Miltefosine resistance in Leishmania donovani involves suppression of oxidative stress-induced programmed cell death (original) (raw)

Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania

A. Lopéz-Gonzalvez

Analytical and Bioanalytical Chemistry, 2014

View PDFchevron_right

Miltefosine for Old World cutaneous leishmaniasis: An experimental study on Leishmania major infected mice

Shereen Mossallam

View PDFchevron_right

Efficacy of Miltefosine for the Treatment of American Cutaneous Leishmaniasis

J. Liliana Lopez

American Journal of Tropical Medicine and Hygiene, 2010

View PDFchevron_right

Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress

Aditya Verma

PLoS neglected tropical diseases, 2017

View PDFchevron_right

Miltefosine Effectively Modulates the Cytokine Milieu in Indian Post Kala-Azar Dermal Leishmaniasis

Susmita Roy

The Journal of Infectious Diseases, 2011

View PDFchevron_right

Identification of Miltefosine resistance associated genes in Leishmania donovani

Deepak Deep

View PDFchevron_right

Possible Mechanism of Miltefosine-Mediated Death of Leishmania donovani

Navin Kumar

Antimicrobial Agents and Chemotherapy, 2004

View PDFchevron_right

Miltefosine induces apoptosis in arsenite-resistant Leishmania donovani promastigotes through mitochondrial dysfunction

Navin Verma

Experimental Parasitology, 2007

View PDFchevron_right

Membrane sterol depletion impairs miltefosine action in wild-type and miltefosine-resistant Leishmania donovani promastigotes

Mohamed Ben Brahim

Journal of Antimicrobial Chemotherapy, 2009

View PDFchevron_right

Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes

Claudia D'Avila-Levy

Memórias do Instituto Oswaldo Cruz, 2011

View PDFchevron_right

Induction of apoptosis in host cells: a survival mechanism for Leishmania parasites

Giulia Getti

Parasitology, 2008

View PDFchevron_right

Phase IV Trial of Miltefosine in Adults and Children for Treatment of Visceral Leishmaniasis (Kala-Azar) in Bangladesh

Byron Arana

American Journal of Tropical Medicine and Hygiene, 2011

View PDFchevron_right

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use

K. Seifert

Drug Resistance Updates, 2006

View PDFchevron_right

Miltefosine Induces Apoptosis-Like Death in Leishmania donovani Promastigotes

christian bories

Antimicrobial Agents and Chemotherapy, 2004

View PDFchevron_right

Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovani

RUCHI SINGH

Parasitology Research, 2014

View PDFchevron_right

Novel inhibitors of leishmanial dihydrofolate reductase

shafinaz chowdhury

Bioorganic & Medicinal Chemistry Letters, 2001

View PDFchevron_right

CpG oligodeoxynucleotide augments the antileishmanial activity of miltefosine against experimental visceral leishmaniasis

w haq

Journal of Antimicrobial Chemotherapy, 2010

View PDFchevron_right

Functional Cloning as a Means to Identify Leishmania Genes Involved in Drug Resistance

Kohelia Choudhury

Mini-reviews in Medicinal Chemistry, 2006

View PDFchevron_right

Leishmania donovani exploits myeloid cell leukemia 1 (MCL-1) protein to prevent mitochondria dependent host cell apoptosis

Shreyasi Palit

Journal of Biological Chemistry, 2015

View PDFchevron_right

Identification of a Leishmania infantum gene mediating resistance to ‘ and SbIII

Kohelia Choudhury

International Journal for Parasitology, 2008

View PDFchevron_right

Sensitivity of Leishmania spp. to Glibenclamide and 4-Aminopiridine: A Tool for the Study of Drug Resistance Development

Alicia Ponte

Memórias do Instituto Oswaldo Cruz, 1997

View PDFchevron_right

Iron superoxide dismutase contributes to miltefosine resistance inLeishmania donovani

Jalaja Veronica

The FEBS Journal, 2019

View PDFchevron_right

Novel leads against miltefosine-unresponsive Leishmania donovani

Anil Saikia

Antimicrobial Agents and Chemotherapy, 2015

View PDFchevron_right

Drug Susceptibility in Leishmania Isolates Following Miltefosine Treatment in Cases of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis

Vijay Kumar Prajapati

PLOS Neglected Tropical Diseases, 2012

View PDFchevron_right

Novel Agents against Miltefosine-Unresponsive Leishmania donovani

Anil Saikia

Antimicrobial Agents and Chemotherapy, 2015

View PDFchevron_right

Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A)

Gagandeep Singh

International Journal of Antimicrobial Agents, 2008

View PDFchevron_right

Leishmania sp.:Growth and Survival Are Impaired by Ion Channel Blockers

Alicia Ponte

Experimental Parasitology, 1998

View PDFchevron_right

In vitro susceptibility of Leishmania donovani to miltefosine in Indian visceral leishmaniasis

Vijay Kumar Prajapati

The American journal of tropical medicine and hygiene, 2013

View PDFchevron_right