An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization
Oddmund Bakke
Journal of Cell Science, 1994
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The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail
Bernhard Dobberstein
Journal of Cell Science, 1993
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MHC Class II-Associated Invariant Chain-Induced Enlarged Endosomal Structures: A Morphological Study
Oddmund Bakke
Experimental Cell Research, 1997
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Structure-Activity Relationship of the Leucine-based Sorting Motifs in the Cytosolic Tail of the Major Histocompatibility Complex-associated Invariant Chain
Gabriella Saviano
Journal of Biological Chemistry, 1995
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The invariant chain induces compact forms of class II molecules localized in late endosomal compartments
Jean Davoust
European Journal of Immunology, 1993
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Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence
Lynne Arneson
The Journal of Cell Biology, 1995
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Intracellular transport and localization of major histocompatibility complex class II molecules and associated invariant chain
Oddmund Bakke
Journal of Cell Biology, 1991
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Expression of Major Histocompatibility Complex Class II Molecules in HeLa Cells Promotes the Recruitment of AP-1 Golgi-specific Assembly Proteins on Golgi Membranes
Bruno Goud
Journal of Biological Chemistry, 1996
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Subcellular localization and sorting of MHC class II molecules
Jean Salamero
Biology of the Cell, 1991
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Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal
Lynne Arneson
Journal of Experimental Medicine, 1993
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Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments
Oddmund Bakke
Journal of Experimental Medicine, 1993
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How MHC class II molecules reach the endocytic pathway
Philippe Benaroch
The EMBO Journal, 1995
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Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum
Sebastian Joyce
Journal of Molecular Biology, 1997
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Major histocompatibility complex class II-restricted presentation of secreted and endoplasmic reticulum resident antigens requires the invariant chains and is sensitive to lysosomotropic agents
Patrick Bertolino
European Journal of Immunology, 1993
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Early endosomal rerouting of major histocompatibility class I conformers
Pero Lučin
Journal of Cellular Physiology, 2012
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Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment
Colin Hopkins
The Journal of cell biology, 1994
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The pathway for MHCII-mediated presentation of endogenous proteins involves peptide transport to the endo-lysosomal compartment
Deepa Rajagopal
Journal of Cell Science, 2004
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Ii Chain Controls the Transport of Major Histocompatibility Complex Class II Molecules to and from Lysosomes
Ira Mellman
The Journal of Cell Biology, 1997
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Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum
Isabelle Cloutier
The EMBO journal, 1996
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Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide
Frank Momburg
Journal of Experimental Medicine, 1993
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MHC II and the Endocytic Pathway: Regulation by Invariant Chain
Ole Landsverk
Scandinavian Journal of Immunology, 2009
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Endosomal trafficking of open Major Histocompatibility Class I conformers—Implications for presentation of endocytosed antigens
Pero Lučin
Molecular Immunology, 2013
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Complexes the Formation of Peptide:Class II MHC Antigen-Processing Organelles That Mediate Phagosomes Are Fully Competent
Clifford Harding
1999
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Different endocytic compartments are involved in the tight association of class II molecules with processed hen egg lysozyme and ribonuclease A in B cells
Philippe Chavrier
Journal of Cell Science, 1995
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Early endosomes are required for major histocompatiblity complex class II transport to peptide-loading compartments
G. Pehau-arnaudet
Molecular biology of the cell, 1999
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Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes
G. Raposo
Journal of Experimental Medicine, 1995
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Structural Requirements for Major Histocompatibility Complex Class II Invariant Chain Endocytosis and Lysosomal Targeting
Sunghyun KANG
Journal of Biological Chemistry, 1998
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The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy
Paola Romagnoli
Journal of Experimental Medicine, 1994
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Processing of Exogenous Antigens for Presentation by Class I MHC Molecules Involves Post-Golgi Peptide Exchange Influenced by Peptide-MHC Complex Stability and Acidic pH
P. Chefalo
The Journal of Immunology, 2001
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Related Leucine-based Cytoplasmic Targeting Signals in Invariant Chain and Major Histocompatibility Complex Class II Molecules Control Endocytic Presentation of Distinct Determinants in a Single Protein
Paola Romagnoli
2000
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MHC Class II Transport from Lysosomal Compartments to the Cell Surface Is Determined by Stable Peptide Binding, But Not by the Cytosolic Domains of the a- and b-Chains1
Clotilde Théry
2000
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Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures
Richard Wubbolts
The Journal of Cell Biology, 1994
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The leucine-based motif DDQxxLI is recognized both for internalization and basolateral sorting of invariant chain in MDCK cells
Oddmund Bakke
European Journal of Cell Biology, 1998
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Phagosomes Are Fully Competent Antigen-Processing Organelles That Mediate the Formation of Peptide:Class II MHC Complexes
Clifford Harding
The Journal of Immunology, 1999
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Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM
Christoph Driessen
The EMBO Journal, 2000
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