Histopathological Study of Tumor and Tumor Like Lesions of the Oral Cavity (original) (raw)
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Histopathological Interpretation of Oral Cavity Lesions: Study at a Tertiary Care Hospital
IOSR Journals , 2019
Although the oral cavity lesions constitute only a small minority of pathological conditions, they are of great significance, as they have a potential to jeopardize the health and longevity of the patient. Among the various oral cavity lesions, oral cancer is a global health problem with increasing incidence and mortality rates. In India a vast majority of oral cancers are preceded by precancerous lesions & conditions caused by the use of tobacco in various forms. The aim of the present study is to know the spectrum and patterns of various oral cavity lesions at a tertiary care hospital, Ahmedabad, Gujarat, India. This is a one year study from June 2017 to May 2018. All the oral cavity specimens received in the Department of Pathology, GCS Hospital during the study period were included for the study. Data such as age, gender, and site of the lesion was collected. Data collected was analyzed. A total of 100 cases were analyzed during the study period. Age ranged from 2 to 78 years in the study. Overall male were affected more than the female with male:female (M:F) ratio of 3.5:1. Buccal mucosa (33%) was the commonest site involved followed by tongue (28%). Neoplastic lesions accounted for 69% cases and nonneoplastic accounted for 31% cases. Among the neoplastic lesion, squamous cell carcinoma (SCC) was seen in 40% cases; verrucous carcinoma in 6% and ameloblastic carcinoma in 1% cases; and adenosquamous carcinoma 1% cases. Most of the malignant lesions were located in the buccal mucosa (16%) and tongue (15%), followed by gingiva (6%),palate & floor of mouth (4%) each, lips (2%) alveolus (1%). Histology along with a detailed clinical work-up was found to be a useful, reliable and accurate diagnostic technique for lesions of oral cavity. A variety of lesions were encountered in the study with predominance of malignant lesions. Squamous cell carcinoma was the commonest malignant lesion.
A Histopathological Study of Oral Cavity Lesions
https://www.ijhsr.org/IJHSR\_Vol.10\_Issue.3\_March2020/IJHSR\_Abstract.03.html, 2020
Background: Oral cavity is most common site for both non-neoplastic and neoplastic lesions. Most of the lesions are asymptomatic. Oral cancer is a major health problem in developing countries and hence it is important to examine precancerous lesion of oral cavity meticulously as they potentially develop into carcinomas. Objectives: To study various types of neoplastic and non-neoplastic lesions of oral cavity with reference to age, sex and site of lesion. Material and Methods: This was a prospective study carried out in a Department of Pathology, MGM medical College Kamothe, Navi Mumbai. Total 80 Cases oral cavity lesions were studied. Results: Out of 80 cases 24 (30%) were non-neoplastic and 56 (70%) were neoplastic lesions. Male predominance was seen in both the lesions. The most of the non-neoplastic lesions were seen in age group of 0-10 years and 21-30 years while neoplastic lesions were seen in 51-60 years of age group. Out of 56 Neoplastic lesions benign (12%), premalignant (29%), and malignant lesions (59%). Most common site of involvement in non-neopalstic lesion was palatine tonsils while majority of benign and premalignant lesions were seen in buccal mucosa (5% and 12% respectively). Tongue (20%) was the most common site for malignant lesions. Maximum cases of tonsillitis (14%) were seen in non-neoplastic lesions. Squamous cell carcinoma was seen in 39% of cases. Conclusion: Early detection of premalignant lesions can prevent further complication. Hence, not only clinical examination but also histopathological examination which is a gold standard for various lesions of oral cavity.
Histopathological Study of Oral Cavity Lesions
International Journal of Scientific Research, 2012
Background: Oral cavity is most common site for both non-neoplastic and neoplastic lesions. Most of the lesions are asymptomatic. Oral cancer is a major health problem in developing countries and hence it is important to examine precancerous lesion of oral cavity meticulously as they potentially develop into carcinomas. Objectives: To study various types of neoplastic and non-neoplastic lesions of oral cavity with reference to age, sex and site of lesion. Material and Methods: This was a prospective study carried out in a Department of Pathology, MGM medical College Kamothe, Navi Mumbai. Total 80 Cases oral cavity lesions were studied. Results: Out of 80 cases 24 (30%) were non-neoplastic and 56 (70%) were neoplastic lesions. Male predominance was seen in both the lesions. The most of the non-neoplastic lesions were seen in age group of 0-10 years and 21-30 years while neoplastic lesions were seen in 51-60 years of age group. Out of 56 Neoplastic lesions benign (12%), premalignant (29%), and malignant lesions (59%). Most common site of involvement in non-neopalstic lesion was palatine tonsils while majority of benign and premalignant lesions were seen in buccal mucosa (5% and 12% respectively). Tongue (20%) was the most common site for malignant lesions. Maximum cases of tonsillitis (14%) were seen in non-neoplastic lesions. Squamous cell carcinoma was seen in 39% of cases. Conclusion: Early detection of premalignant lesions can prevent further complication. Hence, not only clinical examination but also histopathological examination which is a gold standard for various lesions of oral cavity.
Histopathological Audit of Oral Epithelial Lesions
2014
The objective of the study was to see the morphological pattern and frequency of oral epithelial lesions. All oral biopsies received in the Department of Pathology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre Karachi, over a period of 5 years were reviewed and relevant special stains were performed. A total of 685 cases were reviewed. Five hundred twelve (75%) were found neoplastic and 173 (25%) were non neoplastic. Granuloma Pyogenicum was the commonest (65) non neoplastic lesions. In neoplastic lesions, 498 cases were epithelial while 14 cases were diagnosed as non-epithelial lesions. Squamous cell carcinoma was found to be commonest (412 cases) epithelial malignant neoplastic lesion. There was a single case of benign epithelial lesion(Papilloma). The epithelial precursor lesions include 75(15%) cases of hyperplasia followed by 10(2%) showing mild dysplasia. Oral malignant epithelial lesions were common in 5th decade of life in males and 4th decade in fema...
To See the Histo-Pathological Pattern of Oral Mucosal Lesions
International Journal of Medical and Biomedical Studies, 2021
Background & Method: This prospective observational study was carried out with total number of patients 60 in the Department of Otorhinolaryngology and head and neck surgery, Amaltas Institute of Medical Sciences, Dewas, M.P., w.e.f. from August 2018 to September 2020. Patient was thoroughly investigated for complete haemogram, blood sugar, blood urea, serum creatinine, bleeding & Clotting time, coagulation profile, chest x-ray for any secondary focus. Result: Out of 35 cases of clinically premalignant lesions 30 cases were positive for malignant cells on histology. 5 were suspicious for malignant cells. Out of the 25 cases of clinically malignant lesions 25 cases were positive for malignant cells on histology and nil cases of suspicious for malignancy. In this present study, on histopathology premalignant lesions was found in 8.33% and malignancy was seen 91.66% cases. On histopathological examination, squamous cell carcinoma was the most common type among all cases (78.33%). I...
Pattern of oral lesions – Cytohistopathological study in tertiary care centre
International Journal of Current Research in Medical Sciences, 2017
The prevalence and incidence of oral lesions are uncommon. Many of these lesions can be identified as specific entities on the basis of their histopathological features and are divided into epithelial, fibrous, vascular and giant cell type. Smoking, drinking alcohol and chewing tobacco products are common habits in India, which have been positively associated with oral lesions. Oral cancers account for over 30% of all cancers in India. Despite this fact, in Indian scenario, the oral cancers are reported late, due to lack of awareness and poverty. The aim of the present study was to determine the cytological and histopathological patterns of oral cavity lesions and to know the prevalence of various premalignant and malignant lesions in 100 patients. For cytological examination, FNAC and oral brush cytology was conducted and histopathological study of biopsy specimen was also done and compared. This comprehensive investigation has led to the conclusion that squamous cell carcinoma is the most malignant tumor seen dominantly affecting the rural male population.The benign lesions acknowledged were the cysts and vesiculo-bullous lesions, noticed predominantly in urban females. Leukoplakia emerged as the most common premalignant lesion. Clinically the various lesions presented as mass, ulcer, plaque and cysts. The sites involved primarily are tongue and buccal mucosa. Awareness regarding the hazards of indiscriminate use of tobacco and smoking can reduce its incidence in general population.
The Spectrum of Oral Pathology Specimens: A Histopathologic Analysis of 442 Specimens
Jordan Medical Journal
Background Aims: Diseases of the oral cavity are heterogenous regarding their etiology, pathogenesis, histogenesis and clinical outcomes. The aim of this study was to examine the frequency of oral diseases encountered in our experience. Methods: The archives of pathology at Jordan University Hospital were retrospectively searched for oral cavity specimens from 2013–2020. Fisher’s exact test was performed to examine the statistical difference between the pathologic diagnosis and clinical variables. One-way ANOVA was used to analyze the differences in the mean of age between the different pathologic groups. Results: A total of four-hundred and forty-two cases were retrieved. There were 232 (52%) females and 210 (48%) males, ranging in age from 3–87 years (mean 43). Inflammatory and reactive diseases were the most common, constituting 147 (33%) of all specimens, followed by 139 (31%) benign neoplasms, 114 (26%) cysts, and 42 (10%) malignant diseases. Lichen planus was the most common i...
Agreement between clinical and histopathological diagnoses of oral lesions
RGO.Revista Gaúcha de Odontologia (Online), 2010
The present study aimed to assess the rate of agreement between clinical and histopathological diagnoses and to report the frequency of completed forms for specimens that were subjected to histopathological examination and retrospectively examined. Data from 8,168 specimens submitted to histopathological examination were retrieved from the records. A total of 5,368 cases were included. Agreement was defined based on the definition of lesion nature according to its diagnostic category. Sensitivity, specificity, and positive and negative predictive values were calculated for each diagnostic category. The highest rate of agreement was observed for periapical lesions (92.6%), followed by potentially malignant disorders (90.1%) and non-neoplastic proliferative disorders (89.3%). Low rates of histopathological confirmation of the clinical impression were observed for mesenchymal tumors (25.0%) and cysts (44.2%). Sensitivity values were > 0.70 for all lesions, except for cysts (0.51). Specificity was relatively high, ranging from 0.97 to 1.00. The frequency of incomplete biopsy forms ranged from 16.8% (malignant tumors of oral mucosal epithelium) to 51.0% (nonspecific inflammatory reaction). The most frequently completed biopsy forms corresponded to epithelial malignant tumors (83.2%) and glandular inflammation (72.3%). In conclusion, there was an acceptable level of agreement. The low level of completeness of biopsy forms indicates little awareness about the relevance of gathering detailed information during clinical examination.
International Journal of Dentistry
Objective. Proper diagnosis plays a key role in the treatment and prognosis of all diseases. Although histopathological diagnosis is still known as the gold standard, final diagnosis becomes difficult unless precise clinical descriptions are obtained. So, this study aimed to evaluate the concordance of the clinical and histopathological diagnoses of all oral and maxillofacial biopsy specimens in a 12-year duration. Materials and Methods. Archive files and clinical findings related to 3001 patients who had been referred to the Department of Oral Pathology during a 12-year period were reviewed. The recorded information in files included age, sex, lesion’s location, clinical and histopathological diagnoses, and specialty of dentists. Results. Out of 3001 cases included and reviewed in this study, 2167 cases (72.2%) were consistent between clinical and histopathologic diagnoses. Age, sex, and clinician’s specialty were indicated to have no significant effect on diagnosis (p values = 0.5...