β-Secretase-1: In Silico Drug Reposition for Alzheimer’s Disease (original) (raw)

Factors Influencing the Potency of Alzheimer Inhibitors: Computational and Docking Studies

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American journal of Alzheimer's disease and other dementias, 2018

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Structure-Based Design of β‑Site APP Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer's Disease

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Scaffold Morphing and In Silico Design of Potential BACE-1 (β-Secretase) Inhibitors: A Hope for a Newer Dawn in Anti-Alzheimer Therapeutics

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Romano Silvestri

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Emerging Alzheimer’s disease therapies: inhibition of β-secretase

Martin Citron

Neurobiology of Aging, 2002

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Determination of Potential Multi-Target Inhibitors of Alzheimer’s Disease in Silico

Glendalyn Boothe

2019

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Chronicles of Pharmaceutical Science Research Article Evaluation and Optimisation of in Silicon Designed B-Secretase Modulators for the Treatment of Alzheimer's Disease

Dr. Claire Shoemake

2017

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In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer's Disease Using Borassus flabellifer Linn

Samsoon Maharifa

Applied Biochemistry and Biotechnology, 2022

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Structure guided P1′ modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer’s disease

Michael Bartberger

Bioorganic & Medicinal Chemistry Letters, 2012

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Identifying Potential Bace-1 Enzyme Inhibitors /Lead Small Molecules: Relevance to Alzheimer's Diseases

Deepak Ganesh

Zenodo (CERN European Organization for Nuclear Research), 2022

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β-Secretase inhibition for the treatment of Alzheimer's disease – promise and challenge

Martin Citron

Trends in Pharmacological Sciences, 2004

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In silico molecular studies of natural compounds as possible anti-Alzheimer’s agents: ligand-based design

IBRAHIM MOMOH

Network Modeling Analysis in Health Informatics and Bioinformatics, 2020

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Ensemble-Docking Approach on BACE-1: Pharmacophore Perception and Guidelines for Drug Design

Sandro Cosconati

ChemMedChem, 2007

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Discovery of Novel Acetylcholinesterase Inhibitor Implication for the Design of New Anti-Alzheimer Agents

Amir Zeb

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Targeting BACE 1(Beta secretase) through Polyphenolic compounds -A computational insilicoapproach with emphasis on binding site analysis

Sumathy Arunachalam

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Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo

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In-Silico Drug Identification in the Treatment of Neurodegenerative Disease; Alzheimer

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?-secretase as a target for the treatment of Alzheimer's disease

Martin Citron

Journal of Neuroscience Research, 2002

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Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease

B. Imbimbo

Expert Opinion on Drug Discovery, 2012

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Halogen‑directed drug design for Alzheimer's disease: a combined density functional and molecular docking study

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β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

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Molecular modeling, docking and ADMET studies applied to the design of a novel hybrid for treatment of Alzheimer's disease

Ivone Carvalho

Journal of Molecular Graphics and Modelling, 2006

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Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality

Gabriela Barreiro

Journal of medicinal chemistry, 2016

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Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors

Michael Malamas

Bioorganic & Medicinal Chemistry Letters, 2010

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Rational drug repurposing for alzheimer’s treatment using in-silico ligand and structure-based approaches

Ravindra Wavhale

Brazilian Journal of Pharmaceutical Sciences, 2024

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New theoretical model for the study of new β-secretase inhibitors

Jan-carlo Díaz

Proceedings of MOL2NET, International Conference on Multidisciplinary Sciences, 2015

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Structure-based design and synthesis of macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors

Ulf Neumann

Bioorganic & Medicinal Chemistry Letters, 2009

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Design of novel amyloid β aggregation inhibitors using QSAR, pharmacophore modeling, molecular docking and ADME prediction

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Current and novel therapeutic molecules and targets in Alzheimer’s disease

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Recent insight into BACE1 as a potential target for treatment of Alzheimer's disease

Samia Mostafa

2021

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