Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009 (original) (raw)
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Incidence of Oral Cancer in a Tertiary Cancer Centre of Nepal: A Retrospective Study
2021
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Trend of Head and Neck Cancers in a National Tertiary Cancer Hospital of Nepal from 2012 to 2017
South Asian Journal of Cancer
Introduction Head and neck cancers (HNCs) are increasing in Nepal and have become a major public health issue. This study aims to describe the trend of HNCs in a national tertiary cancer hospital in Nepal. Methods This was a cross-sectional study with secondary data analysis conducted at B.P Koirala Memorial Hospital, Chitwan, Nepal. The data were obtained from the medical record section and included all new HNC cases registered from 2012 to 2017. Analysis was done using Statistical Package for Social Sciences version 17. Subgroup analysis was done according to age, gender, site, and year. Results A total of 4,582 new HNCs were registered, of which 3,097 (67.6%) were males and 1,482 (32.4%) were females. Lip and oral cavity cancers (46.5%) were the most common HNCs followed by tonsil and pharynx (18.0%) and larynx (15.8%). The trend of HNCs shows a steady rise in incidence with difference according to the sites. HNCs were more common among males than females except for thyroid cance...
Asian Pacific journal of cancer prevention : APJCP, 2012
Regional cancer epidemiology is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the pattern of head and neck cancer in western Nepal and hence an attempt was here made to evaluate the situation based on hospital data, which provide the only source in the western region of Nepal. A clinicopathological analysis of head and neck cancers treated between 2003 and 2006 in Manipal Teaching Hospital affiliated to Manipal College of Medical Sciences, Pokhara, Western Development Region, Nepal was performed. A total of 105 head and neck cancer cases were identified with a male to female ratio of 1.8:1. The median ages of male and female patients were 62 and 64 years, respectively. Ninety-seven (92.4%) of the cancer patients were suffering from carcinoma, three (2.9%) had blastoma, three (2.9%) had sarcoma, and two (1.9%) had lymphoma. The majority (61.9%) of carcinoma cases were squamous cell carcino...
Journal of Institute of Science and Technology
Oral cancer is becoming very common and increasing day by day in Nepal. It ranks 6th in the world and 5th in Nepal among all types of cancer as of 2018. This is a hospital-based retrospective study. Required details of 128 patients who underwent surgery from 1st April 2018 to 30th October 2019 in Nepal Cancer Hospital and Research Center, Lalitpur. Data were collected age-wise, sex-wise, site-wise, and stage-wise prevalence was figured out. The data were analyzed using MS excel 2007. It was found that males were more commonly affected than females with the mean age for males at diagnosis being 53.3 years and females being 55.62 years. The tongue was the most affected site followed by GBS then buccal mucosa and RMT. Most people knew about cancer growing on them only at advanced stages.
Oral cancer is one of the most common cancer in India. The aim of this study was to analyze retrospectively the demographic, histopathological and clinical profile of oral squamous cell carcinoma patients who attended a tertiary level care referral hospital in Jharkhand. A total of 324 biopsy proven cases of OSCC were studied. The data was collected for a period of June 2015 to December 2017. The cases were analyzed in terms of age,gender,duration of symptoms,habits(tobacco and alcohol consumption),site of primary tumour and stage at presentation and the results were formulated to chart the trends. Male to female ratio was 2.48:1. Most of the patients of OSCC belonged to the age group of 51-60 years(26.54%). Buccal mucosa was found to be the most common primary site of involvement. Majority of the patients presented in stage IVA (40.12%). Well differentiated SCC (56.79%)was the most predominant histological variant in this study. This study hence showed that OSCC is very widespread in this region and majority of cases presented at advanced stages due to lack of awareness. Early detection and intervention is required to decrease the morbidity and mortality associated with oral squamous cell carcinoma.
Epidemiological Study on Oral Cancer from Various Districts of Nepal 2013-2016
International Journal of Scientific Research in Science and Technology, 2020
Cancer epidemiology can be used to identify events that increases or decreases cancer incidence in specific populations. Oral cancer, also known as mouth cancer, is cancer of the lining of the lips, mouth, or upper throat. Oral cancer incidence doesn't mean that only one bodily cancer but it covers the lip, mouth, palate, gum, and above all the cavity along with the other unspecified sides. Cancer of the oral cavity (Oral cancer) is the 11th most common malignancy in the world, despite the general global trend of a slight decrease in the incidence of oral cancer, tongue cancer incidence is increasing. About 90% of tumors are subtyped to oral Squamous cell carcinoma (OSCC). The incidence and mortality of this tumor shows variability according to the geographic location in which it is diagnosed, however in the last decade an increase was seen in the percentage of young patients, especially patients with tongue cancer. Various hospital based cancer researches showed that Cancer incidence including oral cancer burden in Nepal was increasing every year. But exact cancer incidence, death and relevant community based details of cancer is unknown. Therefore the aim of this study is to determine the incidence of oral cancer and assess its trend in the fifteen districts of Nepal for 2013-2016 A.D. This population based descriptive epidemiological study was based on secondary data derived from various sources where recorded new oral cancer every year since January 2013 to December 2016. Among the reported cases of oral cancer topography, other and unspecified parts of tongue C 02 was the first leading cancer site followed by other and unspecified parts of mouth C 06 and gum C03 for both sex. Among the female cases other tongue C 02 was the leading cancer cases followed by other mouth C 06 and gum C03. Similarly, other tongue C02 was the most common cancer among males, followed by other mouth C 06 and gum C 03. Oral cancer was found to be increased in the year 2013 and 2014 whereas relatively decreased in 2015 A. D. as because, the earthquake of 2015 was a major factor to access the cancer diagnosis and treatment which decrease the patient flow at hospital and other data source institution. According to collected data oral cancer was increased in 2016. The trend of oral cancer was seen to be fluctuating yearly during the study period. Though well organized awareness activities, HPV vaccination and screening programs are still needed to prevent and control the incidence of oral cancer in our communities.
NPRC Journal of Multidisciplinary Research, 2024
Background: Oral cancer is one of the most prevalent and leading causes of mortality in certain regions, like South-Central Asia. The incidence of oral cancer in Nepal is also increasing. Oral cancer is preventable and treatable if diagnosed in an early stage. The study conducted at B.P. Koirala Memorial Cancer Hospital (BPKMCH) in Bharatpur, Nepal, was aimed at assessing the epidemiological profile of oral cancer patients attending BPKMCH. Methods: A descriptive cross-sectional study design was used to assess the epidemiological profile of oral cancer, and 50 patients were included in this study during January to July 2023. A semistructured interview schedule was developed, which has 3 parts, viz., i. socio-demographic variables, ii. Lifestyle-related factors and iii. Clinical profile of oral cancer, to obtain the information from the respondents. Results: The study findings revealed that out of 50 majorities of respondents (88%) were male. According to the religion, most of them (84%) were Hindu, and likewise, according to ethnicity, about half of them (40%) belong to Madeshi, followed by 30% Brahmin/Chhetri. Similarly, most of the respondents (90%) were married. Regarding the exposure to risk factors, half of the respondents (50%) had habits of smoking consumption, More than half (68%) had the habit of tobacco consumption, near to half (40%) had the habit of Gudka consumption, and 68% had the of oral cancer. Similarly, about one-third (30%) of respondents had stage IV, followed by 28% stage II, 26% stage I, and only a few (14%) stages in III disease; all the oral cancer was OSCC. Concerning the treatment modalities, 36% of respondents had surgery, near to one quarter (20%) received chemotherapy, 10% received radiation therapy, and 30% of respondents had surgery with adjuvant therapy. Conclusion: The study found that the majority of oral cancer patients attending BPKMCH were between the ages of 30 and 45 and were predominantly male. Smoking, tobacco, and Gudka consumption are the main risk factors for oral cancer. The risk assessment approach and screening program should be focused on preventing oral cancer.
Journal of Nepal Medical Association, 2021
Introduction: Head and neck cancer is the sixth most common cancer in the world. The disease burden is increasing at an alarming rate in developing Southeast Asian countries. This study aims to report the histopathological spectrum of oral cavity lesions at a tertiary cancer center in central Nepal. Methods: This study included all those cases of oral cavity lesions, of which diagnostic biopsy was done from January 2018 to December 2019. The data were retrieved from the Department of Pathology of BP Koirala Memorial Cancer Hospital. The study proposal was approved by the Institutional Review Committee at BPKMCH (Ref: 247/2020) on 28th June 2020. Convenience sampling was done. Data was analyzed using Statistical Package for the Social Sciences version 20 using descriptive statistics. Results: A total of 851 cases of oral cavity lesions were included in this study. The mean age of the study population was 55.9 years, with male to female ratio of 3:1. Malignant lesions composed of 472 ...
BMC Oral Health, 2016
Background: The main objective of this study was to describe selected clinico-pathological characteristics of Oral Squamous Cell Carcinoma (OSCC) in Sri-Lanka. Materials & methods: The study sample comprised of eight hundred and ninety six biopsies diagnosed as OSCC. The clinical and histopathological features were analyzed using the Chi-square test. Results: Of the 896 biopsies, 801 were primary OSCCs, while 95 were recurrent OSCCs. Majority of the patients (78 %) were in the 5 th to 7 th decades of life and showed a male predilection. The buccal mucosa was the commonest site of primary OSCC comprising of 43 % of the sample. Of the primary OSCCs, with known TNM stage, 86 % were in stage 3&4 and majority (59 %) of stage 4 tumours showed tumour at one or more excision margins. Of the recurrent OSCC, 46 % developed their recurrences within one year of the excision of the primary tumour. Conclusion: In Sri-Lanka, OSCC is a major problem. Only half the patients had completely excised tumours (with clearance of >5 mm at all excision margins) at operation, and recurrences appeared early. This data should be considered in the future management policy of OSCC in Sri-Lanka.
Kathmandu University medical journal, 2016
Background Head and neck is one of the most prevalent site for cancers along with lungs, cervix, breast and stomach. Hospital based cancer registries required for effective evaluation of diagnosis and management of cancer is inadequate in Nepal. Cancer registry system established by WHO is acquired by seven major hospitals in our country. However, data from tertiary health care centres like ours remain undocumented. Objective The objective of this study is to perform retrospective analysis of clinicohistopathological types of head and neck lesions which were eventually diagnosed as cancer in Dhulikel Hospital, a tertiary health care centre of Central East Nepal. Method Data regarding head and neck lesions diagnosed as cancer (January 2001- December 2014) were extracted from the archives of Department of General Pathology. These cases were categorised according to demographic profile, site of cancer and histological diagnosis. Result A total of 240 cases matched the inclusion criteri...