Subcellular localization and sorting of MHC class II molecules (original) (raw)

Major histocompatibility complex class II-restricted presentation of secreted and endoplasmic reticulum resident antigens requires the invariant chains and is sensitive to lysosomotropic agents

Patrick Bertolino

European Journal of Immunology, 1993

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Intracellular organelles involved in antigen processing and the binding of peptides to class II MHC molecules

Clifford Harding

Seminars in Immunology, 1995

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The invariant chain induces compact forms of class II molecules localized in late endosomal compartments

Jean Davoust

European Journal of Immunology, 1993

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The function of the invariant chain in antigen presentation by MHC class II molecules

jose joel castañeda moreno

Immunology Today, 1990

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Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum

Sebastian Joyce

Journal of Molecular Biology, 1997

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The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail

Bernhard Dobberstein

Journal of Cell Science, 1993

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Antigen Loading of MHC Class I Molecules in the Endocytic Tract

Cornelis Melief

Traffic, 2001

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Class I molecules retained in the endoplasmic reticulum bind antigenic peptides

Igor Bacik

The Journal of experimental medicine, 1993

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MHC Class II-Associated Invariant Chain-Induced Enlarged Endosomal Structures: A Morphological Study

Oddmund Bakke

Experimental Cell Research, 1997

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Different endocytic compartments are involved in the tight association of class II molecules with processed hen egg lysozyme and ribonuclease A in B cells

Philippe Chavrier

Journal of Cell Science, 1995

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Complexes the Formation of Peptide:Class II MHC Antigen-Processing Organelles That Mediate Phagosomes Are Fully Competent

Clifford Harding

1999

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Mouse B lymphocyte specific endocytosis and recycling of MHC class II molecules

Jean Davoust

The EMBO Journal, 1990

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Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH

P. Chefalo

The Journal of Immunology, 2001

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Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner

Ekkehard Weber

Journal of Leukocyte Biology, 2003

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Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures

Richard Wubbolts

The Journal of Cell Biology, 1994

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MHC Class II Transport from Lysosomal Compartments to the Cell Surface Is Determined by Stable Peptide Binding, But Not by the Cytosolic Domains of the a- and b-Chains1

Clotilde Théry

2000

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Processing and Presentation of Endocytically Acquired Protein Antigens by MHC Class II and Class I Molecules

Paola Romagnoli

Immunological Reviews, 1996

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Introduction of a Glycosylation Site into a Secreted Protein Provides Evidence for an Alternative Antigen Processing Pathway: Transport of Precursors of Major Histocompatability Complex Class I-Restricted Peptides from the Endoplasmic Reticulum to the Cytosol

Weisan Chen

Journal of Experimental Medicine, 1997

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Phagosomes Are Fully Competent Antigen-Processing Organelles That Mediate the Formation of Peptide:Class II MHC Complexes

Clifford Harding

The Journal of Immunology, 1999

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Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing

Clifford Harding

Proceedings of the National Academy of Sciences, 1990

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Lamp-2a Facilitates MHC Class II Presentation of Cytoplasmic Antigens

Janice Blum

Immunity, 2005

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Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes

W. Stoorvogel

Journal of Biological Chemistry, 1998

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The pathway for MHCII-mediated presentation of endogenous proteins involves peptide transport to the endo-lysosomal compartment

Deepa Rajagopal

Journal of Cell Science, 2004

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Endosomal trafficking of open Major Histocompatibility Class I conformers—Implications for presentation of endocytosed antigens

Pero Lučin

Molecular Immunology, 2013

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Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment

Colin Hopkins

The Journal of cell biology, 1994

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Trafficking of spontaneously endocytosed MHC proteins

I. Chiu, Jack Strominger

Proceedings of the National Academy of Sciences, 1999

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An LI, ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization

Oddmund Bakke

Journal of Cell Science

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Endocytosis mechanisms and the cell biology of antigen presentation

Christian Kurts

Current Opinion in Immunology, 2008

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How MHC class II molecules reach the endocytic pathway

Philippe Benaroch

The EMBO Journal, 1995

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An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization

Oddmund Bakke

Journal of Cell Science, 1994

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Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling

Oddmund Bakke

European Journal of Immunology, 1994

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Endocytosis and dissociation of class I MHC molecules labeled with fluorescent beta-2 microglobulin

Jerome Hochman

The Journal of Immunology

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