StructureActivity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine (original) (raw)

Screening and analysis of acetyl-cholinesterase (AChE) inhibitors in the context of Alzheimer’s disease

Bhagath Kumar Palaka

Bioinformation, 2018

View PDFchevron_right

Discovery of Novel Acetylcholinesterase Inhibitor Implication for the Design of New Anti-Alzheimer Agents

Amir Zeb

View PDFchevron_right

Insilico Design and Discovery of Some Novel Ache Inhibitors for Treatment of Alzheimer’s Disorder

Manoj Kumar

View PDFchevron_right

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

Abdelouahid Samadi

European Journal of Medicinal Chemistry, 2012

View PDFchevron_right

Structure of acetylcholinesterase complexed with (−)-galanthamine at 2.3 Å resolution

alan kozikowski

FEBS Letters, 1999

View PDFchevron_right

Lessons from functional analysis of AChE covalent and noncovalent inhibitors for design of AD therapeutic agents

Chanoch Kronman, Baruch Velan

Chemico-Biological Interactions, 2005

View PDFchevron_right

Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer’s Disease

Amir Zeb

International Journal of Molecular Sciences

View PDFchevron_right

Understanding the quantitative structure–activity relationship of acetylcholinesterase inhibitors for the treatment of Alzheimer's disease

Anuradha Kaplish

View PDFchevron_right

Research Strategies Developed for the Treatment of Alzheimer’s Disease. Reversible and Pseudo-Irreversible Inhibitors of Acetylcholinesterase: Structure-Activity Relationships and Drug Design

MAURICIO ALCOLEA PALAFOX

Frontiers in Drug Design & Discovery, 2014

View PDFchevron_right

New Tacrine−Huperzine A Hybrids (Huprines): Highly Potent Tight-Binding Acetylcholinesterase Inhibitors of Interest for the Treatment of Alzheimer's Disease

Diego Muñoz-torrero, Nuria Vivas, Pelayo Camps

Journal of Medicinal Chemistry, 2000

View PDFchevron_right

Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease

Filip Zemek, Jan Korabecny, V Opletalová, Kamil Kuča

2010

View PDFchevron_right

Dual binding site acetylcholinesterase inhibitors: potential new disease-modifying agents for AD

Diana Fernanda Arana Gordillo

Journal of molecular neuroscience : MN, 2006

View PDFchevron_right

The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer’s Disease

Immacolata Vecchio

Journal of Central Nervous System Disease, 2021

View PDFchevron_right

New Acetylcholinesterase Inhibitors for Alzheimer's Disease

Abdu Adem

International Journal of Alzheimer's Disease, 2012

View PDFchevron_right

Proposing novel natural compounds against Alzheimer's disease targeting acetylcholinesterase

Nigar Çarşıbaşı, Münteha Girgin

Proposing novel natural compounds against Alzheimer’s disease targeting acetylcholinesterase, 2023

View PDFchevron_right

New Acetylcholinesterase Inhibitors for Alzheimer&# 39; s Disease

Abdu Adem

International Journal of Alzheimer's …, 2011

View PDFchevron_right

Synthesis and activity studies of N-[ω-N′-(adamant-1′-yl)aminoalkyl]-2-(4′-dimethylaminophenyl)acetamides: In the search of selective inhibitors for the different molecular forms of acetylcholinesterase

Luciano Cellai

Bioorganic & Medicinal Chemistry Letters, 1998

View PDFchevron_right

Research Article New Acetylcholinesterase Inhibitors for Alzheimer’s Disease

Abdu Adem

View PDFchevron_right

Molecular Modeling and Anticholinesterasic Activity of Novel 2-Arylaminocyclohexyl N,N -Dimethylcarbamates

Simone Aparecida Galerani Mossini, Miguel Junior, Gisele Gauze, Ernani Basso

Journal of the Brazilian Chemical Society, 2013

View PDFchevron_right

Chapter 53: Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease

René Amstutz

Progress in Brain Research, 1993

View PDFchevron_right

Biochemical Studies on a Novel Potent Acetylcholinesterase Inhibitor with Dualsite Binding for Treatment of Alzheimer’s Disease

Nikolai Danchev

2021

View PDFchevron_right

Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates

Lorena Ramirez

Chemico-Biological Interactions, 2010

View PDFchevron_right

Virtual Screening and Admet Analysis for Identification of Inhibitors Against Acetylcholin Esterase Associated with Alzheimer's Disease

Ankit Singh

International Journal of Pharmacy and Pharmaceutical Sciences

View PDFchevron_right

Acetyl cholinesterase: a potential target for Alzheimer’s disease intervention

Sandhya khadka

Journal of Patan Academy of Health Sciences, 2020

View PDFchevron_right