Captopril does not scavenge superoxide: Captopril prevents O2⨪ production by chelating copper (original) (raw)

Evaluation of the ability of the angiotensin-converting enzyme inhibitor captopril to scavenge reactive oxygen species

Rubens Cecchini

1991

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Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor

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Biochemical and Biophysical Research Communications, 1989

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A Study of the Antioxidant Effects of Iranian Captopril on Patients with Hypertension and Heart Failure

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2010

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Captopril: a free radical scavenger

James Mclay

British Journal of Clinical Pharmacology, 1989

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Drugs and inhibitors in the control of free radical induced damage

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Journal of Molecular and Cellular Cardiology, 1988

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The Role of Antioxidant Drugs in Oxidative Injury of Cardiovascular Tissue

Jay Kramer

1999

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Influence of ACE inhibitors on free radicals and reperfusion injury: pharmacological curiosity or therapeutic hope?

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British Journal of Clinical Pharmacology, 1991

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Captopril, an ACE inhibitor, for optimizing reperfusion after acute myocardial infarction

Dipak Das

The Annals of Thoracic Surgery, 1991

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Protective effects of sulfhydryl-containing angiotensin converting enzyme inhibitors against free radical injury in endothelial cells

William Weglicki

Biochemical Pharmacology, 1990

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Can angiotensin-converting enzyme inhibitors interfere with the free radicals? Measurement of antioxidant capacity using DPPH radical reduction examined by UV-VIS method

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Na+/H+exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action

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Journal of Applied Physiology, 2008

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Free radical scavenging properties of ?-adrenoceptor blockers are not relevant for cardioprotection in isolated rabbit hearts

Alexis Rump

Naunyn Schmied Arch Pharmacol, 1993

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Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action.

Guillermo Schinella

Journal of Applied Physiology, 2008

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Possible mechanism of captopril induced endothelium-dependent relaxation in isolated rabbit aorta

Manjeet Singh

Molecular and Cellular Biochemistry, 1998

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Captopril ameliorates myocardial and hematological toxicities induced by adriamycin

Othman Shabanah

IUBMB Life, 1998

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Impact of captopril on cardiac mitochondrial function in an in-vivo animal model of atherosclerosis

Zvezdana Kojic

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Comparison of inhibitors of superoxide generation in vascular smooth muscle cells

Chris Wilcox

British Journal of Pharmacology, 2009

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Effect of captopril on prostacyclin and nitric oxide formation in healthy human subjects: Interaction with low dose acetylsalicylic acid

Dimitrios Tsikas

British Journal of Clinical Pharmacology, 2003

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Captopril inhibits the oxidative modification of apolipoprotein B-100 caused by myeloperoxydase in a comparative in vitro assay of angiotensin converting enzyme inhibitors

Pierre Van Antwerpen

European journal of pharmacology, 2006

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Evidence for norepinephrine cardiotoxicity mediated by superoxide anion radicals in isolated rabbit hearts

Alexis Rump

Naunyn-Schmiedeberg's Archives of Pharmacology, 1994

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Superoxide dismutase and glutathione peroxidase activities are increased by enalapril and captopril in mouse liver

Leon Ferder

FEBS Letters, 1995

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Effect of antihypertensive agents - captopril and nifedipine - on the functional properties of rat heart mitochondria

Iweta Waczulíková

Iranian journal of basic medical sciences, 2016

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Effects of a novel ACE inhibitor, 3-(3-thienyl)-L-alanyl-ornithyl-proline, on endothelial vasodilation and hepatotoxicity in L-NAME-induced hypertensive rats

Mahesh Kumar Seth

Drug Design Development and Therapy, 2016

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Pharmacodynamic interaction of garlic with captopril in ischemia-reperfusion induced myocardial damage in rats

Syed Mohammed Basheeruddin Asdaq

2008

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PBN spin trapping of free radicals in the reperfusion-injured heart. Limitations for pharmacological investigations

Norbert Vrbjar

Molecular and Cellular Biochemistry, 1998

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Effects of Captopril on the Renin Angiotensin System, Oxidative Stress, and Endothelin in Normal and Hypertensive Rats

Stanley Stead

Hypertension, 2005

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