Stimulation of transient versus sustained ERK1/2 phosphorylation by relative chitinase-like proteins CHI3L1 and CHI3L2 correlates with different kinase localization and biological outcome
Anton Iershov
Biopolymers and Cell, 2011
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Gene Encoding Chitinase 3-Like 1 Protein (CHI3L1) is a Putative Oncogene
Olena Balynska, Anton Iershov
International journal of biomedical science : IJBS, 2011
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Characterization of new cell line stably expressing CHI3L1 oncogene
Olena Balynska
Biopolymers and Cell, 2011
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Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma
Jürgen Beck
Cancers
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New insights into the role of the CHI3L2 protein in invasive ductal breast carcinoma: the CHI3L1 protein has a different role
Agnieszka Rusak
Research Square (Research Square), 2024
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CHI3L1 Inhibits Expression of NIS by Activating MEK/ERK1/2 Signal Pathway in Thyroid Cancer
dong duan
2021
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Role of chitinase-like proteins in cancer
Julia Kzhyshkowska
Biological Chemistry, 2016
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Chitinase 3-like-1 (CHI3L1) in the Pathogenesis of Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer
Jack a. Elias
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Chitinase-like proteins promoting tumorigenesis through disruption of cell polarity via enlarged endosomal vesicles
Sarah Herbrich
bioRxiv (Cold Spring Harbor Laboratory), 2022
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CHI3L1 promotes tumor progression by activating TGF-β signaling pathway in hepatocellular carcinoma
Biaoyang Lin
Scientific reports, 2018
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A Ligand-inducible Epidermal Growth Factor Receptor/Anaplastic Lymphoma Kinase Chimera Promotes Mitogenesis and Transforming Properties in 3T3 Cells
Francesca Fazioli
Journal of Biological Chemistry, 2002
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CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors
Stephania Libreros
Immunologic Research, 2013
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No association of (−131C→G) variant of CHI3L1 gene with risk of glioblastoma and prognosis
Anton Iershov
Journal of Neuro-oncology, 2009
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High CHI3L1 expression is associated with glioma patient survival
Paulina Vaitkienė, Giedrius Steponaitis
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Chitinase-like protein promotes tumorigenesis through disruption of cell polarity via enlarged vesicles
Sarah Herbrich
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The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways
Chantal White
Biochemical Journal, 2002
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From reverse transcription to human brain tumors
Olena Balynska, Stanislav Avdieiev
Biopolymers and Cell, 2013
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RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis
Jack a. Elias
Scientific Reports, 2016
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Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor
Tuyết Nga Nguyễn
Journal of Biological Chemistry, 1993
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In vivo Target Modulation and Biological Activity of CHIR-258, a Multitargeted Growth Factor Receptor Kinase Inhibitor, in Colon Cancer Models
Lara Nordahl, Arnold Gelb
Clinical Cancer Research, 2005
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Epidermal growth factor stimulates translocation of the class II phosphoinositide 3-kinase PI3K-C2β to the nucleus
Dora Višnjić
Biochemical Journal, 2009
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Overexpression of CHI3L1 is associated with chemoresistance and poor outcome of epithelial ovarian carcinoma
Wen-fang Cheng
Oncotarget, 2015
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Nerve and Epidermal Growth Factor Induce Protein Synthesis and eIF2B Activation in PC12 Cells
Miranda Kleijn, Adri Thomas
Journal of Biological Chemistry, 1998
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Translocation of cdk2 to the Nucleus during G1-Phase in PDGF-Stimulated Human Fibroblasts
Raimund Wieser
Experimental Cell Research, 1997
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Overexpression of chitinase like protein YKL-40 in leukemia patients
Saksham Yadav
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Human Chitinases and Chitinase-Like Proteins as Indicators for Inflammation and Cancer
Julia Kzhyshkowska
Biomarker Insights, 2007
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In vivo Target Modulation and Biological Activity of CHIR-258, a Multitargeted Growth Factor Receptor Kinase Inhibitor, in Colon Cancer Models
Arnold Gelb
Clinical Cancer Research, 2005
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Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye
Thomas Baranski
Proceedings of the National Academy of Sciences, 2007
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Involvement of phosphatidylinositol 3-kinase in nuclear translocation of protein kinase C ζ induced by C2-ceramide in rat hepatocytes
Edgardo Lara
Febs Letters, 2002
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Chitinase 3-like 1 is neurotoxic in primary cultured neurons
Clara Blanch
Scientific Reports, 2020
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Protein Kinase Ce Plays a Role in Neurite Outgrowth in Response to Epidermal Growth Factor and Nerve Growth Factor in PC12 Cells
Philip Lazarovici
1999
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β2-Chimaerin in Cancer Signaling: Connecting Cell Adhesion and MAP Kinase Activation
Thomas Baranski
Cell Cycle, 2007
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NGF induces transient but not sustained activation of ERK in PC12 mutant cells incapable of differentiating
David Gurwitz
Journal of Cellular Biochemistry, 1998
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Protein Kinase Ca and Protein Kinase Cd Play Opposite Roles in the Proliferation and Apoptosis of Glioma Cells1
Ilana Kronfeld, Ely Ashkenazi
2001
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Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism
Jack a. Elias
2009
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