Selective glycosidase inhibitors: A patent review (2012-present) (original) (raw)

Tetrahedron report number 773 a-and b-Glucosidase inhibitors: chemical structure and biological activity

man U

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and β-Glucosidase inhibitors: chemical structure and biological activity

Eduardo Melo

Tetrahedron, 2006

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α- and β-Glucosidase Inhibitors: Chemical Structure and Biological Activity

Ivone Carvalho

ChemInform, 2007

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Back to (non-)Basics: An Update on Neutral and Charge-Balanced Glycosidase Inhibitors

Todd Houston

Mini reviews in medicinal chemistry, 2017

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TARGETING GLYCOSYLATION AS A THERAPEUTIC APPROACH

Nicole Zitzmann

Nature Reviews Drug Discovery, 2002

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Back to (non)-Basics: Recent Developments in Neutral and Charge- Balanced Glycosidase Inhibitors

Todd Houston

Mini-Reviews in Medicinal Chemistry, 2003

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Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application

George Fleet

Tetrahedron: Asymmetry, 2000

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Iminosugars as glycosyltransferase inhibitors

Alberto Marra

Organic & Biomolecular Chemistry, 2021

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Synthesis of new six-and seven-membered 1-N-iminosugars as promising glycosidase inhibitors

Sanjay Chavan

Bioorganic & Medicinal …, 2011

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Synthesis of Hybrids of D‐Glucose and D‐Galactose with Pyrrolidine‐Based Iminosugars as Glycosidase Inhibitors

Girish Rawal

European Journal of …, 2008

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Glycosidase inhibitors from the roots of Glyphaea brevis

Abdulmagid Magid, Dominique Harakat

Phytochemistry, 2015

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The Two Faces of Iminoalditols: Powerful Inhibitors Trigger Glycosidase Activation

Current Enzyme Inhibition

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Enzyme Inhibitors as Therapeutic Tools

Mahmoud Balbaa

Biochemistry & Physiology: Open Access, 2012

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Synthesis and evaluation of sulfamide-type indolizidines as glycosidase inhibitors

José Fernández, Anne Wadouachi

Bioorganic & Medicinal Chemistry Letters, 2008

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A drug targeting motif for glycosidase inhibitors: an iminosugar–boronate shows unexpectedly selective β-galactosidase inhibition

Todd Houston

Tetrahedron Letters, 2002

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Synthetic studies in butenonyl C-glycosides: Preparation of polyfunctional alkanonyl glycosides and their enzyme inhibitory activity

Rama P Tripathi

Bioorganic & Medicinal Chemistry Letters, 2009

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Enzyme inhibition by iminosugars: Analysis and insight into the glycosidase–iminosugar dependency of pH

Mikael Bols

Bioorganic & Medicinal Chemistry, 2013

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Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

Andrea Vasella

Journal of the American Chemical Society, 2007

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Cyclic Guanidino-Sugars with Low p K a as Transition-State Analog Inhibitors of Glycosidases: Neutral Instead of Charged Species Are the Active Forms

Jin-hyun Jeong

Journal of the American Chemical Society, 1996

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Solid-phase enzyme-linked assay for the screening of glycosidase activities and inhibitors

Charles Tellier

Biotechnology Techniques

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Glycosyltransferase and Glypiation Inhibitors

Ishtiaq Ahmad

Current Organic Chemistry, 2007

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4-C-Me-DAB and 4-C-Me-LAB—enantiomeric alkyl-branched pyrrolidine iminosugars—are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group

George Fleet

Tetrahedron Letters, 2011

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Improved cellular inhibitors for glycoprotein processing α-glucosidases: biological characterisation of alkyl- and arylalkyl-N-substituted deoxynojirimycins

raymond dwek

Tetrahedron: Asymmetry, 2009

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Potential role of glycosidase inhibitors in industrial biotechnological applications

Laura Camardella

Biochimica Et Biophysica Acta-proteins and Proteomics, 2004

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The Structural Basis of Glycosidase Inhibition by Five‐Membered Iminocyclitols: The Clan A Glycoside Hydrolase Endoglycoceramidase as a Model System

Andrea Vasella

Angewandte Chemie International Edition, 2007

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Synthesis and evaluation as glycosidase inhibitors of 2,5-imino-d-glucitol and 1,5-imino-d-mannitol related derivatives

Matthias Böhm

Bioorganic & Medicinal Chemistry, 2000

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A novel class of glycosidase inhibitors: structures related to australine, lentiginosine, salacinol and swainsonine

Sharwan Kumar

2007

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Synthesis and evaluation of d-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors

Martijn D P Risseeuw

Bioorganic & Medicinal Chemistry Letters, 2009

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Synthesis and evaluation of a bicyclic deo×ymannojirimycin derivative as a potential glycosidase inhibitor

Kelly Tanaka

Canadian Journal of Chemistry-revue Canadienne De Chimie, 1998

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