β-Secretase-1: In Silico Drug Reposition for Alzheimer’s Disease (original) (raw)
Factors Influencing the Potency of Alzheimer Inhibitors: Computational and Docking Studies
Prof.Mohamed Awad
American journal of Alzheimer's disease and other dementias, 2018
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Beta-secretase as a target for Alzheimer’s disease drug discovery: an overview of in vitro methods for characterization of inhibitors
Vincenza Andrisano
Analytical and Bioanalytical Chemistry, 2011
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Structure-Based Design of β‑Site APP Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer's Disease
Shankar Venkatraman
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Scaffold Morphing and In Silico Design of Potential BACE-1 (β-Secretase) Inhibitors: A Hope for a Newer Dawn in Anti-Alzheimer Therapeutics
krishna kumar mishra
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Boom in the development of non-peptidic β-secretase (BACE1) inhibitors for the treatment of Alzheimer's disease
Romano Silvestri
Medicinal Research Reviews, 2009
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Emerging Alzheimer’s disease therapies: inhibition of β-secretase
Martin Citron
Neurobiology of Aging, 2002
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Determination of Potential Multi-Target Inhibitors of Alzheimer’s Disease in Silico
Glendalyn Boothe
2019
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Chronicles of Pharmaceutical Science Research Article Evaluation and Optimisation of in Silicon Designed B-Secretase Modulators for the Treatment of Alzheimer's Disease
Dr. Claire Shoemake
2017
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In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer's Disease Using Borassus flabellifer Linn
Samsoon Maharifa
Applied Biochemistry and Biotechnology, 2022
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Structure guided P1′ modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer’s disease
Michael Bartberger
Bioorganic & Medicinal Chemistry Letters, 2012
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Identifying Potential Bace-1 Enzyme Inhibitors /Lead Small Molecules: Relevance to Alzheimer's Diseases
Deepak Ganesh
Zenodo (CERN European Organization for Nuclear Research), 2022
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β-Secretase inhibition for the treatment of Alzheimer's disease – promise and challenge
Martin Citron
Trends in Pharmacological Sciences, 2004
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In silico molecular studies of natural compounds as possible anti-Alzheimer’s agents: ligand-based design
IBRAHIM MOMOH
Network Modeling Analysis in Health Informatics and Bioinformatics, 2020
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Ensemble-Docking Approach on BACE-1: Pharmacophore Perception and Guidelines for Drug Design
Sandro Cosconati
ChemMedChem, 2007
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Discovery of Novel Acetylcholinesterase Inhibitor Implication for the Design of New Anti-Alzheimer Agents
Amir Zeb
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Targeting BACE 1(Beta secretase) through Polyphenolic compounds -A computational insilicoapproach with emphasis on binding site analysis
Sumathy Arunachalam
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Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo
Amiram Goldblum
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In-Silico Drug Identification in the Treatment of Neurodegenerative Disease; Alzheimer
Dr. PRASHANT K U M A R SINGH
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?-secretase as a target for the treatment of Alzheimer's disease
Martin Citron
Journal of Neuroscience Research, 2002
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Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease
B. Imbimbo
Expert Opinion on Drug Discovery, 2012
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Halogen‑directed drug design for Alzheimer's disease: a combined density functional and molecular docking study
Mohammad Mahfuz Ali Khan Shawan
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β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease
alessandra bergadano
Journal of Medicinal Chemistry, 2013
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Molecular modeling, docking and ADMET studies applied to the design of a novel hybrid for treatment of Alzheimer's disease
Ivone Carvalho
Journal of Molecular Graphics and Modelling, 2006
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Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality
Gabriela Barreiro
Journal of medicinal chemistry, 2016
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Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors
Michael Malamas
Bioorganic & Medicinal Chemistry Letters, 2010
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Rational drug repurposing for alzheimer’s treatment using in-silico ligand and structure-based approaches
Ravindra Wavhale
Brazilian Journal of Pharmaceutical Sciences, 2024
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New theoretical model for the study of new β-secretase inhibitors
Jan-carlo Díaz
Proceedings of MOL2NET, International Conference on Multidisciplinary Sciences, 2015
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Structure-based design and synthesis of macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors
Ulf Neumann
Bioorganic & Medicinal Chemistry Letters, 2009
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Design of novel amyloid β aggregation inhibitors using QSAR, pharmacophore modeling, molecular docking and ADME prediction
Aswathy Lilly
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Current and novel therapeutic molecules and targets in Alzheimer’s disease
Awanish Kumar, Ashwini Kumar, Timir Tripathi
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Recent insight into BACE1 as a potential target for treatment of Alzheimer's disease
Samia Mostafa
2021
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