Pharmacophore and Virtual Screening of JAK3 inhibitors (original) (raw)

Putative dual inhibitors of Janus kinase 1 and 3 (JAK1/3): Pharmacophore based hierarchical virtual screening

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Design of novel JAK3 Inhibitors towards Rheumatoid Arthritis using molecular docking analysis

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In silico identification of natural product inhibitors of JAK2

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The design of a Janus Kinase 3 (JAK3) specific inhibitor 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) allowing for the interrogation of JAK3 signaling in humans

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Discovery of highly potent, selective, covalent inhibitors of JAK3

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Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors

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Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

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Development of an enzyme-coupled activity assay for Janus kinase 2 inhibitor screening

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Integrated Ligand and Structure based approaches towards developing novel Janus Kinase 2 inhibitors for the treatment of myeloproliferative neoplasms

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Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors

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A direct enzyme-linked immunosorbent assay (ELISA) for the quantitative evaluation of Janus Kinase 3 (JAK3) inhibitors

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Computer-Aided Drug Design of Novel Derivatives of 2-Amino-7,9-dihydro-8H-purin-8-one as Potent Pan-Janus JAK3 Inhibitors

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Selective JAK inhibitors

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Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5- d ]pyrrolo[2,3- b ]pyridine Inhibitors

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Targeting JAK3 Tyrosine Kinase-Linked Signal Transduction Pathways with Rationally-Designed Inhibitors

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Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)

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