Antimicrobial screening and phytochemical analysis of the resin part of Acacia catechu (original) (raw)
Related papers
In Vitro Antimicrobial Activity of Acacia catechu and Its Phytochemical Analysis
Indian Journal of Microbiology, 2010
Acacia catechu, commonly known as catechu, cachou and black cutch is an important medicinal plant and an economically important forest tree. The methanolic extract of this plant was found to have antimicrobial activities against six species of pathogenic and non-pathogenic microorganisms: Bacillus subtilis, Staphylococcus aureus, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. The maximum zone of inhibition (20 mm) was found to be exhibited against S. aureus. For this organism the minimum bactericidal concentration (MBC) of the crude extract was 1,000 μg/ml. The extract was found to be equally effective against gram positive and gram negative bacteria. The antimicrobial activity of the extract was found to be decreased during purification. The chemical constituents of organic plant extracts were separated by thin layer chromatography (TLC) and the plant extracts were purified by column chromatography and were further identified by Gas chromatography–mass selection (GC–MS) analysis. The composition of A. catechu extract had shown major components of terpene i.e. camphor (76.40%) and phytol (27.56%) along with other terpenes in minor amounts which are related with their high antibacterial and antifungal properties.
Plants
With the advent of pandemics and infectious diseases, numerous research activities on natural products have been carried out to combat them. Researchers are investigating natural products for the treatment and/or management of various infectious diseases and/or disorders. Acacia catechu (L.f.) Willd. belongs to the family Fabaceae (subfamily Mimosoideae) known as Khair or Cutch tree, possesses diverse pharmacological actions, and has been widely used in Asia and different parts of the world. The purpose of the present study is to highlight the phytochemical profile of different parts of A. catechu, the different biological activities of A. catechu extract, and the utilization of A. catechu as food and beverage. The present work constitutes a review of A. catechu; we performed searches (books, Google, Google Scholar, and Scopus publications) to compile the work/investigations made on A. catechu to the present. From our survey, it was concluded that the main phytochemicals compounds i...
AMAZING ANTIMICROBIAL AND WOUND HEALING POTENTIAL OF ACACIA CATECHU BARK EXTRACTS-A REVIEW
Asian Journal of Pharmaceutical and Clinical Research, 2021
Plants are not only the source of food, oxygen, and shelter, but the same are also a potential foundation of medicines. Many natural and plant-derived antimicrobial and wound healing compounds have been recognized. In the present review, we have studied the main bioactive components of Acacia catechu with their medicinal roles. Most of these bioactive components are secondary metabolites which are produced by plants as side products of certain physiological reactions and are of no use for the plant itself. These components have been reported for their medicinal properties. In this review, we have mentioned some antibacterial, antifungal, and wound healing properties of A. catechu with its known bioactive components. The aim of this review article is, to enlist the possible potent bioactive components of the plant, against pathogenic microbes that can replace the use of chemicals and synthetic antibiotics for the treatment of skin infections and other diseases.
Qualitative and Quantitative Phytochemical Analysis of Acacia Catechu Willd
International Journal of Scientific Research in Science and Technology, 2020
Acacia catechu willd has a great importance due to its medicinal properties. It is a historical plant; widely used in traditional medicine especially in Asia. Modern technology has made easy to study pharmacological properties of traditional medicine so great interests have been developed in historical traditional plants. There is a great use of Acacia catechu in dermatology and sore throat. Now a days antimycotic, hypoglycemic activity has also been reported. Phenols or polyphenols are the natural chemicals which are found in Acacia catechu. Phenolic compounds have similar basic structural chemistry as that of aromatic compounds and they contain a basic phenolic ring. They have an astringent effect and are widely used in tanning of lathers. They are also used in cancer treatment, dermatological disorders and possess anti-microbial activity. One of the most important feature of these compounds is their anti-oxidant effect. Due to the presence of these compounds in Acacia catechu wil...
Comprehensive Dossier on Ayurvedic Medicinal plant Acacia catechu Willd. : A Review
2017
The plant Acacia catechu, commonly known as the cutch tree is a tropically abundant plant which is widely used in Indian subcontinent with some presence in Central Asia and in China. The species has lent its name to important catechins, catechols. The most used part of this plant is stem or heartwood as water extract. Some pharmacological demonstrations have also been done with ethyl acetate extract. Leaves of the plant found some primary applications in biological actions. Presence of several polyphenolic compounds like tannins, flavonoids are responsible for many biological activities. The ethno pharmacological values of the plant make it a potent therapeutic and cosmetic agent. In the present review, comprehensive information on pharmacognostic evaluation, botanical aspects, therapeutic values, modern pharmacological activities and chemical constituents along with their 1 H NMR data are provided to explore the potential and to advance research.
International Journal of Herbal Medicine, 2018
Acacia catechu is a deciduous tree and reported to possess therapeutic properties. In the present study fifty percent hydromethanolic extract of leaves of Acacia catechu (ACE) was prepared and analyzed for presence of various phytoconstituents in ACE employing different biochemical qualitative tests and GCMS analysis. It was further explored for its antioxidative potential through hydrogen peroxide scavenging assay. Biochemical tests confirmed presence of various phytochemicals viz., resins, tannins, Saponins, flavonoids, alkaloids, glycosides, etc. GC-MS analysis showed presence of four compounds when compared with NIST and WELLY library. Acacia catechu (A. catechu) showed presence of Caprylic acid methyl ester (19.77%), Lauric acid methyl ester (27.42%), 2-Ethyl-3-methyl-1-butene (42.09%) and Myristic acid methyl ester (10.72%), etc. The present study indicated anti-oxidative property of ACE. The percent H2O2 scavenging activity of ACE was found to be 33.40%. Thus it could be infe...
Pharmacognostical studies on Acacia catechu willd and identification of antioxidant principles
International Journal of …, 2011
Acacia catechu Willd. (Fam-Mimosaceae; Eng-Cutch tree; Mal-Karingali; Sans-Khadira) is an important medicinal plant used in Ayurveda for so many diseases and commonly for mother and child healthcare. The plant is a moderate sized, deciduous tree up to 3m high and distributed throughout the Sub-Himalayan tract of Punjab to Assam ascending to 1200m. In the present paper, a detailed pharmacognostic study on the heartwood of Acacia catechu based on its physicochemical, macroscopic, and microscopic and biochemical features was carried out. The drug is used as a medicine for several common ailments like skin diseases, ulcers, diabetes etc. These medicinal properties may be due to their antioxidant properties. Hence a preliminary study on the antioxidant activity of the alcohol extract was carried out by evaluating the free radical scavenging activity by the method of DPPH radical scavenging assay. The extract gave very good radical scavenging activity comparable with that of ascorbic acid which was used as the standard. Since flavonoids are reported to be strong antioxidants, an attempt was also made to estimate the flavonoids present in the alcoholic extract of Acacia catechu. The detection and estimation of flavonoids were carried out by HPLC method using Binary gradient UFLC system equipped with C18 column and UV/Vis detector. These studies on Acacia catechu are being reported for the first time.
Advances in Microbiology, 2016
The ethanol, chloroform and acetone extracts of five species from Acacia (Acacia albidia stems, Acacia mellifera aerial parts, Acacia nubica aerial parts, Acacia seyal var. seyal stems and Acacia tortilis aerial parts) were investigated for their antimicrobial activity against two standard bacterial strains of Gram +ve bacteria (Staphylococcus aureus (ATCC 25923)), Gram −ve bacteria (Pseudomonas aeruginosa (ATCC 27853)) and standard fungi Candida albicans (ATCC 90028) using the agar-plate well diffusion method. The chloroform extract was inactive compared to ethanol and acetone extracts. But ethanol extracts showed the maximum antimicrobial activity against the test organism. Amongst the plant species screened, ethanol extract of Acacia seyal stems showed maximum inhibitory activity (38 mm) and (37 mm) against Staphylococcus aureus and Candida albicans, respectively. The ethanol, chloroform and acetone extracts of Acacia mellifera (aerial parts) did not show any activity against the test organisms. Cholorophorm and acetone extracts via DPPH, the radical scavenging activities were found to be 91 ± 0.03, 88 ± 0.01 and 85 ± 0.04, respectively. The results of phytochemical screening showed that all extracts of studied plant contain flavonoids, saponins, terpenoids, steroids, alkaloids, phenols and tannins. H. B. Abdllha et al.
This study was undertaken to check for the presence of phytochemicals constituents, antioxidant and antimicrobial properties of ethyl acetate and acetone extract of acacia albida stem bark at various concentration (25mg/ml, 50mg/ml, 75mg/ml and 100mg/ml). The antioxidant property was determined using DPPH scavenging activity and phosphomolybdenum assays. The antimicrobial activity was also determined using modified Kirbybaur method. DPPH percentage inhibition increases as the concentration increase, while phosphomolybdenum percentage inhibition decreases as the concentration increase. Both extracts of Acacia albida have antimicrobial activity with ethylacetate extract showing higher activity against test bacteria Bacillus subtilis whereas acetone extract shows higher activity against Salmonella typhi which increases as the concentration increase.