Giant-cell tumour of the tendon sheath: A review (original) (raw)
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Giant Cell Tumor of Tendon Sheath – A Case Report
IOSR Journals , 2019
Introduction: They are rare soft tissue tumors of hand. They are considered to be arising due to minute repeated tumors. There are also reported incidences of malignant giant cell tumors. Treatment would be complete surgical excision. Case report: A 22 year old male came with complaints of a slow growing swelling in the right great toe of size 4*3 cms which is firm and not mobile. Fnac showed features suggestive of inflammation. Lesion was completely excised under regional anesthesia. Post operative biopsy showed giant cell tumor of the tendon sheath. Post operative follow up patient was comfortable and asymptomatic. Discussion: They are mostly seen in hand and foot of women and are seen mostly in mid 30-40’s. They appear as a slow growing, painless tumors. They are pre operatively diagnosed by USG, MRI and Fnac. They are treated by complete surgical excision. They have a high recurrence rate. Post operative radiotherapy shows no recurrence
A Case Series of Giant Cell Tumor of Tendon Sheath
IOSR Journals , 2019
Giant cell tumor of tendon sheath is a relatively rare non-malignant soft tissue tumor arising from the synovial cells and is associated with high recurrence rate. However it is the second most common tumor in hands after ganglion cysts. Few factors considered for recurrence are proximity of distal inter phalangeal joints, presence of degenerative joint disease, pressure erosions in radiograph, increased mitotic activity. But only consistent observation found is incomplete excision of the tumor which leads to recurrence.Here we present a case series comprising of 4 cases over a period of 2 years for whom marginal excision was done and they were kept on regular follow up without any recurrence.
Giant cell tumor of tendon sheath: An institutional experience
International Journal of Clinical and Diagnostic Pathology, 2020
Giant Cell Tumor of Tendon Sheath (GCTTS) is the second most common benign tumour affecting hand after ganglion. It more commonly affects middle aged women with index finger being the most commonly affected site. There is high propensity of recurrence following surgical excision. The objective of this study was to review all cases of GCTTS received in our department and to study the age and gender distribution, location and histological features of the same.
Giant Cell Tumour of the Tendon Sheath: A Case Report
Journal of Evolution of medical and Dental Sciences, 2016
INTRODUCTION: The giant cell tumor of tendon sheath is among the more common soft tissue tumors of the hand. It is a slowly progressive, usually painless, rubbery mass predominating on the radial three digits of the hand and is typically identified adherent to the digital flexor tendon sheath of the hand. The histology is variable but the tumors consistently contain multinucleated giant cells and xanthoma cells. CASE PRESENTATION: A case report of a 57 years old female patient who came with a diffuse, painless swelling on the radial aspect of middle finger of the right hand at the Orthopedic OPD of our institution. MANAGEMENT & OUTCOME: A planned operative procedure was done. After clinical examination and other investigations, a careful excision of the mass was done by detaching it from the underlying tendon sheath. The tissue was sent for biopsy to two different labs for examination. The reports were confirmed as Giant Cell tumor of the tendon Sheath. DISCUSSION: A giant cell tumo...
Giant cell tumour of tendon sheath: a review
Introduction: Tumors of hand are uncommon entities. Giant Cell Tumour of Tendon Sheath (GCTTS) is the second most common soft tissue tumour, next only to ganglion cysts. Method and Result: We report two cases of giant cell tumours of tendon sheath. One arose from the flexor tendon in the palm of a 22 years old female and the second was a recurrence of a digital giant cell tumour. The various aspects of giant cell tumours of tendon sheath are reviewed.
Giant cell tumour of tendon sheath: a case
A 47-year-old female presented with yellowish white painless nodule on right thumb of 2year duration. On the basis of clinical and histopathological findings she was diagnosed as a case of giant cell tumour of the tendon sheath.
Giant cell tumor of tendon sheath: a multicentric presentation
Case Reports in Clinical Pathology, 2014
Giant cell tumor of the tendon sheath (GCTTS) is a relatively common soft tissue neoplasm arising from the tendon sheaths of upper and lower extremities. However, the incidence of GCTTS at multiple sites is not yet reported in literature which is extremely rare. Here we are reporting a case of a 21 year female presenting with slow growing, firm swellings on bilateral elbow and tendoachilis region. Fine needle aspiration was done from all the sites which revealed the features of GCTTS. This case highlights the unusual multicentric presentation of GCTTS.
Histopathology, 1992
Tendon sheath tumours: a pathological study of the relationship between giant cell tumour and fibroma of tendon sheath Thirty-nine soft tissue lesions occurring on the distal aspect of the limbs have been selected because of histological features consistent with those recognized for giant cell tumour of tendon sheath or fibroma of tendon sheath. In spite of the frequent occurrence of such lesions at the stated sites, they were rarely correctly diagnosed pre-operatively. Using a scoring system to grade specified histological features, a blind evaluation to reclassify these 39 lesions was undertaken. This resulted in 2 9 cases of giant cell tumour of tendon sheath, six fibromas of tendon sheath and four 'transitional stage' lesions. Despite the heterogeneous morphology of these categories, there were no significant differences in the clinical features of affected patients. The existence of a 'transitional stage' lesion, combined with the homogeneous clinical picture of all categories, supports the concept that fibroma of tendon sheath is the end and sclerosing stage of giant cell tumour of tendon sheath, probably consequent on progressive vascular impairment. There is a need for pathologists to recognize the transitional stage lesions so as to avoid their inclusion with other diagnostic entities. For this group the name 'giant cell tumour of tendon sheath-transitional stage lesion' is suggested.
Giant cell tumor of tendon sheath: Cytomorphologic and radiologic findings in 41 patients
Diagnostic Cytopathology, 2012
Giant cell tumor of tendon sheath (GCTTS) is a common soft tissue lesion and presents as a firm, slow-growing, non-tender mass adjacent to the tendon sheath. It can be further classified into diffuse or localized types based on its growth pattern. Using cytomorphologic analysis, we assessed the feasibility of fine-needle aspiration (FNA) as an initial diagnostic modality for GCTTS. Forty-one cases of image-guided FNA of GCTTS were retrospectively retrieved from the archives of The Johns Hopkins Hospital. Clinical information, imaging studies, histopathology, and other ancillary studies were also reviewed. The majority of the cytology specimens demonstrated hypercellularity. A uniform population of spindled to polygonal stromal cells constituted more than half of the cellularity. Other cell types frequently present included multinucleated giant cells, hemosiderin-laden macrophages, and foamy histiocytes. Nuclear grooves or intranuclear pseudo-inclusions present in stromal cells were also distinctive cytomorphologic features, but only present in less than a quarter of the cases. Our study has shown the usefulness and accuracy of imaging-guided FNA as a diagnostic tool for GCTTS. Diagnostic accuracy can be optimized with a thorough review of clinical history, careful physical examination, and radiologic correlation. Diagn. Cytopathol. 2012;40:E94-E98. ' 2012 Wiley Periodicals, Inc.