How little is known about the role of human Foxp3+ Tregs in tumors (original) (raw)

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

Jocelyne Demengeot

European Journal of Immunology, 2009

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Stability and Maintenance of Foxp3+ Treg Cells in Non-lymphoid Microenvironments

Thomas Korn

Frontiers in Immunology

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Induction, control, and plasticity of Treg cells: The immune regulatory network revised?

Vincenzo Barnaba

European Journal of Immunology, 2013

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Role of CD4+CD25+FOXP3+ TReg cells on tumor immunity

Soehartati Gondhowiardjo

Immunological Medicine

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Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

C. Castelli

Clinical Cancer Research, 2011

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Lymph Node Occupancy Is Required for the Peripheral Development of Alloantigen-Specific Foxp3+ Regulatory T Cells

Adam Yopp, Jordi Ochando

The Journal of Immunology, 2005

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The origin of tumour-infiltrating regulatory T cells

João Freitas

2019

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FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy

Naser Elkum, Said Dermime

BMC Cancer, 2008

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Regulatory T-Cell (Treg) hybridoma as a novel tool to study Foxp3 regulation and Treg fate

rahul sharma

Journal of Autoimmunity, 2011

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Foxp3 Expressing CD4CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells1

Guy Gorochov

2000

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Dynamics of peripheral tolerance and immune regulation mediated by Treg

Kajsa Wing

European Journal of Immunology, 2009

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Site-specific anti-tumor immunity: Differences in DC function, TGF-β production and numbers of intratumoral Foxp3+ Treg

Karl Frei

European Journal of Immunology, 2009

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Skin Melanoma Development in ret Transgenic Mice Despite the Depletion of CD25+Foxp3+ Regulatory T Cells in Lymphoid Organs

Christine Falk, S. Kimpfler

The Journal of Immunology, 2009

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The T-cell Receptor Repertoire of Tumor-Infiltrating Regulatory T Lymphocytes Is Skewed Toward Public Sequences

Claude Leclerc

Cancer Research, 2012

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Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Response Mediated by FOXP3+ T Cells and Immunoregulatory Molecules

Laurie Rund

Frontiers in Immunology

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Recruitment and Expansion of Tregs Cells in the Tumor Environment—How to Target Them?

Christine Ménétrier-caux

Cancers

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Contribution of regulatory T cells to cancer: A review

Masoud Najafi

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Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3+ CD4+ T cells

Michal Kuczma

PLoS ONE, 2010

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Reciprocal effects of Th1 and Treg cell inducing pathogen-associated immunomodulatory molecules on anti-tumor immunity

Andrew Jarnicki

Cancer Immunology, Immunotherapy, 2007

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Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node

Eliane Piaggio

Nature Communications

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

Madhav Sharma

Journal of Clinical Investigation, 2007

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Regulatory T-cell stability and plasticity in mucosal and systemic immune systems

Mitchell Kronenberg

Mucosal Immunology, 2010

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Peripherally induced tregs - role in immune homeostasis and autoimmunity

mahesh yadav

Frontiers in immunology, 2013

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Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients

Eliane Piaggio

Nature Communications

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Antitumor Immunity Graft-versus-Host Disease and Generation: Implications in Regulatory Lymphocyte + FOXP3

A. Radlovic, Jean-paul Remy-martin

2000

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Treg Depletion Inhibits Efficacy of Cancer Immunotherapy: Implications for Clinical Trials

Pedro Lowenstein

PLoS ONE, 2008

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Treg cells to the rescue

David Fox

Arthritis & Rheumatism, 2012

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Competition for cytokines: Treg cells take all

Alexander Scheffold

Nature Immunology, 2007

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Examining the immune response in sentinel lymph nodes of mice and men

Hong-Ming Hu

European Journal of Nuclear Medicine, 1999

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Tumor-associated Tregs obstruct antitumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells

Saheed Oseni

Journal for ImmunoTherapy of Cancer

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Regulatory lymphocytes: the dice that resolve the tumor endgame

Gaurisankar Sa

Applied Cancer Research, 2020

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Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner

TT ZHANG

Clinical Immunology, 2010

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Tumor Regulatory T Cells Potently Abrogate Antitumor Immunity

Louis Falo

The Journal of Immunology, 2009

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Depletion of tumor-induced Treg prior to reconstitution rescues enhanced priming of tumor-specific, therapeutic effector T cells in lymphopenic hosts

Bernard Fox

European Journal of Immunology, 2009

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