Role of Smoking in Male Infertility (original) (raw)
Related papers
IOSR Journal of Dental and Medical Sciences, 2016
Background: Cigarette smoking is a widely recognized health hazard, yet despite worldwide antismoking campaigns, some people continue to consume cigarettes on a regular basis. Likewise prevalence of infertility is also in increasing trend, and among the various cause cigarette smoking in one of the important cause for male infertility. So the present study was conducted objectives of, to assess how much is the impact of the various level of smoking on semen quality parameters in infertile males. Methodology: Infertile males were selected in two groups smokers and Non-smokers which was referred from infertility clinic of Govt Medical college, Nagpur to dept of physiology for their semen analysis. Results: There was statistically significant difference was observed between various level of smoking and Nonsmokers for the sperm count, motility and morphology. Conclusion: the present study shows that smoking adversely affects the quality of semen, seminal parameters like sperm count, motility and morphology affected mostly; which are responsible for the normal fertility.
Effect of Tobacco Smoking on Semen Quality in Men With Subfertility
UroToday International Journal, 2011
Smoking is considered a risk factor for male infertility, but studies have not shown a conclusive reduction in fertility associated with paternal smoking. The aim of the present study was to investigate the effects of smoking cigarette or shisha tobacco on semen parameters in men with subfertility. METHODS: This was a prospective study of 100 patients with subfertility. There were 50 smokers with mean (SD) age of 37.1 (8.3) years and 50 nonsmokers with a mean age of 39.5 (9.0) years. The outcome measures were sperm abnormal forms (%), sperm count (M/mL), semen volume (mL), sperm motility (%), duration of infertility, and type, amount, and duration of smoking. Group differences (smoker vs nonsmoker and cigarette vs shisha) in semen volume and sperm parameters were analyzed with t tests. Pearson correlations were calculated to determine the association between smoking index and smoking duration and the semen parameters. RESULTS: When compared with nonsmokers, the smokers had a significantly higher mean percentage of abnormal sperm forms (92.3 % vs 89.4%) (P < .01), a significantly lower mean sperm count (20.6 M/mL vs 44.9 M/mL), a significantly lower mean semen volume (2.01 mL vs 2.52 mL), and a significantly lower mean percentage of sperm motility (25.7 vs 37.9) (all with P < .01). There were no statistically significant differences in semen parameters between men smoking cigarettes or shisha. There were statistically significant negative correlations between smoking index and the percentage of sperm motility (r =-0.38; P = .006) and between smoking duration and the percentage of sperm motility (r =-0.32; P = .026). There was also a marginally significant positive correlation between smoking index and the percentage of abnormal sperm forms (r =0.28; P = .046). Correlations with other semen parameters were not significant. CONCLUSION: Results showed significant deleterious effects of tobacco smoking on semen parameters. The correlation analysis placed special emphasis on the negative impact of smoking on sperm motility. Evidence from this and other studies seems sufficient to recommend that male smokers with subfertility should stop smoking to prevent detrimental effects on semen quality.
Effects of cigarette smoking on male fertility
Turkish Journal of Medical Sciences, 2012
, from January 2010 to May 2010. The subjects were infertile males married for more than 1 year, and they were selected randomly. The subjects were thoroughly interviewed and were selected according to inclusion criteria. History about cigarette smoking and its duration was obtained and was recorded in the questionnaire form. Results of the semen examinations were collected from the laboratory. Subjects were divided into different groups as nonsmokers and smokers. Smokers were further grouped as light, moderate, and heavy smokers. Sperm motility and morphology were taken as parameters for semen analysis. Results: It was found that 33.3% of nonsmokers showed below 5% sperm motility and 25.9% showed below 3% normal sperm morphology. Meanwhile, 66.7% of smokers showed below 5% sperm motility, and 74.1% showed below 3% normal sperm morphology. Among the 3 groups of smokers, sperm motility below 5% was present in 18.8% of light smokers, 31.2% of moderate smokers, and 50% of heavy smokers. Regarding morphology of sperm, less than 3% of normal sperm cells were present in 25% of light, 35% of moderate, and 40% of heavy smokers. Conclusion: It is concluded that cigarette smoking can affect male fertility by decreasing the sperm motility and percentage of normal sperm cells. These abnormalities are also related to the amount of cigarettes smoked per day.
The effect of cigarette smoking on the semen parameters of infertile men
Gynecological Endocrinology, 2020
Introduction: 36.9% of men worldwide use tobacco. Previous studies suggest a negative effect of cigarette smoking on semen quality, but the results are contradictory. We have studied the effects of smoking on the semen characteristics such as sperm concentration, semen volume, sperm motility, sperm vitality and sperm morphology in a large group of infertile men. Methods: This retrospective study was conducted on a total of 5146 infertile men with at least one year of idiopathic infertility, who admitted to the Centre for Reproductive medicine (CRG) at the Brussels University Hospital, Belgium between 2010 and 2017. The smokers were classified as mild (1-10 cigarettes/d), moderate (11-20 cigarettes/d) or heavy smokers (> 20 cigarettes/d). Semen analysis was performed for all patients. Statistical analysis was performed using the R software package and t-test or Mann-Whitney U tests were used, group comparisons were performed using ANOVA, ANCOVA or Kruskal-Wallis tests as appropriate. A p-value <0.05 was considered as statistically significant. Results: Comparing the semen parameters in the two global groups showed that smoking had a significant decrease in semen volume (p¼0.04074) and sperm concentration (p¼0.029). ANOVA testing on the different smoking groups versus non-smoking group showed a significant decrease in sperm concentration (p¼0.0364). After adjusting for the confounders, age and testosterone, ANCOVA testing showed significant effect on the sperm concentration (p¼0.03871) in smokers versus non-smokers. No significant correlation was detected between the other semen characteristics. Conclusion: We concluded that smoking had a significant and independent effect on the sperm concentration in a semen analysis. Other parameters, like semen volume, sperm motility, sperm vitality and sperm morphology were not influenced by smoking.
Journal of Drug Delivery and Therapeutics, 2020
Background : Cigarette smoking has negative effects on male fertility. Toxins from tobacco smoking can potentially affect sperm development and function, with a negative effect on semen parameters. In fact, the components of cigarette smoke pass through the blood-testis barrier and thus induce an alteration of sperm parameters and nucleus quality of the spermatozoa. The aim is to determine a diffence between tobbaco and no tobbaco patient and semen parameters. This article aimed to assess the relationship between smoking and male infertility. Subject and Methods : this is retrospective study focused on the effects of smoking on semen analyses. 377 men (165 non-smokers, 212 smokers) with infertility for at least 1 year were evaluated between Mars and November 2018, in center of algiers (capital of Algeria). Sperm characteristics (concentration, motility, morphology, and volume) were detemined. Results: Sperm concentration, percentage motility and morphology were significantly lo...
PubMed, 2005
In this prospective study we investigated different semen parameters of infertile smokers with a history of cigarette smoking. 27 infertile men who smoked cigarettes, 79 infertile men who were nonsmokers and 82 healthy nonsmoking donors were evaluated. Smokers had significantly less spermatozoa with motility grade B (9.37% versus 11.9%, p<0.05), decreased results of hypoosmotic swelling test (46.39% versus 52.11%, p<0.05) than nonsmokers infertile men. The concentration of leukocytes in semen was significantly higher in smokers (0.26 mln/ml versus 0.11 mln/ml, p>0.05), which can also suggests oxidative imbalance in the ejaculates of these men. No differences were found in the assessment of sperm concentration, motility grade A, C, D, percentage normal forms and different sperm defects, induced acrosomal reaction and acidic aniline blue staining test between these two groups (p>0.05). Our data demonstrate that cigarette smoking alters semen quality which could worsen fertilizing capability in infertile men.
Kirkuk Journal of Medical Sciences, 2016
Background: Cigarette smoking is a broadly recognized health hazard and a major cause of mortality but still people continue to smoke cigarettes on a regular basis. Tobacco has numerous carcinogens and mutagens which have deleterious effects on human beings. Effect of carcinogens has been observed to be more on rapidly dividing cells which include germ cells. The maximum prevalence of smoking is observed in young adult males in the reproductive period Aims and objectives: To compare different seminal fluid parameters among smoker and non-smoke, to know the effect of cigarette smoking on sperm counts, motility and morphology, and the difference in seminal fluid variables between smokers and non – smokers. Patients and Methods: The case control study performed from May 2015 to December 2015 carried in laboratory of Rizgary Teaching Hospital in Erbil city and a questionnaire prepared for each case. Only patients with primary infertility, who were either smokers or strict non-smokers, w...