Evaluation of Role of Hyaluronic Acid in Management of Post Operative Sequale of Mandibular Third Molar Disimpaction - a Split-Mouth Comparative Study (original) (raw)
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Al-Azhar Journal of Dental Science
Objectives: The aim of the study was to assess the efficacy of hyaluronic acid gel on postoperative, dry socket, pain, trismus and edema after extraction of impacted lower third molars. Subjects and methods: Twenty impacted lower third molar teeth were extracted in ten patients under local anesthesia and under aseptic precautions. Split mouth design was followed. According to random allocation, 0.8% HA gel placed into the extraction socket in one side (group 1), while in the other side (group 2), only a gauze pack was placed. Dry socket, pain, trismus and edema were recorded after 24 hours, 72 h, one week and two weeks postsurgery. Results: There was no statistically significant difference in the incidence of dry socket between both groups. The pain score of patients in group 1 was significantly lower than patients in group 2 in all follow up intervals. Trismus was significantly higher in group 1 than group 2 in all intervals. The patients in group 1 have significantly less edema than patients in group 2 in all follow up intervals. Conclusion: Hyaluronic acid 0.8% gel application after extraction of impacted mandibular third molars has no significant effect on the incidence of dry socket, but it has a positive effect on postoperative pain, trismus and swelling.
International Journal of Research in Pharmaceutical Sciences
The surgical removal of third molar is the commonly performed procedure in oral and surgery. It takes several days to recover from the complications following removal of the third molar. The common postoperative complications are pain, swelling, , alveolar after third molar removal The aim of this systematic review was to thoroughly the existing literature to evaluate the effect of socket versus extra socket application of acid gel in management of postoperative complications after third molar removal. The objective of this systematic review is to assess the efficacy of socket versus extra socket application of acid gel compared to placebo or no treatment in management of post-operative complications after removal of third molar.The data bases of PubMed, and google scholar were searched for the related topics along with a complimentary manual search of all oral surgery journals till October 2018.The data collection form was based on analysis of included studies for their quality ass...
Background: Removal of impacted third molars is associated with postoperative complications such as pain, swelling, ecchymosis, trismus, infection, and hematoma. Thus, contemporary surgery aims to reduce complications by applying collagen or hyaluronic acid in the socket after extracting the impacted mandibular third molars.This study aimed to study the efficacy of Hyaluronic Acid (HA) addition to collagen, compared to collagen application alone, on the magnitude of swelling and trismus following impacted mandibular third molar surgery.Methods: About 20 patients underwent impacted bilateral lower third molars surgery (n = 40). Opaque envelopes carried out randomization; two materials were applied topically in the socket collagen alone or with hyaluronic. The post-operative mouth-opening limitation and swelling rate were assessed on the third and seventh days after the extraction. Results: The mean age was 22.7 ± 3.079 years (75% female, 25% male). A statistically significant differe...
2018
Aim and objective: The aim of this study was compare the efficacies of two oral sprays in reducing swelling, pain, and trismus after the extraction of impacted mandibular third molars. Materials and method: This prospective double-blind, randomized, crossover clinical trial included 30 patients with bilateral symmetrically impacted mandibular third molars of similar surgical difficulty. Hyaluronic acid or Normal saline spray was applied (two pumps) to the extraction area, three times daily for 7 days. Swelling was evaluated using a tape measure method, pain with a visual analogue scale (VAS), and trismus by measuring the maximum inter-incisal opening. Assessments were made on the day of surgery and on days 2 and 7 after surgery. Result: Statistically significant differences were detected for the swelling and trismus values between the two treatment groups on the second postoperative day (P = 0.000 and P = 0.024, respectively). However, there was no statistically significant differen...
Effect of Hyaluronic Acid Gel on Healing of Simple Dental Extraction Sockets: A Pilot Study
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: Hyaluronic acid (HA) was explored as a powerful positive biocompatible material that participates in numerous biological processes related to morphogenesis and tissue healing. AIM: In this context, we elevated in this pilot study the effect of HA on soft tissue healing and bone repair of dental sockets (DS) as well as the postoperative pain. MATERIALS AND METHODS: Ten individuals of both genders (80% females and 20% males) with age range 18–44 years, were included who were diagnosed with two non-restorable teeth (total sockets n = 20). A split-mouth study design was performed where the DS of each patient were divided into Group A (study group): Topical oral HA gel (Gengigel®) was applied into sockets while Group B (control group): Sockets were left untreated. Study variables were evaluated including socket length, socket healing scores (healing index), and post-operative pain in both groups at day 1, 5, and 10 for each patient. RESULTS: There were no statistically signif...
European journal of oral implantology, 2008
To evaluate the efficacy of hyaluronic acid to improve the healing of surgical incisions in the oral cavity. Six Italian private practices participated in this trial, each centre provided 12 patients. After suturing, patients were randomised to receive either a single application of 0.8% hyaluronic acid or a placebo (the carrier). Outcome measures were: assessment of wound healing 10 days post-operatively on a Likert scale by the blind operators and by an independent and blinded outcome assessor on the photographs, adverse events and post-operative complications. Reproducibility was assessed by evaluating agreement between operators and the independent outcome assessor using the weighted Kappa statistic. Thirty-six patients were evaluated in each group, at ten days none had dropped-out. No post-operative complications or adverse events occurred. There were no statistically significant differences for wound healing, assessed clinically by the blinded operators or on photographs evalu...
Surgical extraction of impacted lower wisdom teeth is a frequent minor intraoral surgical process. It is regularly linked with aching and postoperative consequences as pain and swelling. The aim of this study is to evaluate the efficacy of two methods in reducing swelling and pain subsequent to the removal of impacted wisdom teeth. This randomized study incorporated 20 patients with impacted wisdom teeth of different surgical complexity. Topical hyaluronic acid gel 2g/2ml with aloe vera (Kin®Care) was given to the patients to be applied to the surgical area three times a day, or diclofenac sodium tablet 50mg (Voltaren®) to be taken every eight hours, for one week. Swelling was estimated using a strip gauge technique, and pain with a visual analogue scale. Evaluations were made on day one of surgical treatment and on 72hrs and one week later. Statistically no significant differences were identified regarding the swelling and pain values between the two treatment groups on the third and seventh day after surgery. Hyaluronic acid gel was as efficient as diclofenac tablets in reducing the two parameters. The use of hyaluronic acid may be advantageous in medically compromised patient such as those with hypertension, chronic asthma, gastric ulcers or in those with any contraindications to using non-steroidal anti-inflammatory drugs, or in pregnant patients to reduce pain and swelling subsequent to impacted wisdom teeth surgery.
Hyaluronic acid: Perspectives in dentistry. A systematic review
International journal of immunopathology and pharmacology, 2016
To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the soft periodontal tissue, gingiva, and periodontal ligament as well as to the hard tissue such as alveolar bone and cementum. Topical hyaluronic acid (HA) has recently been recognized as an adjuvant treatment for chronic inflammatory disease in addition to its use to improve healing after dental procedures. The aim of our work was to systematically review the published literature about potential effects of HA as an adjuvant treatment for chronic inflammatory disease, in addition to its use to improve healing after common dental procedures. Relevant published studies were found in PubMed, Google Scholar, and Ovid using a combined keyword search or medical subject headings. At the end of our study selection process, 25 relevant publications were included, three of them regarding gingivitis, 13 of them relating to chronic periodontitis, seven of them relating to dental surgery, i...