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Elisa Nuti
Molecules
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In silico development of broad spectrum antibacterial by targeting peptide deformylase
Asif Khursheed
2013
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Virtual Screening Approach of Bacterial Peptide Deformylase Inhibitors Results in New Antibiotics
Hanane Boucherit, Sezer Okay
Molecular informatics, 2017
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Zinc-selective inhibition of the promiscuous bacterial amide-hydrolase DapE: implications of metal heterogeneity for evolution and antibioticdrug design
Marc Creus
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N-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity
Raviraj Kulathila
Antimicrobial Agents and Chemotherapy, 2002
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Structural Basis for the Design of Antibiotics Targeting Peptide Deformylase
Dehua Pei
Biochemistry, 1999
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Targeting Metalloenzymes for Therapeutic Intervention
benjamin dick
Chemical reviews, 2018
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Peptide Deformylase: A New Target in Antibacterial, Antimalarial and Anticancer Drug Discovery
firoz khan
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Exploring and Expanding the Coordination Chemistry of Metal-Binding Pharmacophores for Metalloenzyme Inhibition
benjamin dick
2020
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Discovery of Potential Plant-Derived Peptide Deformylase (PDF) Inhibitors for Multidrug-Resistant Bacteria Using Computational Studies
Amir Zeb
Journal of Clinical Medicine, 2018
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Bill Hodnick
Chemical Communications, 2013
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REVOLUTIONIZING ANTIMICROBIAL DRUG DISCOVERY: COMPUTATIONAL DESIGN AND ADMET STUDIES OF EMERGING POTENT ANTI-MICROBIAL AGENTS Original Article
International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)
International Journal of Pharmacy and Pharmaceutical Sciences, 2023
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Hualong Song
Chemical Science, 2019
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AIM-1: An Antibiotic-Degrading Metallohydrolase That Displays Mechanistic Flexibility
Gerhard Schenk
Chemistry (Weinheim an der Bergstrasse, Germany), 2016
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A unique peptide deformylase platform to rationally design and challenge novel active compounds
Thierry Meinnel
Scientific Reports, 2016
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The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening
Gerhard Schenk
Bioorganic & Medicinal Chemistry Letters, 2011
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Peptide Deformylase Inhibitors as Antibacterial Agents: Identification of VRC3375, a Proline-3-Alkylsuccinyl Hydroxamate Derivative, by Using an Integrated Combinatorial and Medicinal Chemistry Approach
Zhi-Jie Ni
Antimicrobial Agents and Chemotherapy, 2004
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Synthesis and kinetic testing of new inhibitors for a metallo-βlactamase from< i> Klebsiella pneumonia and< i> Pseudomonas aeruginosa< sup> 1
Peter Vella
European Journal of …, 2011
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Antibiotic Activity and Characterization of BB3497, a Novel Peptide Deformylase Inhibitor
ANDANI LEONAH
Antimicrobial Agents and Chemotherapy, 2001
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The Crystal Structure of Mitochondrial (Type 1A) Peptide Deformylase Provides Clear Guidelines for the Design of Inhibitors Specific for the Bacterial Forms
Thierry Meinnel
Journal of Biological Chemistry, 2005
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Molecular Recognition by Escherichia coli UDP-3- O -( R -3-hydroxymyristoyl)- N -acetylglucosamine Deacetylase Is Modulated by Bound Metal Ions †
Marcy Hernick
Biochemistry, 2006
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Peptide Aldehyde Inhibitors of Bacterial Peptide Deformylases
Stephan Grant
Archives of Biochemistry and Biophysics, 1999
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Deformylase as a novel antibacterial target
Joaquim Trias
Drug Discovery Today, 2001
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Antibacterial Agents That Target Lipid A Biosynthesis in Gram-negative Bacteria. INHIBITION OF DIVERSE UDP-3-O-(R-3-HYDROXYMYRISTOYL)-N-ACETYLGLUCOSAMINE DEACETYLASES BY SUBSTRATE ANALOGS CONTAINING ZINC BINDING MOTIFS
Taketo Uchiyama
Journal of Biological Chemistry, 2000
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UDP-3- O -( R -3-Hydroxymyristoyl)- N -acetylglucosamine Deacetylase of Escherichia coli Is a Zinc Metalloenzyme †
James E Penner-Hahn
Biochemistry, 1999
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Finding the gems using genomic discovery: antibacterial drug discovery strategies – the successes and the challenges
David Holmes
Drug Discovery Today: Therapeutic Strategies, 2004
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Peptide Deformylase As An Antibacterial Drug Target: Target Validation and Resistance Development
christian hubschwerlen
Antimicrobial agents …, 2001
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Targets and assays for discovering novel antibacterial agents
Elena Raimondi, Margherita Sosio
Journal of Biotechnology, 2002
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Metal Complexes as a Promising Source for New Antibiotics
Christopher Dowson
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Structural genomics of highly conserved microbial genes of unknown function in search of new antibacterial targets
Karsten Suhre
Journal of Structural and Functional Genomics, 2003
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Antibacterial Drug Discovery: Some Assembly Required
Ruben Tommasi
ACS Infectious Diseases, 2018
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