アデノ随伴ウイルスベクターを用いたモルモット蝸牛内への遺伝子導入 (original) (raw)

遺伝的アルゴリズムによる50kg級小型衛星の熱制御システム設計

JOURNAL OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, 2007

A method is presented for designing the thermal control system for 50 kg-class micro-satellite using a genetic algorithm. Replacing the thermal control system into a heat transfer model, i.e. a thermal network model, the problem is treated as an optimization problem to find suitable combinations of adapted thermal control elements under admissible function keeping the controlled temperature within a selected band width. Admissible function used herein consists of two parameters; the one is a slope of temperature variation and the second is an amplitude of temperature variation during on orbital motion of satellite. To demonstrate the validity of the proposed method, the method is applied to two examples for the thermal control system design of a 50 kg-class micro-satellite, tentatively called "SOHLA-1", under development.

バングラデシュにおけるウシの泌乳能力に関する統計遺伝学的研究

2000

Kyoto University (京都大学)0048新制・課程博士博士(農学)甲第8568号農博第1151号新制||農||810(附属図書館)学位論文||H12||N3447(農学部図書室)UT51-2000-M32京都大学大学院農学研究科応用生物科学専攻(主査)教授 佐々木 義之, 教授 守屋 和幸, 教授 矢野 秀雄学位規則第4条第1項該

セルラーゼ処理による部分カルボキシメチル化綿のモルホロジー観察

FIBER, 2005

In our previous paper, cotton fabrics which had been modified by carboxymethylation so as to have the degree of substitution of 0.02~0.16 were treated with a commercial cellulase preparation. The modification by carboxymethylation for cotton fabrics apparently inhibited weight loss activity and saccharification activity of cellulase. In this study, by scanning electron microscopy, we observed morphological changes of fiber surface of modified cotton fabrics treated with a commercial cellulase preparation. For unmodified cotton fabrics, deep bias cracks were produced and clear fibrillar layers appeared on the fiber surface by synergistic reaction of cellulase components. On the other hand, for cotton fabrics modified by carboxymethylation, we observed inhibition of catalytic reaction of some cellulase components, as a result of no deep cracks and no appearance of fibril layers on fibers. In addition, we confirmed, by measurements of FT-IR spectra and K/S values of fabrics dyed with a basic dye, that carboxymethyl groups in modified cotton fabrics remained even after treatment with cellulase. From these results, it is suggested that the change in the activity of each cellulase component on modified cotton can affect the synergistic action of cellulases, and consequently the morphology of fiber surface of modified cotton changes compared with unmodified cotton.

家兎下肢虚血モデルに対する脱分化脂肪細胞(DFAT) 自家移植の効果

Journal of Nihon University Medical Association, 2013

Mature adipocyte-derived dedifferentiated fat (DFAT) cells exhibit high proliferative activity and multi-lineage differentiation potential similar to mesenchymal stem cells (MSCs). In the present study, we examined the efficacy of angiogenic activity and safety of autologous DFAT cell transplantation in rabbits with hindlimb ischemia. The number of microvessel branching points in the ischemic area in the DFAT group was significantly greater than in the Control group. Autologous DFAT cell transplantation was performed easily and safely without any adverse effects up to 4 weeks after injection. DFAT cells may be an attractive cell source for therapeutic angiogenesis.