Distribution of prolactin receptors suggests an intraductal role for prolactin in the mouse and human mammary gland, a finding supported by analysis of signaling in polarized monolayer cultures (original) (raw)

Experimental Gerontology, 2000

The role of Prolactin in human breast cancer

Hamza Mujagic

The role of prolactin in human breast cancer Review

Hamza Mujagic

Biochemia Medica

Prolactin Signaling in Mammary Gland Development

Xiuwen Liu

Journal of Biological Chemistry, 1997

In vivo study of prolactin (PRL) intracellular signalling during lactogenesis in the rat: JAK/STAT pathway is activated by PRL in the mammary gland but not in the liver

Graciela Jahn, N. Daniel

Biology of Reproduction

Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

Jessica Harris

Recent progress in …, 2010

Transcriptional and spatiotemporal regulation of prolactin receptor mRNA and cooperativity with progesterone receptor function during ductal branch growth in the mammary gland

Josephine Trott

Developmental Dynamics, 2001

Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation

Oncogene, 2000

TRIENNIAL LACTATION SYMPOSIUM: Prolactin: The multifaceted potentiator of mammary growth and function

Josephine Trott

Journal of Animal Science, 2012

Expression of Prolactin and Its Receptor in Human Breast Carcinoma 1

Jean-jacques Lebrun

Endocrinology, 1997

Prolactin Mediated Intracellular Signaling in Mammary Epithelial Cells: Prolactin, Growth Hormone, and Placental Lactogen

Nathalie Cella

Journal of Mammary Gland Biology and Neoplasia

Impaired Turnover of Prolactin Receptor Contributes to Transformation of Human Breast Cells

A. Plotnikov

Cancer Research, 2009

Stabilization of prolactin receptor in breast cancer cells

Natalie Minkovsky

Oncogene, 2005

Should prolactin be reconsidered as a therapeutic target in human breast cancer?

Molecular and Cellular Endocrinology, 1999

Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes

Lisa Arendt

Journal of Endocrinology, 2009

Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma

Journal of Endocrinology, 2006

Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERα and STAT5

Oncotarget, 2014

Essential role of endogenous prolactin and cdk7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cells

Oncotarget, 2017

Progesterone receptors (PR) mediate STAT actions: PR and prolactin receptor signaling crosstalk in breast cancer models

Laura Mauro

The Journal of Steroid Biochemistry and Molecular Biology, 2017

Prolactin receptor expression in gynaecomastia and male breast carcinoma

Mariana Mesquita

Histopathology, 2008

Prolactin signal transduction mechanisms in the mammary gland: the role of the Jak/Stat pathway

Christine Watson

Reviews of Reproduction, 1996

Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness

Frontiers in Endocrinology

S2 Deletion Variants of Human PRL Receptors Demonstrate That Extracellular Domain Conformation Can Alter Conformation of the Intracellular Signaling Domain †

Ameae Walker

Biochemistry, 2008

Targeted Expression of the Dominant-Negative Prolactin Receptor in the Mammary Gland of Transgenic Mice Results in Impaired Lactation

Fariel Dif

Endocrinology, 2003

Expression of prolactin receptors in normal canine mammary tissue, canine mammary adenomas and mammary adenocarcinomas

Erika Michel, Iris Reichler

BMC Veterinary Research, 2012

Prolactin Decreases Epidermal Growth Factor Receptor Kinase Activity via a Phosphorylation-dependent Mechanism

Victor Manuel Espinosa Quijano

Journal of Biological Chemistry, 1998

Prolactin Receptor Gene Diversity: Structure and Regulation

Trends in Endocrinology & Metabolism, 1998

From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models

Genetic Analysis: Biomolecular Engineering, 1999

The Short Form of The Prolactin (PRL) Receptor Silences PRL Induction of the β-Casein Gene Promoter

Juan Manuel Berlanga

Molecular Endocrinology, 1997

Prolactin Drives Estrogen Receptor-α-Dependent Ductal Expansion and Synergizes with Transforming Growth Factor-α to Induce Mammary Tumors in Males

Lisa Arendt

The American Journal of Pathology, 2008

Pseudophosphorylated prolactin (S179D PRL) inhibits growth and promotes β-casein gene expression in the rat mammary gland

Lili Coss

Cell and Tissue Research, 2002

Activation of the unliganded estrogen receptor by prolactin in breast cancer cells

Ana Aranda

Oncogene, 2009

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

Christine Bole-feysot

Endocrine Reviews, 1998

IGF-2 Is a Mediator of Prolactin-Induced Morphogenesis in the Breast

Gian-paolo Dotto

Developmental Cell, 2002

Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors

Proceedings of the National Academy of Sciences, 2008