The emerging role of Nrf2 in dermatotoxicology (original) (raw)

Nrf2 Involvement in Chemical-Induced Skin Innate Immunity

Saadia Kerdine-römer

Frontiers in Immunology, 2019

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Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice

Matthias Schäfer

EMBO Molecular Medicine, 2014

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Transcriptional Upregulation of Nrf2-Dependent Phase II Detoxification Genes in the Involved Epidermis of Vitiligo Vulgaris

Rajni Rani

Journal of Investigative …, 2010

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Redox activation of Nrf2 & NF-κB: A double end sword?

Mabel Buelna

Cellular Signalling, 2013

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Nrf2 links epidermal barrier function with antioxidant defense

Daniel Hohl

EMBO Molecular Medicine, 2012

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REVIEW OF NRF2-REGULATED GENES INDUCED IN RESPONSE TO ANTIOXIDANTS

editor ijmrhs

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The dual role of Nrf2 in melanoma: a systematic review

Nasim Dana

BMC Molecular and Cell Biology

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Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome

Matthias Schäfer

Disease Models & Mechanisms, 2020

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Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

Courtney Woods

Environmental health perspectives, 2011

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Attenuation of UVB-Induced Sunburn Reaction and Oxidative DNA Damage with no Alterations in UVB-Induced Skin Carcinogenesis in Nrf2 Gene-Deficient Mice

Yasuhiro Fujisawa

Journal of Investigative Dermatology, 2008

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Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

Joe McCord, Brooks Hybertson

Molecular Aspects of Medicine, 2011

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The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

Truyen N Nguyen

Free Radical Biology and Medicine, 2004

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Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations

Eric Haertel

Cancer research, 2015

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Nuclear factor erythroid 2-related factor gene variants and susceptibility of arsenic-related skin lesions

Lorena Orozco

Human & Experimental Toxicology, 2013

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Nrf2 Activation as a Key Event Triggered by Skin Sensitisers: The Development of the Stable KeratinoSens Reporter Gene Assay

Andreas Natsch

Alternatives to Laboratory Animals

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Induction of skin sensitization is augmented in Nrf2-deficient mice

Eric Gremmer

Archives of Toxicology, 2013

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Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered

Vỹ Ngô

International Journal of Molecular Sciences, 2021

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Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues and energy status, and pathways through which it attenuates degenerative disease

Albena Dinkova-kostova

Free radical biology & medicine, 2015

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Allergic skin inflammation induced by chemical sensitizers is controlled by the transcription factor Nrf2.

Stefan Martin, Zeina El Ali

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Nrf2 and AhR in metabolic reprogramming after contaminant exposure

Laurence HUC

Current Opinion in Toxicology, 2018

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A review of the evidence that ochratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity

Paul Jennings

Toxins, 2014

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The Nrf2Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

Ha Nguyen

Journal of Biological Chemistry, 2009

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Data from Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans

Albena Dinkova-kostova

2023

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Nrf2/Keap1 Pathway and Expression of Oxidative Stress Lesions 8-hydroxy-2'-deoxyguanosine and Nitrotyrosine in Melanoma

Ylermi Soini

Anticancer research, 2016

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Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling

R. Wu

AJP: Lung Cellular and Molecular Physiology, 2007

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

Minerva Ramos-gómez

Proceedings of the National Academy of Sciences, 2001

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Essential role of Nrf2 in protection against hydroquinone- and benzoquinone-induced cytotoxicity

Mahara Valverde

Toxicology in Vitro, 2011

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Effects of atmospheric pollutants on the Nrf2 survival pathway

Mahara Valverde

Environmental Science and Pollution Research, 2010

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