☆

Albert Groen, Folkert Kuipers

Gastroenterology, 1998

View PDFchevron_right

Bile Acids and Their Derivatives as Potential Modifiers of Drug Release and Pharmacokinetic Profiles

Momir Mikov

Frontiers in Pharmacology

View PDFchevron_right

Enhanced Expression of the Human Multidrug Resistance Protein 3 by Bile Salt in Human Enterocytes

Takeshi Uchiumi

Journal of Biological Chemistry, 2001

View PDFchevron_right

Species differences in hepatic bile acid uptake: Comparative evaluation of taurocholate and tauroursodeoxycholate extraction in rat and rabbit

Aldo Roda

Comparative Biochemistry and Physiology Part A: Physiology, 1996

View PDFchevron_right

Evidence for a multidrug resistance-associated protein 1 (MRP1)-related transport system in cultured rat liver biliary epithelial cells

Dominique Lagadic-gossmann, André Guillouzo

Life Sciences, 1999

View PDFchevron_right

INFLUENCE OF BILE ACIDS ON THE BILIARY TRANSPORT MAXIMUM OF PHENOLSULPHONPHTHALEIN IN THE RAT

Javier González-Gallego

Clinical and Experimental Pharmacology and Physiology, 1988

View PDFchevron_right

Regulation of MDR2 P-glycoprotein expression by bile salts

Ronald Elferink

Hepatology, 1995

View PDFchevron_right

Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat

Jose Pellegrino

Gut

View PDFchevron_right