Association between blood marker analyses regarding physical fitness levels in Spanish older adults: A cross-sectional study from the PHYSMED project (original) (raw)
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Comparison of physical fitness and lipid profile in active and inactive middle-aged men
European Journal of Experimental Biology, 2014
The purpose of this study was to compare physical fitness (Vo2max, endurance, power, agility and flexibility) and lipid profile (triglycerides, cholesterol, VLDL, LDL, and HDL) in active and inactive middle-aged men. 30 male volunteers who aged 40-60 years were assigned in active (n=15) and inactive (n=15) groups. Subjects of the active group participated continuously in at least one to three sessions of physical activity per week over the past 10 years, while subjects in inactive group had no specific exercises. Data Analysis was performed using independent t-test statistical method. Significance level of the test was considered P≤0.05.Research results showed significant differences in Vo2max, endurance, power, agility and flexibility between the active and inactive groups (p=0.0001), but no significant differences were observed between the two groups in lipid profile levels(p>0.05).Lack of significant differences in lipid profile seems to be the result of active group's hig...
American Journal of Therapeutics, 2010
Coronary artery disease is the main cause of death worldwide. Lipoprotein(a) [Lp(a)], is an independent risk factor for coronary artery disease in which concentrations are genetically regulated. Contradictory results have been published about physical activity influence on Lp(a) concentration. This research aimed to determine associations between different physical activity levels and Lp(a) concentration. A descriptive and cross-sectional study was made in 1340 randomly selected subjects (males = 598; females = 712) to whom a complete clinical history, the International Physical Activity Questionnaire, and Lp(a) level determination were made. Statistical analysis was carried out to assess qualitative variables relationship by x 2 and differences between means by one-way analysis of variance considering a P value ,0.05 as statistically significant. Results are shown as absolute frequencies, percentages, and mean 6 standard deviation according to case. Physical activity levels were ordinal classified as follows: low activity with 24.3% (n = 318), moderate activity with 35.0% (n = 458), and high physical activity with 40.8% (n = 534). Lp(a) concentration in the studied sample was 26.28 6 12.64 (IC: 25.59-26.96) mg/dL. Lp(a) concentration according to low, moderate, and high physical activity levels were 29.22 6 13.74, 26.27 6 12.91, and 24.53 6 11.35 mg/dL, respectively, observing statistically significant differences between low and moderate level (P = 0.004) and low and high level (P , 0.001). A strong association (x 2 = 9.771; P = 0.002) was observed among a high physical activity level and a normal concentration of Lp(a) (less than 30 mg/dL). A lifestyle characterized by high physical activity is associated with normal Lp(a) levels.
Associations of Aerobic and Strength Exercise with Clinical Laboratory Test Values
Medicine & Science in Sports & Exercise, 2017
Objectives Physical exercise may affect levels of blood-based biomarkers. However, exercise status is seldom considered in the interpretation of laboratory results. This study reports the associations between habitual exercise participation and clinical laboratory test results. Methods The effects of days per week of aerobic and strength exercise participation on laboratory test results for 26 biomarkers in young adults aged 18 to 34 years (n = 80,111) were evaluated using percentile distribution analyses and multivariate regression. Results In both men and women, more days per week of either aerobic or strength exercise were significantly associated with lower levels of glucose, hemoglobin A1c, LDL cholesterol, total cholesterol, triglycerides, estimated glomerular filtration rate, globulin, and C-reactive protein, and significantly higher levels of HDL cholesterol, creatinine, iron, and percent saturation (all p < .05). Type of exercise or gender influenced the observed relationships with exercise frequency for total cholesterol, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, uric acid, bilirubin, and iron binding capacity. Conclusions Physical exercise shifted the distribution of results into the direction suggestive of better health. Reported relationships may help clinicians and patients to better understand and interpret laboratory results in athletic populations and possibly re-evaluate interpretation of reference intervals for physically active populations.
Amount and Intensity of Physical Activity, Physical Fitness, and Serum Lipids in Men
Physical activity improves one's lipid profile and increases physical fitness. The present study was aimed at determining the association of amount and intensity of leisure time physical activity with serum lipid profile and physical fitness. A total of 537 healthy men aged 20-60 years were recruited in a quota sampling frame for measurement of physical activity energy expenditure at two different levels. The Minnesota Leisure Time Physical Activity Questionnaire was administered. Serum lipid and lipoprotein levels were measured, and all participants were given an exercise test. Physical activities with an intensity greater than 7 kcal/minute were significantly associated (p < 0.01) with a higher level of high density lipoprotein (HDL) cholesterol and a lower atherogenic index (total cholesterol: HDL cholesterol). Independently of other confounding variables, each average 100 kcal/day expended in leisure time physical activity with an intensity greater than 7 kcal/minute during the previous year was associated with an increase of 2.09 mg/dl (0.054 mmol/liter) in HDL cholesterol and a decrease of 0.23 in atherogenic index. However, only physical activity with an intensity greater than 9 kcal/minute was associated with decreases in total cholesterol, non-HDL cholesterol, and log(triglycerides). Better physical fitness was associated with physical activities of intensities above 5 kcal/minute. There is a threshold in the intensity of exercise associated with serum lipid profile (7 kcal/minute) and physical fitness (5 kcal/minute). Above the former threshold, the relation between amount of physical activity and lipid levels is linear for total cholesterol, HDL cholesterol, non-HDL cholesterol, and atherogenic index and is logarithmic for triglycerides. Am J Epidemiol 1996; 143:562-9.
Circulation, 1986
More than 3600 white men, from 30 to 79 years old and without a history of myocardial infarction, underwent submaximal treadmill exercise tolerance tests as part of their baseline evaluation for the Lipid Research Clinics Mortality Follow-Up Study. The exercise test was conducted according to a common protocol and coded centrally; depression of the ST segment by at least 1 mm (visual coding) and/or 10 ,V-sec (ST integral, computer coding) signified a positive test. Concurrent measurements of age, blood pressure, history of cigarette smoking, and plasma levels of lipids, lipoproteins, and glucose, as well as other coronary risk factors, were obtained. Cumulative mortality from cardiovascular disease was 11.9% (22/185) over 8.1 years mean follow-up among men with a positive exercise test vs 1.2% (36/2993) over 8.6 years mean follow-up among men with a negative test. Threequarters (43) of these deaths were due to coronary heart disease. The relative risk for cardiovascular mortality associated with a positive exercise test was 9.3 before and 4.6 after age adjustment. Cardiovascular mortality rates were especially elevated (relative risk 15.6 before and 5.1 after age adjustment) among the 82 men whose exercise tests were adjudged "strongly" positive based on degree and timing of the ischemic electrocardiographic response. A positive exercise test was also moderately associated with noncardiovascular mortality; the relative risk for all-cause mortality was 7.2 before and 3.4 after age adjustment. The relative risk for cardiovascular mortality associated with a positive exercise test was not appreciably altered by covariance adjustment for known coronary risk factors other than age. A positive exercise test was a stronger predictor of cardiovascular death than were high plasma levels of low-density lipoprotein cholesterol, low plasma levels of high-density lipoprotein cholesterol, smoking, hyperglycemia, or hypertension. Its impact on risk of cardiovascular death was equivalent to that of a 17.4 year increment in age.
Effect of volume of participation in exercise programs on biochemical parameters of women
Revista Brasileira de Atividade Física & Saúde, 2022
The aim of the study was to evaluate the effect of the volume of participation in exercise programs offered in Primary Health Care (PHC), for 24 weeks on blood biochemical parameters of adult women. Three Basic Health Units in Rio Claro City (São Paulo) were selected and 2 exercise interventions were implemented with different volumes (3 weekly sessions, 90 minutes each; 2 weekly sessions, 60 minutes each). In total, 53 participants remained until the end of the interventions. Regardless of their number of absences, they were divided into 4 groups, according to the volume of participation (calculated individually according to the duration of sessions and the number of classes held), forming groups according to quartiles: Low Volume Group (LVG; 57.62 ± 9.97 years-old), Low Medium Volume Group (LMVG; 56.31 ± 12.18 years-old), High Medium Volume Group (HMVG; 53.00 ± 10.25 years-old), and High-Volume Group (HVG; 59.69 ± 7.66 years-old). Blood biochemical parameters were dosed using the ...
Effect of physical exercise on lipid metabolism in the elderly
Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2002
To assess the effect of regular physical exercise on plasma lipids and apoproteins in an elderly group. Sixty-three old people of both sexes, aged between 65 and 94, were randomly distributed between a test group (n = 31) and a control group (n = 32). The test group followed a program of physical exercise for eight months, with intensity of 60% to 80% of heart rate reserve, consisting of three weekly sessions, on alternate days, of 60 minutes each. Before the beginning of the program and eight months afterwards, blood samples were collected to assess total cholesterol, triglycerides, HDL-C, HDL2-C. HDL3-C, apo A1, apo B-100 and apo (a). The ratios total cholesterol/HDL-C, LDL-C/HDL-C, HDL2-C/HDL3-C and apo A1/apo B-100 were also calculated. In the test group total cholesterol, triglycerides, LDL-C, apo B-100, total cholesterol/HDL-C and LDL-C/HDL-C decreased significantly; HDL-C, HDL2-C, apo A1, HDL2-C/HDL3-C and apo A1/apo B-100 increased significantly; HDL3-C and apo (a) did not c...
Health Related Physical Fitness Levels of Elderly
Facta universitatis. Series physical education and sport, 2014
This study was designed to investigate the level of health-related physical fitness (HRPF) in the Novi Sad elderly. Forty-nine elderly people 73.22±5.04 years of age (20 females and 29 males) participated in this study. Their health status, body composition and HRPF were measured. The differences between the HRPF indicators between health risk factor groups were calculated using the one-way univariate analysis of variance (ANOVA), with a 95% confidence level (p < .05). The relationship between the health risk stratification factor and HRPF was assessed by Pearson's correlation coefficients (p < .05). Based on the Risk Factor Stratification, the participants were grouped into: a low risk-36.7%; moderate risk 16.3% and high risk group-46.9% of he participants. A statistically significant difference was noted in the hand grip strength between low risk and high risk participants (p = 0.04). A moderate negative relationship between the health risk factor and balance (r = .417) and cardiovascular fitness (r = .426) was noted. The analyses of the health status indicate prehypertension. The results of body composition show obesity, and the HRPF level indicates a high risk of cardiovascular disease, muscle strength at risk level, and flexibility and balance at a satisfactory level for this age.
Physical activity, physical fitness, and coronary heart disease risk factors
Medicine & Science in Sports & Exercise, 1995
The purpose of this study was: to validate metabolic equivalents (METs) · hr/week by comparing with maximal oxygen uptake (VO 2 max) as a measure of physical activities, to examine the relationships between METs · hr/week,VO 2 max, and coronary heart disease (CHD) risk factors according to the goals of METs · hr/week andVO 2 max in ml·kg −1 ·min −1 for health promotion set in the Exercise Guide 2006, and to examine which is more related with CHD risk factors: METs · hr/week oṙ VO 2 max in ml·kg −1 ·min −1 ? Subjects were 116 collegiate women. MET intensities were assigned to each specific activity.VO 2 max was estimated with a bicycle ergometer. METs · hr/week was significantly correlated (r = 0.514, p < 0.01) withVO 2 max in ml·kg −1 ·min −1 . After adjusting appropriate confounding factors in the forward stepwise multiple regression analyses, METs · hr/week was significantly positively related with high-density lipoprotein cholesterol (HDL-C), while the estimatedVO 2 max in ml·kg −1 ·min −1 was significantly positively related with HDL-C and total cholesterol (TC) and negatively related with log systolic blood pressure (SBP). After adjusting for body mass index (BMI) in the analysis of covariance, the highest category of METs · hr/week ( 23) had significantly higher HDL-C than other lower categories. The highest category ofVO 2 max ( 33 ml·kg −1 ·min −1 ) had significantly higher HDL-C and TC and lower SBP than the lowest category. In conclusion, METs · hr/week was valid measures for quantifying physical activity, and the goals of METs · hr/week andVO 2 max in ml·kg −1 ·min −1 set in the Exercise Guide 2006 were valid.VO 2 max in ml·kg −1 ·min −1 was related to greater number of CHD risk factors than METs · hr/week in young women.