Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation (original) (raw)
The role of prolactin in human breast cancer Review
Hamza Mujagic
Biochemia Medica
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Involvement of prolactin in breast cancer: redefining the molecular targets11Abbreviations: PRL, prolactin; PRLR, PRL receptor; GH, growth hormone; JAK, Janus kinase; STAT, signal transducer and activator of transcription; MAPK, Mitogen–activated protein kinase; PI 3-K, Phosphoinositide 3-kinase;...
Vincent Goffin
Experimental Gerontology, 2000
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Should prolactin be reconsidered as a therapeutic target in human breast cancer?
Vincent Goffin
Molecular and Cellular Endocrinology, 1999
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Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes
Lisa Arendt
Journal of Endocrinology, 2009
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Prolactin and human breast cancer: a review
tvrtko bosnic
European Journal of Cancer, 1979
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The role of prolactin in human breast cancer
Hamza Mujagic
2009
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Prolactin Drives Estrogen Receptor-α-Dependent Ductal Expansion and Synergizes with Transforming Growth Factor-α to Induce Mammary Tumors in Males
Lisa Arendt
The American Journal of Pathology, 2008
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Expression of Prolactin and Its Receptor in Human Breast Carcinoma 1
Jean-jacques Lebrun
Endocrinology, 1997
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Prolactin as a local growth promoter in patients with breast cancer: GCRI experience
Nandita Ghosh
European Journal of Surgical Oncology (EJSO), 2000
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Prolactin Drives Estrogen Receptor- -Dependent Ductal Expansion and Synergizes with Transforming Growth Factor- to Induce Mammary Tumors in Males
Lisa Arendt
Amer J Pathol, 2008
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Impaired Turnover of Prolactin Receptor Contributes to Transformation of Human Breast Cells
A. Plotnikov
Cancer Research, 2009
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Effects of Mammary Surgery on Prolactin Secretion in Common and in Triple Negative Breast Cancer Patients
Roberto Trampetti
ARC Journal of Gynecology and Obstetrics
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Stabilization of prolactin receptor in breast cancer cells
Natalie Minkovsky
Oncogene, 2005
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Prolactin receptor expression in gynaecomastia and male breast carcinoma
Mariana Mesquita
Histopathology, 2008
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TRIENNIAL LACTATION SYMPOSIUM: Prolactin: The multifaceted potentiator of mammary growth and function
Josephine Trott
Journal of Animal Science, 2012
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Increased Expression of Prolactin Receptor Gene Assessed by Quantitative Polymerase Chain Reaction in Human Breast Tumors Versus Normal Breast Tissues
Jean-françois Martini
The Journal of Clinical Endocrinology & Metabolism, 1998
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Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions
James Kench
Oncogene, 2007
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The Expression of Prolactin Receptors in Benign Breast Tumors Is Not Associated with Serum Prolactin Level
Roman Moskalenko
Journal of Clinical Medicine, 2021
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Progesterone receptors (PR) mediate STAT actions: PR and prolactin receptor signaling crosstalk in breast cancer models
Laura Mauro
The Journal of Steroid Biochemistry and Molecular Biology, 2017
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Distribution of prolactin receptors suggests an intraductal role for prolactin in the mouse and human mammary gland, a finding supported by analysis of signaling in polarized monolayer cultures
Saudade Andre
Cell and Tissue Research, 2011
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Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors
Vincent Goffin
Proceedings of the National Academy of Sciences, 2008
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Suppression of Breast Cancer by Small Molecules That Block the Prolactin Receptor
Eric Hugo
Cancers
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Prolactin induces ERα-positive and ERα-negative mammary cancer in transgenic mice
Lisa Arendt
Oncogene, 2003
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Prolactin Signaling in Mammary Gland Development
Xiuwen Liu
Journal of Biological Chemistry, 1997
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A 20-Year Prospective Study of Plasma Prolactin as a Risk Marker of Breast Cancer Development
Xuehong Zhang
Cancer Research, 2013
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Activation of the unliganded estrogen receptor by prolactin in breast cancer cells
Ana Aranda
Oncogene, 2009
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Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma
Vincent Goffin
Journal of Endocrinology, 2006
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Biological Significance of Prolactin in Gynecologic Cancers
Anna Lokshin, Vera Levina
Cancer Research, 2009
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Expression of prolactin receptors in normal canine mammary tissue, canine mammary adenomas and mammary adenocarcinomas
Erika Michel, Iris Reichler
BMC Veterinary Research, 2012
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Prolactin as a mammalian mitogen and tumor promoter
Charles Putnam
Advances in Enzyme Regulation, 1988
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Prolactin drives estrogen receptor-alpha-dependent ductal expansion and synergizes with transforming growth factor-alpha to induce mammary tumors in males
Lisa Arendt
The American journal of pathology, 2008
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Transcriptional and spatiotemporal regulation of prolactin receptor mRNA and cooperativity with progesterone receptor function during ductal branch growth in the mammary gland
Josephine Trott
Developmental Dynamics, 2001
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The Role of Prolactin Receptor in GH Signaling in Breast Cancer Cells
John Langenheim
Molecular Endocrinology, 2013
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Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer
Lisa Arendt
Breast Cancer Research, 2011
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Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness
Maria Dufau
Frontiers in Endocrinology
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