Design of a Three-Helix Bundle Capable of Binding Heavy Metals in a Triscysteine Environment (original) (raw)

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Soft metal ions, Cd(II) and Hg (II), induce triple-stranded α-helical assembly and folding of a de novo designed peptide in their trigonal geometries

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The role of protonation and metal chelation preferences in defining the properties of mercury-binding coiled coils

Kim Sharp

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Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α 3 DIV, that Sequesters Toxic Heavy Metals

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Comparison of the Binding of Cadmium(II), Mercury(II), and Arsenic(III) to the de Novo Designed Peptides TRI L12C and TRI L16C

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Joanna Grzyb

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Cu(I) binding properties of a designed metalloprotein

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Histidine Analog Amino Acids Providing Metal-Binding Sites Derived from Bioinorganic Model Systems

Ulf Diederichsen

European Journal of Organic Chemistry, 2009

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Synthesis of functionalized de novo designed 8?16 kDa model proteins towards metal ion-binding and esterase activity

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Organic & Biomolecular Chemistry, 2007

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Metal-Directed Protein Self-Assembly

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Modular and Versatile Hybrid Coordination Motifs on α-Helical Protein Surfaces

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Inorganic Chemistry, 2010

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Toward the de Novo Design of a Catalytically Active Helix Bundle: A Substrate-Accessible Carboxylate-Bridged Dinuclear Metal Center

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Robust and Versatile Host Protein for the Design and Evaluation of Artificial Metal Centers

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ACS Catalysis, 2019

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pH dependent binding in de novo hetero bimetallic coiled coils

Barbara Ciani

Dalton transactions (Cambridge, England : 2003), 2018

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Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography

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Computational Design and Characterization of a Monomeric Helical Dinuclear Metalloprotein

Janez Mavri

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Characterization of interactions and metal ion binding sites in proteins

Robert Jernigan

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Metalated peptide fibers derived from a natural metal-binding peptide motif

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Arwa Makki

2016

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Towards the role of metal ions in the structural variability of proteins: CdII speciation of a metal ion binding loop motif

Béla Gyurcsik

Metallomics, 2011

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Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils

John Stuckey

Proceedings of the National Academy of Sciences, 2007

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Proteins as diverse, efficient, and evolvable scaffolds for artificial metalloenzymes

Woon Ju Song

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A helix–coil transition induced by the metal ion interaction with a grafted iron-binding site of the CyaY protein family

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Designing a functional type 2 copper center that has nitrite reductase activity within -helical coiled coils

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Development of artificial metalloenzymes via covalent modification of proteins

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