Expression and regulation of hepatic drug and bile acid transporters (original) (raw)
Differential Modulation of the Human Liver Conjugate Transporters MRP2 and MRP3 by Bile Acids and Organic Anions
Balazs Sarkadi
Journal of Biological Chemistry, 2003
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Molecular aspects of hepatobiliary transport
Michael Muller
American Journal of Physiology- …, 1997
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Influence of bile salts on hepatic mdr2 P-glycoprotein expression
Ronald Elferink
Advances in Enzyme Regulation, 1996
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Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport
Albert Groen, Folkert Kuipers
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1995
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An In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat Hepatocytes
Kenneth Brouwer
Drug Metabolism and Disposition, 2010
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Drug transport proteins in the liver
Peter Jansen
Advanced Drug Delivery Reviews, 2003
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Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: Physiological basis and pathophysiological changes in cholestatic liver dysfunction
Professor Samy Azer
Journal of Gastroenterology and Hepatology, 1996
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Enterohepatic bile salt transporters in normal physiology and liver disease
Peter Meier
Gastroenterology, 2004
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Bile acid transport across the hepatocyte canalicular membrane
Frederick Suchy
The FASEB Journal
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Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
Jan Wijnholds
Journal of Hepatology, 2006
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Transport of drugs in isolated hepatocytes the influence of bile salts
Dirk K F Meijer
Biochemical Pharmacology, 1978
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Second International Ringberg Conference: "Cell Biology and Molecular Basis of Liver Transport
Rolf Kinne
Hepatology, 1996
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Upregulation of the multidrug resistance genes mrp1 and mdr1b and downregulation of the organic anion transporter mrp2 and bile salt transporter spgp in endotoxemic rat liver
Dirk K F Meijer
European Journal of Gastroenterology & Hepatology, 1998
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Regulation of biliary drug efflux pump expression by hormones and xenobiotics
V. Lecureur
Toxicology, 2001
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Hepatic Transport of Bile Salts
Peter Meier
Seminars in Liver Disease, 2000
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Basolateral and canalicular transport of xenobiotics in the hepatocyte: A review
Gonzalo Diaz
Cytotechnology, 2000
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Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases
G. Krejs, Kurt Zatloukal, Peter Fickert
Hepatology, 2001
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Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes
Rémy Guével
Toxicological sciences : an official journal of the Society of Toxicology, 2015
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Up‐regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down‐regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in …
Michael Muller
…, 1998
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Hepatobiliary transporter expression in human hepatocellular carcinoma
Kurt Zatloukal, Peter Fickert
Liver International, 2005
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Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3−1 and Can 10
JOSÉ JUAN GARCÍA MARÍN
Cell and Tissue Research, 2007
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Molecular Determinants in the Transport of a Bile Acid-Derived Diagnostic Agent in Tumoral and Nontumoral Cell Lines of Human Liver
Claudio Tiribelli
Journal of Pharmacology and Experimental Therapeutics, 2006
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Plasma Membrane Transporters in Modern Liver Pharmacology
JOSÉ JUAN GARCÍA MARÍN
Scientifica, 2012
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Bile acid inhibition of P-glycoprotein-mediated transport in multidrug-resistant cells and rat liver canalicular membrane vesicles*1
roberto Mazzanti
Hepatology, 1994
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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450
Jatinder Lamba
Journal of Biological Chemistry, 2001
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Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats
Stephen Strom
Toxicological …, 2003
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A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development
Ryan Morgan
Toxicological sciences : an official journal of the Society of Toxicology, 2013
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Hepatic vectorial transport of xenobiotics
Gerald LeBlanc
Chemico-Biological Interactions, 1994
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Effects of Ursodeoxycholic and Cholic Acid Feeding on Hepatocellular Transporter Expression in Mouse Liver
Peter Meier
Gastroenterology, 2001
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Bile acid transporters and regulatory nuclear receptors in the liver and beyond
Emina Halilbasic
Journal of Hepatology, 2013
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Genetic defects in hepatobiliary transport
Ronald Elferink
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2002
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Biliary efflux transporters involved in the clearance of rosuvastatin in sandwich culture of primary rat hepatocytes
Katalin Jemnitz
Toxicology in Vitro, 2010
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Selective hepatobiliary transport defect for organic anions and neutral steroids in mutant rats with hereditary-conjugated hyperbilirubinemia
Peter Jansen
Hepatology, 1987
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