Molecular Mechanism of Improved Structural Integrity of Protein in Polymer Based Microsphere Delivery System (original) (raw)

Prevention of structural perturbations and aggregation upon encapsulation of bovine serum albumin into poly(lactide-co-glycolide) microspheres using the solid-in-oil-in-water technique

Kai Griebenow

Journal of Pharmacy and Pharmacology, 2001

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Encapsulation of bovine serum albumin in poly(lactide-co-glycolide) microspheres by the solid-in-oil-in-water technique

Kai Griebenow

Journal of Pharmacy and Pharmacology, 2001

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Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres

Siddharth Jhunjhunwala

Journal of Controlled Release, 2010

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Evaluation of sucrose esters as alternative surfactants in microencapsulation of proteins by the solvent evaporation method

Nga Nguyen

AAPS PharmSci, 2003

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Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers

Kai Griebenow

Journal of Pharmacy and Pharmacology, 2002

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The influence of protein solubilisation, conformation and size on the burst release from poly(lactide-co-glycolide) microspheres

Farahidah Mohamed

Journal of Controlled Release, 2005

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Improved Enzyme Activity and Stability in Polymer Microspheres by Encapsulation of Protein Nanospheres

Kai Griebenow

AAPS PharmSciTech, 2012

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Characterization and morphological analysis of protein-loaded poly (lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique

Carlos Andrés

Journal of Controlled …, 1994

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Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein

Kai Griebenow

Journal of Controlled Release, 2001

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Reduction of structural perturbations in bovine serum albumin by non-aqueous microencapsulation

Kai Griebenow

Journal of Pharmacy and Pharmacology, 2001

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Influence of Different Excipients and Protein Characteristics on Their Susceptibility to Microencapsulation Process

Antonio Carlos

2014

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Characterization and morphological analysis of a cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method

Bernard Roques

Journal of Controlled Release, 1997

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Effect of the molecular weight of poly(ethylene glycol) used as emulsifier on α-chymotrypsin stability upon encapsulation in PLGA microspheres

giselle rico

Journal of Pharmacy and Pharmacology, 2005

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Nano-encapsulation of protein using an enteric polymer as carrier

jose B.ramon

IEE Proceedings - Nanobiotechnology, 2005

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Stabilization of Proteins by Nanoencapsulation in Sugar-Glass for Tissue Engineering and Drug Delivery Applications

Rocky Tuan

Advanced Materials, 2011

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Polysaccharides-based spray-dried microspheres for maintained stability and controlled release of protein

Dae-duk Kim

Journal of Pharmaceutical Investigation, 2012

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A method to tune the shape of protein-encapsulated polymeric microspheres OPEN

Edmondo Battista

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Structuring of lipid phases using controlled heteroaggregation of protein microspheres in water-in-oil emulsions

musa baloch

Journal of Food Engineering, 2013

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Development of polylactide microspheres for protein encapsulation and delivery

Thomas Chandy

Journal of Applied Polymer Science, 2002

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Electrospun Chitosan Microspheres for Complete Encapsulation of Anionic Proteins: Controlling Particle Size and Encapsulation Efficiency

JI SEONG CHOI

AAPS PharmSciTech, 2013

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A method to tune the shape of protein-encapsulated polymeric microspheres

Chiara Attanasio, Renato Alteriis, Massimiliano Porzio, Raffaele Vecchione, Edmondo Battista

Scientific Reports, 2015

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Technological considerations related to the up-scaling of protein microencapsulation by spray-drying

Hans Merkle

European Journal of Pharmaceutics and Biopharmaceutics, 2000

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Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-in-oil-in-water method

Kai Griebenow

International journal of pharmaceutics, 2002

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Reservoir-Type Microcapsules Prepared by the Solvent Exchange Method: Effect of Formulation Parameters on Microencapsulation of Lysozyme

Mingli Ye

Molecular Pharmaceutics, 2006

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Structuring lipids by aggregation of acidic protein microspheres in W/O emulsions

musa baloch

LWT - Food Science and Technology, 2013

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Macromolecular confinement of therapeutic protein in polymeric particles for controlled release: insulin as a case study

Camile Mascarenhas

Brazilian Journal of Pharmaceutical Sciences

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Novel composite microparticles for protein stabilization and delivery

Stefano Giovagnoli, Paolo Blasi

European Journal of Pharmaceutical Sciences, 2009

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FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres1An article of related interest has been published by Yang et al. in J. Pharm. Sci., 88(2), Feb. 1999, accepted Nov. 1998.1

Kai Griebenow

Journal of Controlled Release, 1999

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Development of double emulsion nanoparticles for the encapsulation of bovine serum albumin

Sebastian Cavalitto

Colloids and surfaces. B, Biointerfaces, 2017

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