Effects of cigarette smoking on male fertility (original) (raw)
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PubMed, 2005
In this prospective study we investigated different semen parameters of infertile smokers with a history of cigarette smoking. 27 infertile men who smoked cigarettes, 79 infertile men who were nonsmokers and 82 healthy nonsmoking donors were evaluated. Smokers had significantly less spermatozoa with motility grade B (9.37% versus 11.9%, p<0.05), decreased results of hypoosmotic swelling test (46.39% versus 52.11%, p<0.05) than nonsmokers infertile men. The concentration of leukocytes in semen was significantly higher in smokers (0.26 mln/ml versus 0.11 mln/ml, p>0.05), which can also suggests oxidative imbalance in the ejaculates of these men. No differences were found in the assessment of sperm concentration, motility grade A, C, D, percentage normal forms and different sperm defects, induced acrosomal reaction and acidic aniline blue staining test between these two groups (p>0.05). Our data demonstrate that cigarette smoking alters semen quality which could worsen fertilizing capability in infertile men.
IOSR Journal of Dental and Medical Sciences, 2016
Background: Cigarette smoking is a widely recognized health hazard, yet despite worldwide antismoking campaigns, some people continue to consume cigarettes on a regular basis. Likewise prevalence of infertility is also in increasing trend, and among the various cause cigarette smoking in one of the important cause for male infertility. So the present study was conducted objectives of, to assess how much is the impact of the various level of smoking on semen quality parameters in infertile males. Methodology: Infertile males were selected in two groups smokers and Non-smokers which was referred from infertility clinic of Govt Medical college, Nagpur to dept of physiology for their semen analysis. Results: There was statistically significant difference was observed between various level of smoking and Nonsmokers for the sperm count, motility and morphology. Conclusion: the present study shows that smoking adversely affects the quality of semen, seminal parameters like sperm count, motility and morphology affected mostly; which are responsible for the normal fertility.
Role of Smoking in Male Infertility
Perceptions in Reproductive Medicine, 2021
Objectives: Cigarette smoking is associated with subfertility in males and may lead to a decrease in sperm concentration, lower sperm motility, and a reduced percentage of morphologically normal sperms. The objective of the study is to find out the effect of smoking with semen parameters and the relationship between amount of cigarette smoking and semen parameters. Method: This is a hospital-based cohort study conducted in the Infertility clinics of NEIGRIHMS from December 2019 for a period of 1year. 254 male partners were enrolled for the study. Routine semen analysis was carried out under light microscopy according to WHO guidelines.2010. Data was analysed to find out relation of smoking with semen parameters and the relationship between amount of cigarette smoking per day and semen parameters by using SPSS Software Version 21. Result: In the one-year period we had 140 cases of non-smoker and 114 cases of smokers. On analysis of the findings of sperm count, smokers have relative risk of 2.45 of getting oligozoospermia (p value=0.0005). Smokers have relative risk of 1.5 of having total motility <50%. For progressive motility, smokers have relative risk of 2.01 of getting progressive motility<32%. No dose relationship with abnormal semen parameter. Conclusion: Smoking affected sperm count, and total and progressive motility but there was no dose and effect relationship between number of cigarettes per day and its affect on semen parameter.
The effect of cigarette smoking on the semen parameters of infertile men
Gynecological Endocrinology, 2020
Introduction: 36.9% of men worldwide use tobacco. Previous studies suggest a negative effect of cigarette smoking on semen quality, but the results are contradictory. We have studied the effects of smoking on the semen characteristics such as sperm concentration, semen volume, sperm motility, sperm vitality and sperm morphology in a large group of infertile men. Methods: This retrospective study was conducted on a total of 5146 infertile men with at least one year of idiopathic infertility, who admitted to the Centre for Reproductive medicine (CRG) at the Brussels University Hospital, Belgium between 2010 and 2017. The smokers were classified as mild (1-10 cigarettes/d), moderate (11-20 cigarettes/d) or heavy smokers (> 20 cigarettes/d). Semen analysis was performed for all patients. Statistical analysis was performed using the R software package and t-test or Mann-Whitney U tests were used, group comparisons were performed using ANOVA, ANCOVA or Kruskal-Wallis tests as appropriate. A p-value <0.05 was considered as statistically significant. Results: Comparing the semen parameters in the two global groups showed that smoking had a significant decrease in semen volume (p¼0.04074) and sperm concentration (p¼0.029). ANOVA testing on the different smoking groups versus non-smoking group showed a significant decrease in sperm concentration (p¼0.0364). After adjusting for the confounders, age and testosterone, ANCOVA testing showed significant effect on the sperm concentration (p¼0.03871) in smokers versus non-smokers. No significant correlation was detected between the other semen characteristics. Conclusion: We concluded that smoking had a significant and independent effect on the sperm concentration in a semen analysis. Other parameters, like semen volume, sperm motility, sperm vitality and sperm morphology were not influenced by smoking.
Significant Effects of Smoking Habit on Male Fertility
Bahrain Medical Bulletin, 2013
Background: Smoking is a common health problem worldwide. Many diseases and life threatening conditions have been linked to smoking habits, such as, lung cancer, oral cancer, bronchitis and several gastrointestinal disorders. Infertility link to smoking is still under intensive investigation.
Journal of Drug Delivery and Therapeutics, 2020
Background : Cigarette smoking has negative effects on male fertility. Toxins from tobacco smoking can potentially affect sperm development and function, with a negative effect on semen parameters. In fact, the components of cigarette smoke pass through the blood-testis barrier and thus induce an alteration of sperm parameters and nucleus quality of the spermatozoa. The aim is to determine a diffence between tobbaco and no tobbaco patient and semen parameters. This article aimed to assess the relationship between smoking and male infertility. Subject and Methods : this is retrospective study focused on the effects of smoking on semen analyses. 377 men (165 non-smokers, 212 smokers) with infertility for at least 1 year were evaluated between Mars and November 2018, in center of algiers (capital of Algeria). Sperm characteristics (concentration, motility, morphology, and volume) were detemined. Results: Sperm concentration, percentage motility and morphology were significantly lo...
The Influence of Cigarette Smoking on Sperm Quality and Sperm Membrane Integrity
Current Women s Health Reviews, 2016
This study aimed to examine the effects of smoking cigarettes on the sperm feature of healthy, normospermia and subnormospermia men. 420 samples of semen were derived from healthy patients and categorized into two groups; normospermia (G. I, n=100; A: smokers=50, B: non-smokers=50) and subnormospermia (G.II; n=320; A: smokers=160, B: non-smokers=160). Semen analysis was performed for all samples. Sperm vitality was assessed with Eosin test and Hypo-osmotic swelling test (HOS-Test) and was utilized to test the membrane integrity of the sperm. It was determined that heavy smoking (greater than 20 cigarettes per day) was significantly correlated with a decrease in sperm concentration (mill/ml), percentage of vitality (%), motility (%) and membrane integrity in all examined semen samples as well as sample from normo-and subnormosperrmia. These results propose that heavy smoking causes to a significant deterioration in semen quality (sperm concentration, vitality, motility and membrane integrity not only by subnormospermia but also by normospermia men), thus smoking may negatively affect the fertilization efficiency. Sperm cell membrane integrity test (HOS-test) could be used as standard screening test and a biomarker for the sperm quality in patients.